Clinical Trials for Alopecia Areata

Clinical trials are research studies conducted in an effort to improve overall patient health and care. Each trial involves running supervised tests to determine the effectiveness and safety of new drugs, procedures and/or devices with the aim of answering scientific questions about a disease or condition. Risks and side-effects are also evaluated during these trials with results ranging from being unpleasant, with side effects such as headaches, to more serious or even life-threatening risks. A clinical trial may be separated into phases, or steps, with each step designed to answer a separate research question. This maybe reflected in the trial name.

A brief description of each phase:

• Phase I: Usually designed to evaluate safety, determine a safe dosage range, and identify side effects on a small group of patients.
• Phase II: If Phase I is successful, the trial is then repeated with a larger group to further evaluate its effect and safety.
• Phase III: Trials are conducted on an ever larger group and are compared with the best current treatment while gathering more information on effect and safety.
• Phase IV: These studies monitor long-term side effects after the treatment has been marketed.

Clinical Trials data for Alopecia Areata is grouped into the following categories:-

• View by trial name
• View by drugs used in Alopecia Areata clinical trials

Clinical Trials by trial name

The format for each of the following is:

• The name of the trial,
• followed by whether the trial is recruiting patients,
  - The trial may not have started and not yet recruiting, or the trial may have started and do not need any more recruitements, or the trial may be completed.
  - Note**: Please follow the link to determine the current trial status.
• followed by a list of drug/s, if any, used in the trial

ClinicalTrials.gov has listed the following trials for Alopecia Areata:

• Alopecia Areata Registry - This study is currently recruiting patients (Current: 23 Nov 2006)
• Alefacept in Patients With Severe Scalp Alopecia Areata - This study is currently recruiting patients (Current: 23 Nov 2006) - Alefacept
• Efficacy Study of Latanoprost and Bimatoprost Solutions in Promoting Eyelash Growth in Patients With Alopecia Areata - This study is no longer recruiting patients (Current: 23 Nov 2006) - Latanoprost (Xalatan),Bimatoprost (Lumigan)
• Plaquenil for Alopecia Areata, Alopecia Totalis - This study is currently recruiting patients (Current: 23 Nov 2006) - Hydroxychloroquine
• Phase II Randomized Bilateral Comparison of Topical Targretin Gel 1% in Alopecia Areata - This study is currently recruiting patients (Current: 23 Nov 2006) - Targretin Gel 1%
• Characteristics of T Cells From Alopecia Areata Scalp Skin Before and After Treatment With Aldara 5% - This study has been completed (Current: 23 Nov 2006) - Aldara Cream 5%
• Response of Topical Capsaicin in Alopecia Areata - This study has been completed (Current: 23 Nov 2006) - Capsaicin
• Aldara for the Treatment of Extensive Alopecia Areata - This study has been completed (Current: 23 Nov 2006) - Aldara Cream 5%
• Alopecia Areata Registry and Immunogenetic Mechanisms - This study is currently recruiting patients (Current: 23 Nov 2006)

Drugs used in Clinical Trials for Alopecia Areata

The format for each of the following is:

• The drug,
• followed by the name of the trial,
• followed by whether the trial is recruiting patients,
  - The trial may not have started and not yet recruiting, or the trial may have started and do not need any more recruitements, or the trial may be completed.
  - Note**: Please follow the link to determine the current trial status.

ClinicalTrials.gov has listed the following drugs in trials for Alopecia Areata:

• Aldara Cream 5% - Aldara for the Treatment of Extensive Alopecia Areata - This study has been completed (Current: 23 Nov 2006)
• Aldara Cream 5% - Characteristics of T Cells From Alopecia Areata Scalp Skin Before and After Treatment With Aldara 5% - This study has been completed (Current: 23 Nov 2006)
• Alefacept - Alefacept in Patients With Severe Scalp Alopecia Areata - This study is currently recruiting patients (Current: 23 Nov 2006)
• Bimatoprost (Lumigan) - Efficacy Study of Latanoprost and Bimatoprost Solutions in Promoting Eyelash Growth in Patients With Alopecia Areata - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Capsaicin - Response of Topical Capsaicin in Alopecia Areata - This study has been completed (Current: 23 Nov 2006)
• Hydroxychloroquine - Plaquenil for Alopecia Areata, Alopecia Totalis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Latanoprost (Xalatan) - Efficacy Study of Latanoprost and Bimatoprost Solutions in Promoting Eyelash Growth in Patients With Alopecia Areata - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Targretin Gel 1% - Phase II Randomized Bilateral Comparison of Topical Targretin Gel 1% in Alopecia Areata - This study is currently recruiting patients (Current: 23 Nov 2006)

The trial data on this page has been sourced from

• The U.S. National Library of Medicine (NLM) together with ClinicalTrials.gov

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