Treatments for Amyloidosis
Amyloidosis: Is the Diagnosis Correct?
The first step in getting correct treatment is
to get a correct diagnosis.
Differential diagnosis list for Amyloidosis may include:
Hidden causes of Amyloidosis may be incorrectly diagnosed:
Amyloidosis: Research Doctors & Specialists
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Treatment statistics for Amyloidosis:
The following are statistics from various sources
about the treatment of Amyloidosis:
- High-dose dexamethasone had a positive response in less than 15% of amyloid patients with no cardiac involvement in the US (Amyloidosis: Recognition, Prognosis and Conventional Therapy, American Society of Hematology)
- 4.6 years was the median survival rate for AL amyloidosis patients who were treated with melphalan and autologous stem-cell transplantation (High-dose Melphalan and Autologous Stem-Cell transplantation in Patients with AL Amyloidosis, Annals of International Medicine, 2004;140:85-93)
- 13% mortality rate for AL amyloidosis patients 100 days after treatment with melphalan and stem-cell transplantation (High-dose Melphalan and Autologous Stem-Cell transplantation in Patients with AL Amyloidosis, Annals of International Medicine, 2004;140:85-93)
- 28% of AL amyloidosis patients showed a response to treatment with oral melphalan and prednisone in the US (Blood first Edition Paper, 2003;DOI 10.1182)
- 30% of AL amyloidosis patients who showed a response to treatment with oral melphalan and prednisone took a year to respond in the US (Blood first Edition Paper, 2003;DOI 10.1182)
Hospital statistics for Amyloidosis:
These medical statistics relate to hospitals, hospitalization and Amyloidosis:
- 0.008% (995) of hospital consultant episodes were for amyloidosis in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
- 86% of hospital consultant episodes for amyloidosis required hospital admission in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
- 57% of hospital consultant episodes for amyloidosis were for men in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
- 43% of hospital consultant episodes for amyloidosis were for women in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
- 23% of hospital consultant episodes for amyloidosis required emergency hospital admission in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
- more hospital information...»
Discussion of treatments for Amyloidosis:
No effective treatment has been found to reverse the effects of
amyloidosis. Combination drug therapy with melphalan (a cancer drug)
and prednisone (an anti-inflammatory steroid drug) may improve organ
function and survival rates by interrupting the growth of cells that
produce amyloid protein. These are the same drugs used in
chemotherapy to treat certain cancers, and they may have serious
side effects, such as nausea and vomiting, hair loss, and
fatigue. (Source: excerpt from
Amyloidosis and Kidney Disease: NIDDK)
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Book Excerpts: Treatment of Amyloidosis
Treatments of Amyloidosis: Online Medical Books
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Amyloidosis:
Treatment
(Professional Guide to Diseases (Eighth Edition))
Treatment is directed at eliminating the underlying cause and is mainly supportive. Transplantation may be useful for amyloidosis-induced renal failure, although the donor kidney may also develop amyloidosis. Patients with cardiac amyloidosis require conservative treatment to prevent dangerous arrhythmias. Malnutrition caused by malabsorption in end-stage GI involvement may require total parenteral nutrition.
» READ BOOK EXCERPT ONLINE »
Source: Professional Guide to Diseases (Eighth Edition), 2005
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