Clinical Trials for Amyotrophic lateral sclerosis

Clinical trials are research studies conducted in an effort to improve overall patient health and care. Each trial involves running supervised tests to determine the effectiveness and safety of new drugs, procedures and/or devices with the aim of answering scientific questions about a disease or condition. Risks and side-effects are also evaluated during these trials with results ranging from being unpleasant, with side effects such as headaches, to more serious or even life-threatening risks. A clinical trial may be separated into phases, or steps, with each step designed to answer a separate research question. This maybe reflected in the trial name.

A brief description of each phase:

• Phase I: Usually designed to evaluate safety, determine a safe dosage range, and identify side effects on a small group of patients.
• Phase II: If Phase I is successful, the trial is then repeated with a larger group to further evaluate its effect and safety.
• Phase III: Trials are conducted on an ever larger group and are compared with the best current treatment while gathering more information on effect and safety.
• Phase IV: These studies monitor long-term side effects after the treatment has been marketed.

Clinical Trials data for Amyotrophic lateral sclerosis is grouped into the following categories:-

• View by trial name
• View by drugs used in Amyotrophic lateral sclerosis clinical trials

Clinical Trials by trial name

The format for each of the following is:

• The name of the trial,
• followed by whether the trial is recruiting patients,
  - The trial may not have started and not yet recruiting, or the trial may have started and do not need any more recruitements, or the trial may be completed.
  - Note**: Please follow the link to determine the current trial status.
• followed by a list of drug/s, if any, used in the trial

ClinicalTrials.gov has listed the following trials for Amyotrophic lateral sclerosis:

