Diseases » Anal Cancer » Clinical Trials

Clinical Trials for Anal Cancer

Clinical trials are research studies conducted in an effort to improve overall patient health and care. Each trial involves running supervised tests to determine the effectiveness and safety of new drugs, procedures and/or devices with the aim of answering scientific questions about a disease or condition. Risks and side-effects are also evaluated during these trials with results ranging from being unpleasant, with side effects such as headaches, to more serious or even life-threatening risks. A clinical trial may be separated into phases, or steps, with each step designed to answer a separate research question. This maybe reflected in the trial name.

A brief description of each phase:

Phase I: Usually designed to evaluate safety, determine a safe dosage range, and identify side effects on a small group of patients.
Phase II: If Phase I is successful, the trial is then repeated with a larger group to further evaluate its effect and safety.
Phase III: Trials are conducted on an ever larger group and are compared with the best current treatment while gathering more information on effect and safety.
Phase IV: These studies monitor long-term side effects after the treatment has been marketed.

Clinical Trials data for Anal Cancer is grouped into the following categories:-

View by trial name

View by drugs used in Anal Cancer clinical trials

Clinical Trials by trial name

The format for each of the following is:

The name of the trial,
followed by whether the trial is recruiting patients,
- The trial may not have started and not yet recruiting, or the trial may have started and do not need any more recruitements, or the trial may be completed.
- Note**: Please follow the link to determine the current trial status.
followed by a list of drug/s, if any, used in the trial

ClinicalTrials.gov has listed the following trials for Anal Cancer:

Chemoprevention of Anal Neoplasia Arising Secondary to Anogenital Human Papillomavirus Infection in Persons With HIV Infection. - This study has been completed (Current: 23 Nov 2006) - Isotretinoin,Interferon alfa-2a
A Study of Anal Cancer Development in HIV Infected People - This study is no longer recruiting patients (Current: 23 Nov 2006)
Chemotherapy Plus Radiation Therapy in Treating Patients With Stage II or Stage III Anal Cancer - This study is no longer recruiting patients (Current: 23 Nov 2006) - cisplatin,fluorouracil,mitomycin
Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Stage II or Stage III Anal Cancer - This study is no longer recruiting patients (Current: 23 Nov 2006) - cisplatin,fluorouracil
Vaccine Therapy in Treating Patients With Advanced or Recurrent Cancer - This study is no longer recruiting patients (Current: 23 Nov 2006) - human papillomavirus 16 E6 peptide,human papillomavirus 16 E7 peptide
Radiation Therapy Plus Fluorouracil With or Without Additional Chemotherapy in Treating Patients With Primary Anal Cancer - This study is currently recruiting patients (Current: 23 Nov 2006) - cisplatin,fluorouracil,mitomycin
SGN-00101 in Preventing Anal Cancer in Patients With HIV Who Have Anal Neoplasia - This study has been completed (Current: 23 Nov 2006) - SGN-00101
Anal Sphincter Prosthesis in Treating Patients Who Are Undergoing Surgery for Anal or Rectal Cancer - This study is currently recruiting patients (Current: 23 Nov 2006)
Infrared Coagulation in Preventing Anal Cancer in Patients With HIV Who Have Anal Neoplasia - This study has been completed (Current: 23 Nov 2006)
Radiation Therapy, Mitomycin, and Either Fluorouracil or Cisplatin in Treating Patients With Locally Advanced Anal Cancer - This study is currently recruiting patients (Current: 23 Nov 2006) - cisplatin,fluorouracil,mitomycin
Octreotide in Preventing or Reducing Diarrhea in Patients Receiving Chemoradiotherapy for Anal or Rectal Cancer - This study is no longer recruiting patients (Current: 23 Nov 2006) - octreotide
Capecitabine, Oxaliplatin, and Radiation Therapy in Treating Patients With Stage II or Stage III Anal Cancer - This study is currently recruiting patients (Current: 23 Nov 2006) - capecitabine,oxaliplatin
Biobank Anus Carcinoma: Storing Blood and Protein of Patients With Anus Cancer - This study is currently recruiting patients (Current: 23 Nov 2006)
Screening for HIV-Associated Anal Cancer - This study is currently recruiting patients (Current: 23 Nov 2006)
Molecular Genetic and Pathological Studies of Anal Tumors - This study is currently recruiting patients (Current: 23 Nov 2006)
Image Fusion PET, CT and 3D-Ultrasound Examinations - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
Cetuximab, Cisplatin, Fluorouracil, and Radiation Therapy in Treating Patients With Stage I, Stage II, or Stage III Anal Cancer - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - cetuximab,cisplatin,fluorouracil
Cisplatin, Fluorouracil, Cetuximab, and Radiation Therapy in Treating Patients With HIV and Stage I, Stage II, or Stage III Anal Cancer - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - cetuximab,cisplatin,fluorouracil
Chemoradtx Nausea/Emesis: Quality of Life - This study is currently recruiting patients (Current: 23 Nov 2006)

Drugs used in Clinical Trials for Anal Cancer

The format for each of the following is:

The drug,
followed by the name of the trial,
followed by whether the trial is recruiting patients,
- The trial may not have started and not yet recruiting, or the trial may have started and do not need any more recruitements, or the trial may be completed.
- Note**: Please follow the link to determine the current trial status.

ClinicalTrials.gov has listed the following drugs in trials for Anal Cancer: