Diagnosis of Adverse reaction

Adverse reaction Diagnosis: Book Excerpts

• Diagnosis - Blood transfusion reaction
• Diagnosis - Photosensitivity reactions

Diagnostic Tests for Adverse reaction: Online Medical Books

16 MEDICAL BOOKS ONLINE! Review excerpts from medical books online, free, without registration, for more information about diagnostis of Adverse reaction.

Blood transfusion reaction: Diagnosis
(Professional Guide to Diseases (Eighth Edition))

CONFIRMING DIAGNOSIS Confirming a hemolytic transfusion reaction requires proof of blood incompatibility and evidence of hemolysis, such as hemoglobinuria, anti-A or anti-B antibodies in the serum, low serum Hb levels, and elevated bilirubin levels.

If you suspect such a reaction, have the patient’s blood retyped and crossmatched with the donor’s blood. After a hemolytic transfusion reaction, laboratory tests will show increased indirect bilirubin levels, decreased haptoglobin levels, increased serum Hb levels, and Hb in the urine. As the reaction progresses, tests may show signs of DIC (thrombocytopenia, increased prothrombin time, and decreased fibrinogen level) and acute tubular necrosis (increased blood urea nitrogen and serum creatinine levels).

A blood culture to isolate the causative organism should be done when bacterial contamination is suspected.

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Source: Professional Guide to Diseases (Eighth Edition), 2005

Photosensitivity reactions: Diagnosis
(Professional Guide to Diseases (Eighth Edition))

Characteristic skin eruptions in sun-exposed areas and a patient history of recent exposure to light or certain chemicals suggest a photosensitivity reaction. A photopatch test for ultraviolet A and B (UVA and UVB) done while the patient is on the drug may aid diagnosis and identify the causative light wavelength. Other studies must rule out connective tissue disease, such as lupus erythematosus and porphyrias.

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Source: Professional Guide to Diseases (Eighth Edition), 2005

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