• Clinical Trial of High Dose CoQ10 in ALS - This study is currently recruiting patients (Current: 23 Nov 2006) - coenzyme Q10
• Early Treatment of Amyotrophic Lateral Sclerosis (ALS) With Nutrition and Non-Invasive Positive Pressure Ventilation (NIPPV) - This study is currently recruiting patients (Current: 23 Nov 2006)
• Study of Myobloc in the Treatment of Sialorrhea (Drooling) in Patients With Amyotrophic Lateral Sclerosis (ALS) - This study is currently recruiting patients (Current: 23 Nov 2006) - Botulinum toxin type B (Myobloc)
• Determinants of Disease Severity in Amyotrophic Lateral Sclerosis - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Phase II Study of Leuprolide and Testosterone for Men With Kennedy's Disease or Other Motor Neuron Disease - This study has been completed (Current: 23 Nov 2006) - leuprolide,testosterone
• Is There a Higher Than Expected Occurrence of Amyotrophic Lateral Sclerosis (ALS) Among Deployed Veterans as Compared to Non-Deployed Gulf War Veterans? - This study has been completed (Current: 23 Nov 2006)
• Insulin-Like Growth Factor-1 (IGF-1) in Amyotrophic Lateral Sclerosis (ALS) Trial - This study is no longer recruiting patients (Current: 23 Nov 2006) - insulin-like growth factor-1 (IGF-I)
• Minocycline to Treat Amyotrophic Lateral Sclerosis - This study is no longer recruiting patients (Current: 23 Nov 2006) - minocycline
• R(+) Pramipexole in Early Amyotrophic Lateral Sclerosis - This study is currently recruiting patients (Current: 23 Nov 2006) - R(+) pramipexole dihydrochloride monohydrate
• Frontotemporal Dementia and Amyotrophic Lateral Sclerosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• The Effect of Intensive Controlled Exercise in the Early Stages of Amyotrophic Lateral Sclerosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Study of the Effects Strengthening Exercises in Individuals With ALS - This study has been completed (Current: 23 Nov 2006)
• Amyotrophic Lateral Sclerosis Web Based Patient Care Database: ALSConnection.Org - This study is currently recruiting patients (Current: 23 Nov 2006)
• Exposure to Neurotoxins as Risk Factors for Amyotrophic Lateral Sclerosis - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Clinical Trial Ceftriaxone in Subjects With ALS - This study is currently recruiting patients (Current: 23 Nov 2006) - ceftriaxone
• Memantine for Disability in Amyotrophic Lateral Sclerosis (MEDALS) - This study is currently recruiting patients (Current: 23 Nov 2006) - Memantine
• Combination Therapy Selection Trial in Amyotrophic Lateral Sclerosis - This study is currently recruiting patients (Current: 23 Nov 2006) - celecoxib,creatine,minocycline
• Clinical Trial of Vitamin E to Treat Muscular Cramps in Patients With ALS - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - Vitamin E
• G-CSF Treatment for Amyotrophic Lateral Sclerosis: A RCT Study Assessing Clinical Response - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - Granulocyte-Colony Stimulating Factor
• Familial Amyotrophic Lateral Sclerosis: A Preliminary Study to Identify Subjects Who Might Be Willing to Participate in a Trial - This study is currently recruiting patients (Current: 23 Nov 2006)
• Genetic Epidemiology of Familial Amyotrophic Lateral Sclerosis (ALS) - This study is currently recruiting patients (Current: 23 Nov 2006)
• A Long-Term Extension Study of TCH346 and Placebo Administered Once Daily in Patients With Amyotrophic Lateral Sclerosis(ALS) - This study has been completed (Current: 23 Nov 2006) - TCH346
• Levetiracetam for Cramps, Spasticity and Neuroprotection in Motor Neuron Disease - This study is currently recruiting patients (Current: 23 Nov 2006) - Levetiracetam
• Trial of Sodium Valproate in Amyotrophic Lateral Sclerosis - This study is currently recruiting patients (Current: 23 Nov 2006) - Sodium Valproate
• Study of Creatine Monohydrate in Patients With Amyotrophic Lateral Sclerosis - This study is no longer recruiting patients (Current: 23 Nov 2006) - Creatine Monohydrate
