Symptoms of Adrenal adenoma, familial
Symptoms of Adrenal adenoma, familial
The list of signs and symptoms mentioned in various sources
for Adrenal adenoma, familial includes the 65
symptoms listed below:
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Copyright notice for book excerpts: Copyright © 2008 Lippincott Williams & Wilkins. All rights reserved.
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Symptoms of Adrenal adenoma, familial: Online Medical Books
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Adrenal crisis:
Signs and Symptoms
(Professional Guide to Diseases (Eighth Edition))
Profound weakness, nausea, vomiting, hypotension, dehydration, high fever followed by hypothermia, vascular collapse, renal shutdown, coma
» READ BOOK EXCERPT ONLINE »
Source: Professional Guide to Diseases (Eighth Edition), 2005
Adrenal hypofunction:
Signs and symptoms
(Professional Guide to Diseases (Eighth Edition))
Adrenal hypofunction typically produces such effects as weakness, fatigue, weight loss, and various GI disturbances, such as nausea, vomiting, anorexia, and chronic diarrhea. When primary, the disorder usually causes a conspicuous bronze coloration of the skin. The patient appears to be deeply suntanned, especially in the creases of the hands and over the metacarpophalangeal joints, the elbows, and the knees. He may also exhibit a darkening of scars, areas of vitiligo (absence of pigmentation), and increased pigmentation of the mucous membranes, especially the buccal mucosa. Abnormal skin and mucous membrane coloration results from decreased secretion of cortisol (one of the glucocorticoids), which causes the pituitary gland to simultaneously secrete excessive amounts of corticotropin and melanocyte-stimulating hormone (MSH).
Associated cardiovascular abnormalities in adrenal hypofunction include orthostatic hypotension, decreased cardiac size and output, and a weak, irregular pulse. Other clinical effects include decreased tolerance for even minor stress, poor coordination, fasting hypoglycemia (due to decreased gluconeogenesis), and a craving for salty food. Adrenal hypofunction may also retard axillary and pubic hair growth in females, decrease the libido (from decreased androgen production) and, in severe cases, cause amenorrhea.
Secondary adrenal hypofunction produces similar clinical effects but without hyperpigmentation because corticotropin and MSH levels are low. Because aldosterone secretion may continue at fairly normal levels in secondary adrenal hypofunction, this condition doesn’t necessarily cause accompanying hypotension and electrolyte abnormalities.
Alert Adrenal crisis produces profound weakness, fatigue, nausea, vomiting, hypotension, dehydration and, occasionally, high fever followed by hypothermia. If untreated, this condition can ultimately lead to vascular collapse, renal shutdown, coma, and death.
» READ BOOK EXCERPT ONLINE »
Source: Professional Guide to Diseases (Eighth Edition), 2005
Hyperaldosteronism:
Signs and symptoms
(Professional Guide to Diseases (Eighth Edition))
Most clinical effects of hyperaldosteronism result from hypokalemia, which increases neuromuscular irritability and produces muscle weakness; intermittent, flaccid paralysis; fatigue; headaches; paresthesia; and, possibly, tetany (resulting from metabolic alkalosis), which can lead to hypocalcemia.
Diabetes mellitus is common, perhaps because hypokalemia interferes with normal insulin secretion. Hypertension and its accompanying complications are also common. Other characteristic findings include visual disturbances and loss of renal concentrating ability, resulting in nocturnal polyuria and polydipsia. Azotemia indicates chronic potassium depletion nephropathy.
» READ BOOK EXCERPT ONLINE »
Source: Professional Guide to Diseases (Eighth Edition), 2005
Adrenal hypofunction:
Signs and symptoms
(Handbook of Diseases)
Signs and symptoms vary with the type of adrenal hypofunction.
Primary hypofunction
Addison’s disease typically produces weakness, fatigue, weight loss, nausea, vomiting, and anorexia. Asthenia (constant fatigue) is the cardinal symptom, most evident in times of stress.
The disorder also usually causes a conspicuous bronze coloration of the skin. The patient appears to be deeply suntanned, especially in the creases of the hands and over the metacarpophalangeal joints, the elbows, and the knees. He also may exhibit a darkening of scars, areas of vitiligo (absence of pigmentation), and increased pigmentation of the mucous membranes, especially the buccal mucosa. Such abnormal skin and mucous membrane coloration results from decreased secretion of cortisol (a glucocorticoid), which causes the pituitary gland to simultaneously secrete excessive amounts of corticotropin and melanocyte-stimulating hormone (MSH).
Associated cardiovascular abnormalities include orthostatic hypotension, decreased cardiac size and output, and a weak, irregular pulse.
Other signs and symptoms include decreased tolerance for even minor stress, fasting hypoglycemia (due to decreased gluconeogenesis), and a craving for salty food due to decreased mineralocorticoid secretion, which normally causes salt retention.
GENDER INFLUENCE: In women with adrenal hypofunction, androgen levels are low, though they may be treated with daily replacement of 25 to 50 mg of dehydroepiandrosterone to improve quality of life and skeletal density. Also, axillary and pubic hair may be decreased due to loss of adrenal androgens.
Secondary hypofunction
Secondary hypofunction produces signs and symptoms similar to those of primary hypofunction but without hyperpigmentation because corticotropin and MSH levels are low. Because aldosterone secretion may continue at fairly normal levels in those with secondary adrenal hypofunction, this condition doesn’t necessarily cause accompanying hypotension and electrolyte abnormalities.
Adrenal crisis
Besides producing profound weakness, adrenal crisis also causes fatigue, nausea, vomiting, hypotension, dehydration and, occasionally, high fever followed by hypothermia. If untreated, this condition can ultimately lead to vascular collapse, renal shutdown, coma, and death.
» READ BOOK EXCERPT ONLINE »
Source: Handbook of Diseases, 2003
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About signs and symptoms of Adrenal adenoma, familial:
The symptom information on this page
attempts to provide a list of some possible signs and symptoms of Adrenal adenoma, familial.
This signs and symptoms information for Adrenal adenoma, familial has been gathered from various sources,
may not be fully accurate,
and may not be the full list of Adrenal adenoma, familial signs or Adrenal adenoma, familial symptoms.
Furthermore, signs and symptoms of Adrenal adenoma, familial may vary on an individual basis for each patient.
Only your doctor can provide adequate diagnosis of any signs or symptoms and whether they
are indeed Adrenal adenoma, familial symptoms.
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