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Attempts to stop the degenerative process have met with little success. Therefore, treatment of Marfan syndrome is basically aimed at relieving symptoms — for example, surgical repair of aneurysms and ocular deformities. In young patients with early dilation of the aorta, prompt treatment with beta-adrenergic blockers may decrease ventricular ejection and protect the aorta; extreme dilation requires surgical replacement of the aorta and the aortic valve. Steroids and sex hormones have been successful (especially in girls) in inducing precocious puberty and early epiphyseal closure to prevent abnormal adult height. Genetic counseling is important, particularly because pregnancy and resultant increased cardiovascular workload can produce aortic rupture.
Source: Professional Guide to Diseases (Eighth Edition), 2005
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