• Efficacy and Safety Study of MCI-186 for Treatment of Amyotrophic Lateral Sclerosis (ALS) - This study is currently recruiting patients (Current: 23 Nov 2006) - Edaravone (Radicut)
• Noninvasive Ventilation in ALS Patients With Mild Respiratory Involvement - This study is currently recruiting patients (Current: 23 Nov 2006)
• Study Evaluating TCH346 and Placebo Administered Once Daily in Patients With Amyotrophic Lateral Sclerosis (ALS) - This study is no longer recruiting patients (Current: 23 Nov 2006) - TCH346
• Clinical Trial of Creatine in Amyotrophic Lateral Sclerosis [ALS] - This study has been completed (Current: 23 Nov 2006) - Creatine
• Clinical Trial of Creatine in Amyotrophic Lateral Sclerosis - This study has been completed (Current: 23 Nov 2006) - Creatinine
• Exogenous Toxicants and Genetic Susceptibility in ALS - This study has been completed (Current: 23 Nov 2006)
• Safety/Efficacy of AVP-923 in the Treatment of Emotional Lability (Uncontrolled Crying & Laughing) in Patients With ALS - This study has been completed (Current: 23 Nov 2006) - AVP-923
• Nuclear Magnetic Spectroscopy Imaging to Evaluate Primary Lateral Sclerosis, Hereditary Spastic Paraplegia and Amyotrophic Lateral Sclerosis - This study has been completed (Current: 23 Nov 2006)
• A 12-Week, Multicenter, Safety and Dose-Ranging Study of 3 Oral Doses of TCH346 in Patients With Amyotrophic Lateral Sclerosis - This study has been completed (Current: 23 Nov 2006) - TCH346
• Creatine for the Treatment of Amyotrophic Lateral Sclerosis - This study has been completed (Current: 23 Nov 2006) - creatine monohydrate
• Safety Study of Oral Sodium Phenylbutyrate in Subjects With ALS (Amyotrophic Lateral Sclerosis) - This study is currently recruiting patients (Current: 23 Nov 2006) - sodium phenylbutyrate
• Phase II Study Using Thalidomide for the Treatment of ALS - This study is currently recruiting patients (Current: 23 Nov 2006) - Thalidomide
• Influence of G-CSF and EPO on Associative Learning and Motor Skills - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - granulocyte - colony stimulating factor (G-CSF),erythropoetin (EPO)
• Clinical Trial of Glatiramer Acetate in Amyotrophic Lateral Sclerosis (ALS) - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - Parenteral Drug / 40 mg Glatiramer Acetate
• Mitochondrial Functions and Oxidative Stress in ALS Patients - This study is currently recruiting patients (Current: 23 Nov 2006)
• Effects of Gastrostomy on Amyotrophic Lateral Sclerosis - This study has been completed (Current: 23 Nov 2006)
• Confirmation of Self-Reported Amyotrophic Lateral Sclerosis Cases in the AARP-Diet and Health Study - This study is currently recruiting patients (Current: 23 Nov 2006)
• Tamoxifen Therapy in Amyotrophic Lateral Sclerosis [ALS] - This study is no longer recruiting patients (Current: 23 Nov 2006) - Tamoxifen
• Pilot-Study of Thalidomide in Amyotrophic Lateral Sclerosis (ALS) - This study is currently recruiting patients (Current: 23 Nov 2006) - Thalidomide (drug)
• A Multicenter, Dose Ranging Safety and Pharmacokinetics Study of Arimoclomol in ALS - This study is no longer recruiting patients (Current: 23 Nov 2006) - arimoclomol
• Amyotrophic Lateral Sclerosis and Frontotemporal Dementia - This study is currently recruiting patients (Current: 23 Nov 2006)
• Amyotrophic Lateral Sclerosis (ALS) Veterans Registry - This study is currently recruiting patients (Current: 23 Nov 2006)
• Exposure to Neurotoxins as Risk Factors for ALS - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Collection of Blood Samples for DNA in Motor Neuron Disease - This study is currently recruiting patients (Current: 23 Nov 2006)
• Study of "Post-Polio Syndrome" - This study has been completed (Current: 23 Nov 2006)
• Brain Function in Primary Lateral Sclerosis and Amyotrophic Lateral Sclerosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Clinical Trial of High Dose CoQ10 in ALS - This study is currently recruiting patients (Current: 23 Nov 2006) - coenzyme Q10
