As with all medical conditions, there may be many causal factors. Further relevant information on causes of Alpha 1-Antitrypsin Deficiency may be found in:
16 MEDICAL BOOKS ONLINE! Review excerpts from medical books online, free, without registration, for more information about the causes of Alpha 1-Antitrypsin Deficiency.
Mutations in the SERPINA1 gene result in lung disease through unopposed protease activity and in liver disease by intracellular retention of mutant α
Source: The 5-Minute Pediatric Consult, 2008
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