As with all medical conditions, there may be many causal factors. Further relevant information on causes of Achard syndrome may be found in:
16 MEDICAL BOOKS ONLINE! Review excerpts from medical books online, free, without registration, for more information about the causes of Achard syndrome.
Marfan syndrome is inherited as an autosomal dominant trait of chromosome 15. It's caused by mutations in gene fibrillin-1, producing changes in elastic tissues, especially of the aorta, eye, and skin. Mutations of fibrillin-1 also cause overgrowth of long bones. In 85% of patients with this disease, the family history confirms Marfan syndrome in one parent as well. In the remaining 15%, a negative family history suggests a fresh mutation, possibly from advanced paternal age.
Source: Professional Guide to Diseases (Eighth Edition), 2005
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