• Early Treatment of Amyotrophic Lateral Sclerosis (ALS) With Nutrition and Non-Invasive Positive Pressure Ventilation (NIPPV) - This study is currently recruiting patients (Current: 23 Nov 2006)
• Study of Myobloc in the Treatment of Sialorrhea (Drooling) in Patients With Amyotrophic Lateral Sclerosis (ALS) - This study is currently recruiting patients (Current: 23 Nov 2006) - Botulinum toxin type B (Myobloc)
• Study Evaluating TCH346 and Placebo Administered Once Daily in Patients With Amyotrophic Lateral Sclerosis (ALS) - This study is no longer recruiting patients (Current: 23 Nov 2006) - TCH346
• Noninvasive Ventilation in ALS Patients With Mild Respiratory Involvement - This study is currently recruiting patients (Current: 23 Nov 2006)
• Determinants of Disease Severity in Amyotrophic Lateral Sclerosis - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Phase II Study of Leuprolide and Testosterone for Men With Kennedy's Disease or Other Motor Neuron Disease - This study has been completed (Current: 23 Nov 2006) - leuprolide,testosterone
• Is There a Higher Than Expected Occurrence of Amyotrophic Lateral Sclerosis (ALS) Among Deployed Veterans as Compared to Non-Deployed Gulf War Veterans? - This study has been completed (Current: 23 Nov 2006)
• Insulin-Like Growth Factor-1 (IGF-1) in Amyotrophic Lateral Sclerosis (ALS) Trial - This study is no longer recruiting patients (Current: 23 Nov 2006) - insulin-like growth factor-1 (IGF-I)
• Minocycline to Treat Amyotrophic Lateral Sclerosis - This study is no longer recruiting patients (Current: 23 Nov 2006) - minocycline
• R(+) Pramipexole in Early Amyotrophic Lateral Sclerosis - This study is currently recruiting patients (Current: 23 Nov 2006) - R(+) pramipexole dihydrochloride monohydrate
• Frontotemporal Dementia and Amyotrophic Lateral Sclerosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• The Effect of Intensive Controlled Exercise in the Early Stages of Amyotrophic Lateral Sclerosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Study of the Effects Strengthening Exercises in Individuals With ALS - This study has been completed (Current: 23 Nov 2006)
• Amyotrophic Lateral Sclerosis Web Based Patient Care Database: ALSConnection.Org - This study is currently recruiting patients (Current: 23 Nov 2006)
• Exposure to Neurotoxins as Risk Factors for Amyotrophic Lateral Sclerosis - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Clinical Trial Ceftriaxone in Subjects With ALS - This study is currently recruiting patients (Current: 23 Nov 2006) - ceftriaxone
• Memantine for Disability in Amyotrophic Lateral Sclerosis (MEDALS) - This study is currently recruiting patients (Current: 23 Nov 2006) - Memantine
• Combination Therapy Selection Trial in Amyotrophic Lateral Sclerosis - This study is currently recruiting patients (Current: 23 Nov 2006) - celecoxib,creatine,minocycline
• Clinical Trial of Vitamin E to Treat Muscular Cramps in Patients With ALS - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - Vitamin E
• G-CSF Treatment for Amyotrophic Lateral Sclerosis: A RCT Study Assessing Clinical Response - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - Granulocyte-Colony Stimulating Factor
• Familial Amyotrophic Lateral Sclerosis: A Preliminary Study to Identify Subjects Who Might Be Willing to Participate in a Trial - This study is currently recruiting patients (Current: 23 Nov 2006)
• Genetic Epidemiology of Familial Amyotrophic Lateral Sclerosis (ALS) - This study is currently recruiting patients (Current: 23 Nov 2006)
• A Long-Term Extension Study of TCH346 and Placebo Administered Once Daily in Patients With Amyotrophic Lateral Sclerosis(ALS) - This study has been completed (Current: 23 Nov 2006) - TCH346
• Levetiracetam for Cramps, Spasticity and Neuroprotection in Motor Neuron Disease - This study is currently recruiting patients (Current: 23 Nov 2006) - Levetiracetam
