Adrenoleukodystrophy

Adrenoleukodystrophy: Introduction

Adrenoleukodystrophy: Adrenoleukodystrophy (ALD) is a rare, inherited metabolic disorder that afflicts the young boy Lorenzo Odone, whose story is told in the 1993 film "Lorenzo's ... more about Adrenoleukodystrophy.

Adrenoleukodystrophy: A rare disorder which has characteristic symptoms of Addison disease (adrenocortical insufficiency) and Schilder disease (cerebral sclerosis). Bronze skin, brain sclerosis and demyelination are the main symptoms. More detailed information about the symptoms, causes, and treatments of Adrenoleukodystrophy is available below.

Symptoms of Adrenoleukodystrophy

• Seizures
• Impaired motor function
• Impaired vision
• Swallowing difficulties
• Attention problems
• more symptoms...»

See full list of 46 symptoms of Adrenoleukodystrophy

Home Diagnostic Testing

Home medical testing related to Adrenoleukodystrophy:

• Fatigue: Related Home Tests:
  • Home Anemia Tests
  • Home Thyroid Gland Function Tests
  • Home Adrenal Gland Function Tests
  • Home Calcium Deficiency Tests
  • Sleep Apnea Testing
  • Home HIV Tests
• Adrenal Gland Health: Home Testing:
  • Home Adrenal Function Testing
  • Home Thyroid Function Tests
• Nerve Neuropathy: Related Home Testing:
  • Home Diabetes Test Kits
  • Home Blood Glucose Testing Kits
• Brain & Neurological Disorders: Related Home Testing:
  • ADHD -- Home Tests
  • Drug Screening Kits
• more tests...»

Adrenoleukodystrophy: Complications

Review possible medical complications related to Adrenoleukodystrophy:

• Death from 6 months to 4 years from onset of neurological signs
• more complications...»

Medical Textbooks Online about Adrenoleukodystrophy

Book excerpts: Copyright © 2008 Lippincott Williams & Wilkins. All rights reserved.

Wrongly Diagnosed with Adrenoleukodystrophy?

• Misdiagnosis of Adrenoleukodystrophy
• Failure to diagnose Adrenoleukodystrophy
• Hidden causes of Adrenoleukodystrophy (possibly wrongly diagnosed)
• Undiagnosed: Adrenoleukodystrophy

Adrenoleukodystrophy: Self Assessment Tools

• Stroke -- Self Assessment Tools
• more tools...»

Adrenoleukodystrophy: Marketplace Products, Discounts & Offers

Products, offers and promotion categories available for Adrenoleukodystrophy:

• Stroke
• Brain
• more product offers...»

Adrenoleukodystrophy: Undiagnosed Conditions

Commonly undiagnosed diseases in related medical categories:

• Brain & Neurological Disorders: Undiagnosed:
  • Adult ADHD -- Undiagnosed - ADHD can be undiagnosed in adults.
  • ADHD -- Undiagnosed
  • Alzheimer Disease -- Undiagnosed
  • Migraine -- Undiagnosed
  • Concentration Disorders -- Undiagnosed
  • Stroke -- Undiagnosed
  • Bipolar Disorder -- Undiagnosed
  • Schizophrenia -- Undiagnosed
  • Epilepsy -- Undiagnosed
• more undiagnosed conditions...»

Misdiagnosis and Adrenoleukodystrophy

Undiagnosed stroke leads to misdiagnosed aphasia: BBC News UK reported on a man who had been institutionalized and treated for mental illness because he suffered from sudden inability to speak. This was initially...read more »

Dementia may be a drug interaction: A common scenario in aged care is for a patient to show mental decline to dementia. Whereas this can, of course, occur due to various...read more »

Mild traumatic brain injury often remains undiagnosed: Although the symptoms of severe brain injury are hard to miss, it is less clear for milder injuries, or even those causing a...read more »

MTBI misdiagnosed as balance problem: When a person has symptoms such as vertigo or dizziness, a diagnosis of brain injury may go overlooked. This is particularly true of mild traumatic brain injury (MTBI), for which...read more »

Brain pressure condition often misdiagnosed as dementia: A condition that results from an excessive pressure of CSF within the brain is often misdiagnosed. It may be misdiagnosed as Parkinson's...read more »

