When combined, certain drugs, medications, substances or toxins may react causing Adverse reaction as a symptom.
The list below is incomplete and various other drugs or substances may cause your symptoms. Always advise your doctor of any medications or treatments you are using, including prescription, over-the-counter, supplements, herbal or alternative treatments.
See full list of 180 drug interactions causing Adverse reaction
As with all medical conditions, there may be many causal factors. Further relevant information on causes of Adverse reaction may be found in:
16 MEDICAL BOOKS ONLINE! Review excerpts from medical books online, free, without registration, for more information about the causes of Adverse reaction.
Hemolytic reactions follow transfusion of mismatched blood. Transfusion of serologically incompatible blood triggers the most serious reaction, marked by intravascular agglutination of red blood cells (RBCs). The recipient’s antibodies (immunoglobulin [Ig] G or IgM) attach to the donated RBCs, leading to widespread clumping and destruction of the recipient’s RBCs and, possibly, the development of disseminated intravascular coagulation (DIC) and other serious effects.
Transfusion of Rh-incompatible blood triggers a less serious reaction within several days to 2 weeks. Rh reactions are most common in females sensitized to RBC antigens by prior pregnancy or by unknown factors (such as bacterial or viral infection) and in people who have received more than five transfusions. (See Understanding the Rh system.)
Allergic reactions are fairly common but only occasionally serious. In this type of reaction, transfused soluble antigens react with surface IgE molecules on mast cells and basophils, causing degranulation and release of allergic mediators. Antibodies against IgA in an IgA-deficient recipient can also trigger a severe allergic reaction (anaphylaxis).
Febrile nonhemolytic reactions, the most common type of reaction, apparently develop when cytotoxic or agglutinating antibodies in the recipient’s plasma attack antigens on transfused lymphocytes, granulocytes, or plasma cells.
Although fairly uncommon, bacterial contamination of donor blood can occur during donor phlebotomy. Offending organisms are usually gram-negative, especially Pseudomonas species, Citrobacter freundii, and Escherichia coli.
Contamination of donor blood with viruses, such as hepatitis, cytomegalovirus, and malaria, is also possible.
Source: Professional Guide to Diseases (Eighth Edition), 2005
Certain chemicals can cause a photosensitivity reaction, including dyes, coal tar, and furocoumarin compounds found in plants. The list of drugs that can cause photosensitivity reactions is extensive and includes many drugs within each of the following general categories: antibiotics (especially tetracycline), antidepressants, antihistamines, anticancer agents, antiparasitic agents, antipsychotic agents, diuretics, hypoglycemics, nonsteroidal anti-inflammatories, sunscreens, and miscellaneous agents, such as cardiac glycosides, hormonal contraceptives, and acne medications.
Berlock dermatitis, a specific photosensitivity reaction, results from the use of oil of bergamot — a common component of perfumes, colognes, and pomades.
Source: Professional Guide to Diseases (Eighth Edition), 2005
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