• Trial of Sodium Valproate in Amyotrophic Lateral Sclerosis - This study is currently recruiting patients (Current: 23 Nov 2006) - Sodium Valproate
• Study of Creatine Monohydrate in Patients With Amyotrophic Lateral Sclerosis - This study is no longer recruiting patients (Current: 23 Nov 2006) - Creatine Monohydrate
• Efficacy and Safety Study of MCI-186 for Treatment of Amyotrophic Lateral Sclerosis (ALS) - This study is currently recruiting patients (Current: 23 Nov 2006) - Edaravone (Radicut)
• Clinical Trial of Creatine in Amyotrophic Lateral Sclerosis [ALS] - This study has been completed (Current: 23 Nov 2006) - Creatine
• Clinical Trial of Creatine in Amyotrophic Lateral Sclerosis - This study has been completed (Current: 23 Nov 2006) - Creatinine
• Exogenous Toxicants and Genetic Susceptibility in ALS - This study has been completed (Current: 23 Nov 2006)
• Safety/Efficacy of AVP-923 in the Treatment of Emotional Lability (Uncontrolled Crying & Laughing) in Patients With ALS - This study has been completed (Current: 23 Nov 2006) - AVP-923
• Nuclear Magnetic Spectroscopy Imaging to Evaluate Primary Lateral Sclerosis, Hereditary Spastic Paraplegia and Amyotrophic Lateral Sclerosis - This study has been completed (Current: 23 Nov 2006)
• A 12-Week, Multicenter, Safety and Dose-Ranging Study of 3 Oral Doses of TCH346 in Patients With Amyotrophic Lateral Sclerosis - This study has been completed (Current: 23 Nov 2006) - TCH346
• Creatine for the Treatment of Amyotrophic Lateral Sclerosis - This study has been completed (Current: 23 Nov 2006) - creatine monohydrate
• Safety Study of Oral Sodium Phenylbutyrate in Subjects With ALS (Amyotrophic Lateral Sclerosis) - This study is currently recruiting patients (Current: 23 Nov 2006) - sodium phenylbutyrate
• Phase II Study Using Thalidomide for the Treatment of ALS - This study is currently recruiting patients (Current: 23 Nov 2006) - Thalidomide
• Influence of G-CSF and EPO on Associative Learning and Motor Skills - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - granulocyte - colony stimulating factor (G-CSF),erythropoetin (EPO)
• Clinical Trial of Glatiramer Acetate in Amyotrophic Lateral Sclerosis (ALS) - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - Parenteral Drug / 40 mg Glatiramer Acetate
• Mitochondrial Functions and Oxidative Stress in ALS Patients - This study is currently recruiting patients (Current: 23 Nov 2006)
• Effects of Gastrostomy on Amyotrophic Lateral Sclerosis - This study has been completed (Current: 23 Nov 2006)
• Confirmation of Self-Reported Amyotrophic Lateral Sclerosis Cases in the AARP-Diet and Health Study - This study is currently recruiting patients (Current: 23 Nov 2006)
• Tamoxifen Therapy in Amyotrophic Lateral Sclerosis [ALS] - This study is no longer recruiting patients (Current: 23 Nov 2006) - Tamoxifen
• Pilot-Study of Thalidomide in Amyotrophic Lateral Sclerosis (ALS) - This study is currently recruiting patients (Current: 23 Nov 2006) - Thalidomide (drug)
• A Multicenter, Dose Ranging Safety and Pharmacokinetics Study of Arimoclomol in ALS - This study is no longer recruiting patients (Current: 23 Nov 2006) - arimoclomol
• Amyotrophic Lateral Sclerosis and Frontotemporal Dementia - This study is currently recruiting patients (Current: 23 Nov 2006)
• Collection of Blood Samples for DNA in Motor Neuron Disease - This study is currently recruiting patients (Current: 23 Nov 2006)
• Amyotrophic Lateral Sclerosis (ALS) Veterans Registry - This study is currently recruiting patients (Current: 23 Nov 2006)
• Exposure to Neurotoxins as Risk Factors for ALS - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Study of "Post-Polio Syndrome" - This study has been completed (Current: 23 Nov 2006)
• Brain Function in Primary Lateral Sclerosis and Amyotrophic Lateral Sclerosis - This study is currently recruiting patients (Current: 23 Nov 2006)

