The list of treatments mentioned in various sources for Acral lentiginous melanoma includes the following list. Always seek professional medical advice about any treatment or change in treatment plans.
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A patient with malignant melanoma requires surgical resection to remove the tumor. The extent of resection depends on the size and location of the primary lesion. Closure of a wide resection may require a skin graft. Surgical treatment may also include regional lymphadenectomy.
Deep primary lesions may merit adjuvant chemotherapy and biotherapy to eliminate or reduce the number of tumor cells. Clinical trials are currently under way to evaluate the effectiveness of isolated limb perfusion as chemotherapy for the management of malignant melanomas of extremities. Radiation therapy is usually reserved for metastatic disease. It doesn't prolong survival but may reduce tumor size and relieve pain.
Regardless of the treatment method, melanomas require close long-term follow-up to detect metastasis and recurrences. Statistics show that 13% of recurrences develop more than 5 years after primary surgery.
Source: Professional Guide to Diseases (Eighth Edition), 2005
A patient with malignant melanoma requires surgical resection to remove the tumor. The extent of resection depends on the size and location of the primary lesion. Closure of a wide resection may require a skin graft. Surgical treatment may also include regional lymphadenectomy. Cutaneous melanoma is nearly 100% curable by excision if diagnosed when malignant cells are confined to the epidermis.
Deep primary lesions may merit adjuvant chemotherapy and biotherapy or immunotherapy to eliminate or reduce the number of tumor cells. Radiation therapy is usually reserved for metastatic disease; gene therapy may also be a treatment option.
Regardless of the treatment method, melanomas require close, long-term follow-up to detect metastasis and recurrences.
UNDER STUDY: Nerve fiber loss may provide an explanation for the invisible neurologic deficits experienced by many patients with MS. The axons decide the presence or absence of function. Loss of myelin doesn’t correlate with loss of function.
The prognosis varies. MS may progress rapidly,. It can disable the patient by early adulthood, and it also holds the potential to cause death within months of onset. However, 70% of patients lead active, productive lives with prolonged remissions.
Terms to describe MS forms include:
❑ relapsing-remitting — clear relapses (or acute attacks or exacerbations) with full recovery or partial recovery and lasting disability. Between the attacks, there’s no worsening of the disease. This type accounts for up to 90% of all cases.
❑ primary progressive — steady progression or worsening of the disease from the onset with minor recovery or plateaus. This form is uncommon and may involve different brain and spinal cord damage than other forms.
❑ secondary progressive — begins as a pattern of clear-cut relapses and recovery but becomes steadily progressive and worsens between acute attacks.
❑ progressive relapsing — steadily progressive from the onset but also has clear acute attacks. This form is rare.
Source: Handbook of Diseases, 2003
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