One common sign of amyloidosis is the presence of abnormally high amounts of protein in the urine, a condition known as proteinuria. Healthy kidneys prevent protein from entering the urine, so the presence of protein may be a sign that the kidneys aren't working properly. A physician who finds large amounts of protein in the urine may also perform a biopsy--take a small sample of tissue for examination under a microscope--to confirm amyloidosis. (Source: excerpt from Amyloidosis and Kidney Disease: NIDDK)
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In cardiac amyloidosis, other findings include faint heart sounds and an electrocardiogram showing low voltage and conduction or rhythm abnormalities resembling those characteristic of myocardial infarction. In hepatic amyloidosis, liver function studies are generally normal, except for a slightly elevated serum alkaline phosphatase level.
Source: Professional Guide to Diseases (Eighth Edition), 2005
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