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Diseases » AIDS » Research
 

Cure Research for AIDS

Medications currently used in research into the treatment of AIDS:

Note:You must always seek professional medical advice about any treatment or change in treatment plans.

Some of the different medications being used in the research into treatment of AIDS include:

Curable Types of AIDS

Possibly curable or rare types of AIDS include:

  • Pneumocystitis carinii pneumonia related AIDS
  • Tuberculosis related AIDS
  • Toxoplasmosis related AIDS
  • Herpes zoster related AIDS
  • more curable types...»

Rare Types of AIDS:

Some rare types of AIDS include:

  • Pneumocystitis carinii pneumonia related AIDS
  • Tuberculosis related AIDS
  • Toxoplasmosis related AIDS
  • more rare types...»

Medical Research Breakthroughs and AIDS

OPAL therapy for HIV infection: Australian researchers have unveiled a new immunotherapy technique to help prevent the progression from HIV infection to AIDS. There is an overwhelming need for effective immunotherapies for HIV, as current therapies are expensive, impractical, and often highly toxic. The new study proposes a technique named OPAL therapy--Overlapping Peptide-pulsed Autologous CeLls--a reinfusion of fresh blood cells incubating with overlapping SIV peptides. The OPAL technique was successfully tested in animal trials for stimulation of immunity, control of virus levels, and prevention of AIDS. Vaccination diminished the levels of virus 10 fold lower than in controls and was shown to be durable for over one year past initial vaccination. Therefore, viral replication was shown to be prolonged and more manageable resulting in fewer deaths from AIDS. The researchers plan to conduct future OPAL- therapy clinical trials in HIV infected humans.

Cure Research discussion for AIDS:

Clinical Trials for AIDS Therapies, NIAID Fact Sheet: NIAID (Excerpt)

NIAID-supported clinical trials have:

  • demonstrated and defined the efficacy of zidovudine (AZT), zalcitibine (ddC), didanosine (ddI) and stavudine (d4T) as monotherapies and in combination regimens for a wide variety of clinical conditions.
  • demonstrated that combination regimens employing two or more antiretroviral agents are more effective than AZT monotherapy, particularly early in disease.
  • defined the standard of care for acute treatment and prophylaxis of Pneumocystis carinii pneumonia, treatment and maintenance for cryptococcal meningitis (fluconazole), treatment and maintenance therapy for disseminated histoplasmosis (itraconazole), treatment of disseminated Mycobacterium avium complex (clarithromycin), management of cytomegalovirus retinitis and acyclovir-resistant herpes simplex (foscarnet).
  • assessed and validated assays for use as surrogate markers of drug effectiveness including p24 antigen, quantitative peripheral blood mononuclear cells (PBMC), microculture and DNA/RNA (PCR).
  • developed state-of-the-art study design methodology for HIV disease (e.g., endpoints) to permit rapid clinical and laboratory evaluation of antiretroviral compounds.
(Source: excerpt from Clinical Trials for AIDS Therapies, NIAID Fact Sheet: NIAID)

Clinical Trials for AIDS Therapies, NIAID Fact Sheet: NIAID (Excerpt)

NIAID's pediatric clinical research effort has significantly advanced the treatment and prevention of HIV infection in infants and children. Through clinical trials, NIAID has:

  • demonstrated that AZT therapy reduced dramatically the likelihood of childhood HIV infection resulting from transmission from infected mothers during pregnancy or delivery.
  • demonstrated that ddI or ddI plus AZT are superior to AZT monotherapy for children with symptomatic HIV infection or AIDS.
  • demonstrated the effectiveness of IVIG for preventing serious bacterial infections in children with HIV.
  • developed guidelines for the prevention of PCP in HIV-infected children.

Over the next several years, NIAID research will continue to define the standard of care for HIV-infected people of all ages. Particular emphasis will be placed on the use of combination regimens with protease inhibitors. (Source: excerpt from Clinical Trials for AIDS Therapies, NIAID Fact Sheet: NIAID)

Medical research for AIDS: medical news summaries:

The following medical news items are relevant to medical research for AIDS:


 » Next page: Deaths from AIDS

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