Glossary for Ankylosing Spondylitis

• Adolescent conditions: Symptoms that are evident due to puberty
• Alkaptonuria: A rare disorder where the abnormal accumulation of a particular acid (homogentisic acid) in the body causes connective tissue and bone damage. This damage gives tissues a dark or bluish discoloration.
• Angelman syndrome: A rare genetic disorder characterized by a puppet-like gait, fits of laughter and characteristic facial features.
• Ankylosing Spondylitis: Inflammation of spinal joints similar to rheumatoid arthritis.
• Aortic Aneurysm, Thoracic: Bulging and weakness of the aorta in the area of the chest. The condition is life-threatening as death can occur rapidly if the aneurysm bursts.
• Aortic valve incompetence: A condition characterized by an inability of the aortic valve to function effectively
• Arthritis: General name for any type of joint inflammation, but often means age-related osteoarthritis.
• Autoimmune diseases: A group of disorders in which the primary cause is the an inflammatory reaction caused by the body's own immune system attacking tissues
• Cauda equina syndrome: Is a neurological syndrome which occurs when a vertebral disc protrudes and compresses the spinal cord.
• Chest pain: Pain in the chest area.
• Enthesopathy: A disease process occurring at locations where tendons and ligaments attach to bone.
• Fatigue: Excessive tiredness or weakness.
• Fever: Elevation of the body temperature above the normal 37 degrees celsius
• Hyperparathyroidism: Increased secretion of parathyroid hormone from the parathyroid glands.
• Inflammatory bowel disease: Any type of digestive condition caused by bowel inflammation.
• Juvenile Rheumatoid Arthritis: Chronic arthritis affecting children and teens
• Lower back pain: Pain in the lower back region
• Marfan syndrome: A genetic connective tissue disorder involving a defect of chromosome 15q21.1 which affects the production of the fibrillin needed to make connective tissue.
• Osteoarthritis: Osteoarthritis is a chronic condition characterised by mechanical disrturbances due to degradation of joints. It is the most common form of arthritis, and the leading cause of chronic disability.
• Osteoporosis: Bone thinning and weakening from bone calcium depletion.
• Psoriatic Arthritis: Psoriatic arthritis is a chronic disease characterized by inflammation of the skin (psoriasis) and joints (arthritis). Psoriatic arthritis is said to be a seronegative spondyloarthropathy and therefore occurs more commonly in patients with tissue type HLA-B27.
• Reactive arthritis: The inflammation of a joint
• Reiter’s syndrome: A form of reactive arthritis characterized by arthritis, urethritis, conjunctivitis and skin lesions.
• Rheumatic conditions: Any condition that affects ones joints
• Rheumatoid arthritis: Autoimmune form of arthritis usually in teens or young adults.
• Sciatica: Sciatica is a set of symptoms including pain that may be caused by general compression and/or irritation of one of five nerve roots that give rise to the sciatic nerve, or by compression or irritation of the sciatic nerve itself.
• Seronegative Arthritis: Classification given to the group of joint conditions with similar features to rheumatoid arthritis, but affecting different joints and lacking the specific autoantibodies used to identify rheumatoid arthritis
• Seronegative spondyloarthropathy: Spondyloarthropathy that is negative to rheumatoid facotr
• Spinal conditions: Any condition that affects the spine
• Spinal stenosis: Narrowing of the spinal cavity around the spinal cord.
• Spine symptoms: Symptoms affecting the spine
• Spondylitis: Inflammation of one or multiple bony vertebrae of the spine
• Stiff back: Reduced mobility or movement of the back
• Ulcerative colitis: Ulcerative colitis (Colitis ulcerosa, UC) is a form of inflammatory bowel disease (IBD). Ulcerative colitis is a form of colitis, a disease of the intestine, specifically the large intestine or colon, that includes characteristic ulcers, or open sores, in the colon.
• Uveitis: A condition which is characterised by the inflammation of the uvea of the eye

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