Inheritance and Genetics of Androgen Insensitivity Syndrome
Inheritance of Androgen Insensitivity Syndrome:
X-linked recessive diseases are usually inherited by males from their mother. Rare cases of sporadic genetic disease can also occur. See inheritance of x-linked recessive diseases.
Androgen Insensitivity Syndrome: Inheritance and Genetics Details
Inheritance properties of Androgen Insensitivity Syndrome:
Disease inherited from:
Usually inherited by males from their mother who is a carrier; see inheritance of x-linked recessive diseases.
Gender bias in inheritance:
Males only get x-linked recessive diseases; females are carriers.
Inheritance Patterns
Inheritance odds for Androgen Insensitivity Syndrome:
Overall odds of inheritance:
Usually inherited by males from their mother who is a carrier; see inheritance of x-linked recessive diseases.
Sibling of diseased child odds of inheriting disease:
About 50% for a second child if one (male) child already has the x-linked recessive disease.
Mother to son inheritance odds:
50% disease, 50% disease-free, males cannot be a carrier of an x-linked recessive disease.
Father to son inheritance odds:
0% chance usually for x-linked recessive diseases.
Mother to daughter inheritance odds:
0% disease; 50% female carrier, 50% chance neither affected nor carrier.
Father to daughter inheritance odds:
0% chance of x-linked recessive disease; 100% chance the female child is a carrier.
Inheritance Features
Inheritance features for Androgen Insensitivity Syndrome:
Sporadic form of disease possible?:
Yes, requires single mutation for x-linked recessive disease.
Milder form of disease possible in females?:
Yes, females have mild disease for some x-linked recessive diseases.
About inheritance and genetics:
Inheritance of Androgen Insensitivity Syndrome refers to whether the condition is inherited
from your parents or "runs" in families.
The level of inheritance of a condition depends
on how important genetics are to the disease.
Strongly genetic diseases are usually inherited,
partially genetic diseases are sometimes inherited,
and non-genetic diseases are not inherited.
For general information, see Introduction to Genetics.
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