Drugs used in Clinical Trials for Amyotrophic lateral sclerosis

The format for each of the following is:

• The drug,
• followed by the name of the trial,
• followed by whether the trial is recruiting patients,
  - The trial may not have started and not yet recruiting, or the trial may have started and do not need any more recruitements, or the trial may be completed.
  - Note**: Please follow the link to determine the current trial status.

ClinicalTrials.gov has listed the following drugs in trials for Amyotrophic lateral sclerosis:

• AVP-923 - Safety/Efficacy of AVP-923 in the Treatment of Emotional Lability (Uncontrolled Crying & Laughing) in Patients With ALS - This study has been completed (Current: 23 Nov 2006)
• Arimoclomol - A Multicenter, Dose Ranging Safety and Pharmacokinetics Study of Arimoclomol in ALS - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Botulinum toxin type B (Myobloc) - Study of Myobloc in the Treatment of Sialorrhea (Drooling) in Patients With Amyotrophic Lateral Sclerosis (ALS) - This study is currently recruiting patients (Current: 23 Nov 2006)
• Ceftriaxone - Clinical Trial Ceftriaxone in Subjects With ALS - This study is currently recruiting patients (Current: 23 Nov 2006)
• Celecoxib - Combination Therapy Selection Trial in Amyotrophic Lateral Sclerosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Coenzyme Q10 - Clinical Trial of High Dose CoQ10 in ALS - This study is currently recruiting patients (Current: 23 Nov 2006)
• Creatine Monohydrate - Creatine for the Treatment of Amyotrophic Lateral Sclerosis - This study has been completed (Current: 23 Nov 2006)
• Creatine Monohydrate - Study of Creatine Monohydrate in Patients With Amyotrophic Lateral Sclerosis - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Creatine - Clinical Trial of Creatine in Amyotrophic Lateral Sclerosis [ALS] - This study has been completed (Current: 23 Nov 2006)
• Creatine - Combination Therapy Selection Trial in Amyotrophic Lateral Sclerosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Creatinine - Clinical Trial of Creatine in Amyotrophic Lateral Sclerosis - This study has been completed (Current: 23 Nov 2006)
• Edaravone (Radicut) - Efficacy and Safety Study of MCI-186 for Treatment of Amyotrophic Lateral Sclerosis (ALS) - This study is currently recruiting patients (Current: 23 Nov 2006)
• Erythropoetin (Epo) - Influence of G-CSF and EPO on Associative Learning and Motor Skills - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Granulocyte - Colony Stimulating Factor (G-Csf) - Influence of G-CSF and EPO on Associative Learning and Motor Skills - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Granulocyte-Colony Stimulating Factor - G-CSF Treatment for Amyotrophic Lateral Sclerosis: A RCT Study Assessing Clinical Response - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Insulin-Like Growth Factor-1 (Igf-I) - Insulin-Like Growth Factor-1 (IGF-1) in Amyotrophic Lateral Sclerosis (ALS) Trial - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Leuprolide - Phase II Study of Leuprolide and Testosterone for Men With Kennedy's Disease or Other Motor Neuron Disease - This study has been completed (Current: 23 Nov 2006)
• Levetiracetam - Levetiracetam for Cramps, Spasticity and Neuroprotection in Motor Neuron Disease - This study is currently recruiting patients (Current: 23 Nov 2006)
• Memantine - Memantine for Disability in Amyotrophic Lateral Sclerosis (MEDALS) - This study is currently recruiting patients (Current: 23 Nov 2006)
• Minocycline - Combination Therapy Selection Trial in Amyotrophic Lateral Sclerosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Minocycline - Minocycline to Treat Amyotrophic Lateral Sclerosis - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Parenteral Drug / 40 mg Glatiramer Acetate - Clinical Trial of Glatiramer Acetate in Amyotrophic Lateral Sclerosis (ALS) - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• R(+) pramipexole dihydrochloride monohydrate - R(+) Pramipexole in Early Amyotrophic Lateral Sclerosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Sodium Phenylbutyrate - Safety Study of Oral Sodium Phenylbutyrate in Subjects With ALS (Amyotrophic Lateral Sclerosis) - This study is currently recruiting patients (Current: 23 Nov 2006)
• Sodium Valproate - Trial of Sodium Valproate in Amyotrophic Lateral Sclerosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• TCH346 - A 12-Week, Multicenter, Safety and Dose-Ranging Study of 3 Oral Doses of TCH346 in Patients With Amyotrophic Lateral Sclerosis - This study has been completed (Current: 23 Nov 2006)
• TCH346 - A Long-Term Extension Study of TCH346 and Placebo Administered Once Daily in Patients With Amyotrophic Lateral Sclerosis(ALS) - This study has been completed (Current: 23 Nov 2006)
• TCH346 - Study Evaluating TCH346 and Placebo Administered Once Daily in Patients With Amyotrophic Lateral Sclerosis (ALS) - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Tamoxifen - Tamoxifen Therapy in Amyotrophic Lateral Sclerosis [ALS] - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Testosterone - Phase II Study of Leuprolide and Testosterone for Men With Kennedy's Disease or Other Motor Neuron Disease - This study has been completed (Current: 23 Nov 2006)
• Thalidomide (drug) - Pilot-Study of Thalidomide in Amyotrophic Lateral Sclerosis (ALS) - This study is currently recruiting patients (Current: 23 Nov 2006)
• Thalidomide - Phase II Study Using Thalidomide for the Treatment of ALS - This study is currently recruiting patients (Current: 23 Nov 2006)
• Vitamin E - Clinical Trial of Vitamin E to Treat Muscular Cramps in Patients With ALS - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• AVP-923 - Safety/Efficacy of AVP-923 in the Treatment of Emotional Lability (Uncontrolled Crying & Laughing) in Patients With ALS - This study has been completed (Current: 23 Nov 2006)
• Arimoclomol - A Multicenter, Dose Ranging Safety and Pharmacokinetics Study of Arimoclomol in ALS - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Botulinum toxin type B (Myobloc) - Study of Myobloc in the Treatment of Sialorrhea (Drooling) in Patients With Amyotrophic Lateral Sclerosis (ALS) - This study is currently recruiting patients (Current: 23 Nov 2006)
• Ceftriaxone - Clinical Trial Ceftriaxone in Subjects With ALS - This study is currently recruiting patients (Current: 23 Nov 2006)
• Celecoxib - Combination Therapy Selection Trial in Amyotrophic Lateral Sclerosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Coenzyme Q10 - Clinical Trial of High Dose CoQ10 in ALS - This study is currently recruiting patients (Current: 23 Nov 2006)
• Creatine Monohydrate - Creatine for the Treatment of Amyotrophic Lateral Sclerosis - This study has been completed (Current: 23 Nov 2006)
• Creatine Monohydrate - Study of Creatine Monohydrate in Patients With Amyotrophic Lateral Sclerosis - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Creatine - Clinical Trial of Creatine in Amyotrophic Lateral Sclerosis [ALS] - This study has been completed (Current: 23 Nov 2006)
• Creatine - Combination Therapy Selection Trial in Amyotrophic Lateral Sclerosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Creatinine - Clinical Trial of Creatine in Amyotrophic Lateral Sclerosis - This study has been completed (Current: 23 Nov 2006)
• Edaravone (Radicut) - Efficacy and Safety Study of MCI-186 for Treatment of Amyotrophic Lateral Sclerosis (ALS) - This study is currently recruiting patients (Current: 23 Nov 2006)
• Erythropoetin (Epo) - Influence of G-CSF and EPO on Associative Learning and Motor Skills - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Granulocyte - Colony Stimulating Factor (G-Csf) - Influence of G-CSF and EPO on Associative Learning and Motor Skills - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Granulocyte-Colony Stimulating Factor - G-CSF Treatment for Amyotrophic Lateral Sclerosis: A RCT Study Assessing Clinical Response - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Insulin-Like Growth Factor-1 (Igf-I) - Insulin-Like Growth Factor-1 (IGF-1) in Amyotrophic Lateral Sclerosis (ALS) Trial - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Leuprolide - Phase II Study of Leuprolide and Testosterone for Men With Kennedy's Disease or Other Motor Neuron Disease - This study has been completed (Current: 23 Nov 2006)
• Levetiracetam - Levetiracetam for Cramps, Spasticity and Neuroprotection in Motor Neuron Disease - This study is currently recruiting patients (Current: 23 Nov 2006)
• Memantine - Memantine for Disability in Amyotrophic Lateral Sclerosis (MEDALS) - This study is currently recruiting patients (Current: 23 Nov 2006)
• Minocycline - Combination Therapy Selection Trial in Amyotrophic Lateral Sclerosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Minocycline - Minocycline to Treat Amyotrophic Lateral Sclerosis - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Parenteral Drug / 40 mg Glatiramer Acetate - Clinical Trial of Glatiramer Acetate in Amyotrophic Lateral Sclerosis (ALS) - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• R(+) pramipexole dihydrochloride monohydrate - R(+) Pramipexole in Early Amyotrophic Lateral Sclerosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Sodium Phenylbutyrate - Safety Study of Oral Sodium Phenylbutyrate in Subjects With ALS (Amyotrophic Lateral Sclerosis) - This study is currently recruiting patients (Current: 23 Nov 2006)
• Sodium Valproate - Trial of Sodium Valproate in Amyotrophic Lateral Sclerosis - This study is currently recruiting patients (Current: 23 Nov 2006)
• TCH346 - A 12-Week, Multicenter, Safety and Dose-Ranging Study of 3 Oral Doses of TCH346 in Patients With Amyotrophic Lateral Sclerosis - This study has been completed (Current: 23 Nov 2006)
• TCH346 - A Long-Term Extension Study of TCH346 and Placebo Administered Once Daily in Patients With Amyotrophic Lateral Sclerosis(ALS) - This study has been completed (Current: 23 Nov 2006)
• TCH346 - Study Evaluating TCH346 and Placebo Administered Once Daily in Patients With Amyotrophic Lateral Sclerosis (ALS) - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Tamoxifen - Tamoxifen Therapy in Amyotrophic Lateral Sclerosis [ALS] - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Testosterone - Phase II Study of Leuprolide and Testosterone for Men With Kennedy's Disease or Other Motor Neuron Disease - This study has been completed (Current: 23 Nov 2006)
• Thalidomide (drug) - Pilot-Study of Thalidomide in Amyotrophic Lateral Sclerosis (ALS) - This study is currently recruiting patients (Current: 23 Nov 2006)
• Thalidomide - Phase II Study Using Thalidomide for the Treatment of ALS - This study is currently recruiting patients (Current: 23 Nov 2006)
• Vitamin E - Clinical Trial of Vitamin E to Treat Muscular Cramps in Patients With ALS - This study is not yet open for patient recruitment (Current: 23 Nov 2006)

The trial data on this page has been sourced from

• The U.S. National Library of Medicine (NLM) together with ClinicalTrials.gov

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