Prevalence and Incidence of Angioedema

Ophanet, who are a consortium of European partners, currently defines a condition rare when if affects 1 person per 2,000. They list Angioedema as a "rare disease". More information about Angioedema is available from Orphanet

Angioedema Prevalence: Book Excerpts

• Causes and incidence - Urticaria and angioedema
• Urticaria - epidemiology - Urticaria

Prevalence/Incidence of Angioedema: Online Medical Books

16 MEDICAL BOOKS ONLINE! Review excerpts from medical books online, free, without registration, for more information about the prevalence and/or incidence of Angioedema.

Urticaria and angioedema: Causes and incidence
(Professional Guide to Diseases (Eighth Edition))

Urticaria and angioedema are common allergic reactions that may occur in 20% of the general population. The causes of these reactions include allergy to drugs, foods, insect bites and stings and, occasionally, inhalant allergens (animal dander and cosmetics) that provoke an immunoglobulin (Ig) E-mediated response to protein allergens. However, certain drugs may cause urticaria without an IgE response. When urticaria and angioedema are part of an anaphylactic reaction, they almost always persist long after the systemic response has subsided. This occurs because circulation to the skin is the last to be restored after an allergic reaction, which results in slow histamine reabsorption at the reaction site.

Nonallergic urticaria and angioedema are also related to histamine release. External physical stimuli, such as cold (usually in young adults), heat, water, or sunlight, may also provoke urticaria and angioedema. Dermographism urticaria, which develops after stroking or scratching of the skin, occurs in as much as 20% of the population. Such urticaria develops with varying pressure, usually under tight clothing, and is aggravated by scratching.

Several different mechanisms and underlying disorders may provoke urticaria and angioedema. These include IgE-induced release of mediators from cutaneous mast cells; binding of IgG or IgM to antigen, resulting in complement activation; and such disorders as localized or secondary infections (such as respiratory infection), neoplastic diseases (such as Hodgkin’s disease), connective tissue diseases (such as systemic lupus erythematosus), collagen vascular diseases, and psychogenic diseases.

» READ BOOK EXCERPT ONLINE »

Source: Professional Guide to Diseases (Eighth Edition), 2005

Urticaria: Urticaria - epidemiology
(The 5-Minute Pediatric Consult)

• Female:Male ratio of 3:2
• No variation in race

Urticaria - incidence

Lifetime incidence of 15–25%

» READ BOOK EXCERPT ONLINE »

Source: The 5-Minute Pediatric Consult, 2008

About prevalence and incidence statistics:

The term 'prevalence' of Angioedema usually refers to the estimated population of people who are managing Angioedema at any given time. The term 'incidence' of Angioedema refers to the annual diagnosis rate, or the number of new cases of Angioedema diagnosed each year. Hence, these two statistics types can differ: a short-lived disease like flu can have high annual incidence but low prevalence, but a life-long disease like diabetes has a low annual incidence but high prevalence. For more information see about prevalence and incidence statistics.

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