Post-concussive brain injury often misdiagnosed: A study found that soldiers who had suffered a concussive injury in battle often were misdiagnosed on their...read more »

Children with migraine often misdiagnosed: A migraine often fails to be correctly diagnosed in pediatric patients. These patients are not the typical migraine sufferers, but...read more »

Vitamin B12 deficiency under-diagnosed: The condition of Vitamin B12 deficiency is a possible misdiagnosis of various conditions, such as multiple sclerosis...read more »

Read more about Misdiagnosis and Adrenoleukodystrophy

Adrenoleukodystrophy: Research Doctors & Specialists

Research related physicians and medical specialists:

• Nerve Specialists:
  • Neuromusculoskeletal Medicine
  • Neurology (Brain/CNS Specialists)
  • Pediatric Neurology (Child Brain Specialist)
  • Spinal Cord Injury Medicine
• Neurology (Brain/CNS Specialists):
  • Pediatric Neurosurgery (Child Neurosurgeon)
  • Clinical Neurophysiology
  • Neurodevelopment Disabilities
  • Neurosurgery (Brain Surgery)
  • Neuromusculoskeletal Medicine (Nerve/Muscle/Bone Specialists)
  • Neuroradiology
  • Vascular Neurology
  • Neuropathology
  • Otology / Neurotology (Ear/Hearing Specialists)
• Stroke & Vascular Specialists:
  • Vascular Neurology (Brain Blood Vessels)
  • Vascular & Interventional Radiology
  • Vascular Surgery (Blood Vessel Surgeon)
  • Neuropathology (Brain Diagnostics)
• more specialists...»

Other doctor, physician and specialist research services:

• Rate Your Doctor Online
• Research Your Doctor Online
• Review Patient Surveys About Your Doctor
• Research local specialists including ratings, affiliations, and sanctions.

Adrenoleukodystrophy: Rare Types

Rare types of diseases and disorders in related medical categories:

• Brain & Neurological Disorders: Rare Types:
  • Adult ADHD -- Rare Types
  • ADHD -- Rare Types
  • Alzheimer Disease -- Rare Types
  • Migraine -- Rare Types
  • Concentration Disorders -- Rare Types
  • Stroke -- Rare Types
  • Bipolar Disorder -- Rare Types
  • Schizophrenia -- Rare Types
  • Epilepsy -- Rare Types
• more rare diseases...»

Causes of Adrenoleukodystrophy

Read more about causes of Adrenoleukodystrophy.

More information about causes of Adrenoleukodystrophy:

• Adrenoleukodystrophy as a symptom

News Archives for Adrenoleukodystrophy

Medical news articles related to Adrenoleukodystrophy include:

• Health Tip: X-Rays at the Dentist
• Gene That Creates Cerebral Cortex Discovered
• more health news...»

Source: HealthDay News

Videos for Adrenoleukodystrophy

Patient Surveys for Adrenoleukodystrophy

• Patient Profile Survey
  Take Survey  View Results

Prognosis for Adrenoleukodystrophy

Prognosis for Adrenoleukodystrophy: Prognosis for patients with ALD is generally poor except after successful bone marrow transplantation. Death may occur within 1 to 10 years after the onset of symptoms due to disease progression. (Source: excerpt from NINDS Adrenoleukodystrophy Information Page: NINDS)

More about prognosis of Adrenoleukodystrophy

Reseach about Adrenoleukodystrophy

Visit our research pages for current research about Adrenoleukodystrophy treatments.

Clinical Trials for Adrenoleukodystrophy

The US based website ClinicalTrials.gov lists information on both federally and privately supported clinical trials using human volunteers.

Some of the clinical trials listed on ClinicalTrials.gov for Adrenoleukodystrophy include:

• Study of Glyceryl Trierucate and Glyceryl Trioleate (Lorenzo's Oil) Therapy in Male Children With Adrenoleukodystrophy - This study is currently recruiting patients (Current: 23 Nov 2006) - glyceryl trierucate,glyceryl trioleate
• Study of Bile Acids in Patients With Peroxisomal Disorders - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - chenodeoxycholic acid,cholic acid,ursodiol
• Randomized Study of Beta Interferon and Thalidomide in Patients With Adrenoleukodystrophy - This study has been completed (Current: 23 Nov 2006) - glyceryl trierucate,glyceryl trioleate,interferon beta,thalidomide
• Study of Pulmonary Complications in Pediatric Patients With Storage Disorders Undergoing Allogeneic Hematopoietic Stem Cell Transplantation - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Study of Oral Cholic Acid in Patients With Inborn Errors of Bile Acid Synthesis - This study has been completed (Current: 23 Nov 2006)
• more trials...»

See full list of 9 Clinical Trials for Adrenoleukodystrophy

Statistics for Adrenoleukodystrophy

• Medical statistics for Adrenoleukodystrophy
• Prevalence and incidence statistics for Adrenoleukodystrophy
• Death and Mortality statistics for Adrenoleukodystrophy
• Society statistics for Adrenoleukodystrophy

Adrenoleukodystrophy: Broader Related Topics

• Leukodystrophy
• Leukodystrophy
• Brain conditions
• Genetic Disease
• Spinal Cord Disorders
• more types...»

Types of Adrenoleukodystrophy

Types of Adrenoleukodystrophy

• Classic childhood ALD - severe form in boys
• Adult-onset ALD - milder form in young adults
• Female carrier ALD - mild form in female carrying the gene.
• Neonatal ALD
• more types...»

Read more about Types of Adrenoleukodystrophy

Stories from Users Related to Adrenoleukodystrophy

• Adrenal dysfunction?
• skin/adrenal problems PLEASE READ
• My child has cerebral atrophy with Ataxia
• Addisons Disease vs Fibromyalgia
• cerebral atrophy
• So many untreated symptoms... enlarged liver, cerebral atrophy, acid reflux, etc.
• bronze skin.
• New with Addison's disease, Help
• addisons disease
• please help my mum! Paraplegia
• Is it Addison's Disease?
• x-ray help
• Leukodystrophy
• X-linked agamglobulinemia
• Arm atrophy
• Parkinson's or Adrenal Carncinoma??
• Addison's Disease
• Severe adrenal rushes
• paraplegia....
• atrophying skin?

Related forums and medical stories:

• Brain Conditions (246)
  • arachnoid cyst
  • Pain/Pressure in back of head when I laugh
  • Fluid running down back of my head feeling
  • "ice Pick" Headaches
  • vertigo + other symptoms
  • More user stories

User Interactive Forums

Read about other experiences, ask a question about Adrenoleukodystrophy, or answer someone else's question, on our message boards:

• I can not get a diagnosis. Please help.
• Tell us your medical story.
• Share your misdiagnosis story.
• What is the best treatment for this?
• See all the forums.

Article Excerpts about Adrenoleukodystrophy

Genes and Disease by the National Center for Biotechnology (Excerpt)

Adrenoleukodystrophy (ALD) is a rare, inherited metabolic disorder that afflicts the young boy Lorenzo Odone, whose story is told in the 1993 film "Lorenzo's oil." In this disease, the fatty covering (myelin sheath) on nerve fibers in the brain is lost, and the adrenal gland degenerates, leading to progressive neurological disability and death. (Source: Genes and Disease by the National Center for Biotechnology)

NINDS Adrenoleukodystrophy Information Page: NINDS (Excerpt)

Adrenoleukodystrophy (ALD) is a rare, genetic disorder characterized by the breakdown or loss of the myelin sheath surrounding nerve cells in the brain and progressive dysfunction of the adrenal gland. ALD is one of a group of genetic disorders called the leukodystrophies that cause damage to the myelin sheath, the fatty covering — which acts as an insulator — on nerve fibers in the brain. (Source: excerpt from NINDS Adrenoleukodystrophy Information Page: NINDS)

Definitions of Adrenoleukodystrophy:

A syndrome combining the characteristics of adrenocortical insufficiency (Addison disease) with those of cerebral sclerosis (Schilder disease). Skin bronzing and sclerosis of the brain and demyelination are the principal manifestations. - (Source - Diseases Database)

Adrenoleukodystrophy is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH). This means that Adrenoleukodystrophy, or a subtype of Adrenoleukodystrophy, affects less than 200,000 people in the US population.
Source - National Institutes of Health (NIH)