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Arthritis – Single Joint

Arthritis – Single Joint: Excerpt from In A Page: Pediatric Signs and Symptoms

Arthritis in a single joint, or monoarthritis, is a difficult diagnostic challenge, because any disorder affecting joints may initially present as monoarthritis. After establishing that the arthritis is truly monoarticular, the most important considerations are septic joint and trauma. Joint pain may arise not only from joint itself but from adjacent bone, ligaments, tendons, bursae, or soft tissues. Presence of effusion usually indicates intra-articular pathology, although osteomyelitis, fractures, or tumors may cause effusion as well.

Differential Diagnosis

  • Septic arthritis
    –Rapid diagnosis critical: Untreated septic arthritis causes irreversible joint and bone destruction
    –Usually presents hyperacutely with very tender, swollen, warm, red joint with severely restricted range of motion
    –Usual pathogens: Haemophilus influenzae type b, Staphylococcus aureus, group B strep in neonates, and Neisseria gonorrhoeae in adolescents; fungal and mycobacterial arthritis are seen rarely, may have chronic course
    • Lyme arthritis
      –Second most common manifestation of Lyme disease (after erythema migrans)
      –Monoarthritis of a knee occurs in about two-thirds of children with Lyme disease
    • Reactive arthritis
      –Probably the most common etiology of childhood rheumatic diseases
      –Transient sterile arthritis following a bacterial GI infection
      –Usually full resolution, but a few children have a chronic course
  • Trauma, overuse, fracture
    –Often acute onset with significant pain
  • Malignancy such as leukemia, neuroblastoma and osteogenic sarcoma
  • Pauciarticular juvenile rheumatoid arthritis (JRA)
  • Spondyloarthropathies (SpA)
  • Congenital hip dysplasia
  • Slipped capital femoral epiphysis (SCFE)
    –Most common adolescent hip disorder
    –Separation of the femoral growth plate
    –More common in obese males
    • Spontaneous osteonecrosis of the joint
      –Mostly in hip (Legg-Calvé-Perthes disease), shoulder, and knee
      –More common in males
    • Internal structural abnormality
      –Discoid meniscus, osteochondritis dissecans, synovial chondromatosis
  • Hemarthrosis due to trauma, bleeding disorder such as hemophilia, or benign tumors such as hemangiomas and pigmented villonodular synovitis
  • Periodic fever syndromes such as familial Mediterranean fever

Workup and Diagnosis

  • History
    –Acute or chronic
    –Mechanical (pain worsens with activities, improves with rest, and usually involves weight-bearing joints)
    –Inflammatory (waxing and waning, symptoms unrelated to use, morning stiffness)
    –History of trauma
    –Night-time symptoms
    –Attempted treatments
    –Systemic symptoms: Fever, rash, pain, fatigue
    –Past medical history: Birth history, existing medical conditions, surgeries, broken bones, growth and development, medications
    –Unusual exposures such as tick bites
    • Physical exam
      –Vital signs, including growth parameters
      –Musculoskeletal exam for swelling, tenderness, warmth, redness, range of motion, asymmetry
      –Muscle strength and neurologic exam (tone, sensory and reflexes)
      –Lympadenopathy, organomegaly, rash, systemic symptoms
  • Radiologic evaluation may include X-ray, US, MRI, and bone scan to evaluate for fracture, infection, tenosynovitis, or internal derangements
  • Lab investigation may include CBC, ESR, CRP, examination of synovial fluid, viral titers (parvovirus), Lyme titers, RF, and ANA

Treatment

  • If septic arthritis is a possibility, broad-spectrum antibiotic treatment should be started immediately
  • Fractures and most internal derangements require orthopedics involvement
  • Appropriate referral and treatment for malignancy
  • JRA and SpA are usually treated with NSAIDs initially, DMARDs (e.g., sulfasalazine and methotrexate) and biologics (e.g., TNF blockers) are added depending on the degree of inflammation and the response of individual patient
  • Supportive therapy such as PT and OT to increase range of motion and strength; insoles to correct leg length discrepancy
  • Psychosocial support, especially with chronic arthritis

Book Source Details

  • Book Title: In A Page: Pediatric Signs and Symptoms
  • Author(s): Jonathan E. Teitelbaum, Kathleen O. Deantonis, Scott Kahan
  • Year of Publication: 2007
  • Copyright Details: In A Page: Pediatric Signs and Symptoms, Copyright © 2007 Lippincott Williams & Wilkins.

More About Arthritis

More Medical Textbooks Online about Arthritis

Review other book chapters online related to Arthritis:

Medical Books Excerpts
  • BACK PAIN
  • "Algorithmic Diagnosis of Symptoms and Signs" (2003)
  • BREAST PAIN
  • "Algorithmic Diagnosis of Symptoms and Signs" (2003)
  • CHEST PAIN
  • "Algorithmic Diagnosis of Symptoms and Signs" (2003)
  • EYE PAIN
  • "Algorithmic Diagnosis of Symptoms and Signs" (2003)
  • FACE PAIN
  • "Algorithmic Diagnosis of Symptoms and Signs" (2003)
  • FLANK PAIN
  • "Algorithmic Diagnosis of Symptoms and Signs" (2003)
  • HEEL PAIN
  • "Algorithmic Diagnosis of Symptoms and Signs" (2003)
  • HIP PAIN
  • "Algorithmic Diagnosis of Symptoms and Signs" (2003)
  • JAW PAIN
  • "Algorithmic Diagnosis of Symptoms and Signs" (2003)
  • KNEE PAIN
  • "Algorithmic Diagnosis of Symptoms and Signs" (2003)
  • Back Pain
  • "In A Page: Pediatric Signs and Symptoms" (2007)
  • Chest Pain
  • "In A Page: Pediatric Signs and Symptoms" (2007)
  • Hip Pain
  • "In A Page: Pediatric Signs and Symptoms" (2007)
  • Knee Pain
  • "In A Page: Pediatric Signs and Symptoms" (2007)
  • ARM PAIN
  • "Differential Diagnosis in Primary Care" (2007)
  • EYE PAIN
  • "Differential Diagnosis in Primary Care" (2007)
  • HIP PAIN
  • "Differential Diagnosis in Primary Care" (2007)
  • Arm pain
  • "Handbook of Signs & Symptoms (Third Edition)" (2006)
  • Back pain
  • "Handbook of Signs & Symptoms (Third Edition)" (2006)
  • Chest pain
  • "Handbook of Signs & Symptoms (Third Edition)" (2006)
  • Eye pain
  • "Handbook of Signs & Symptoms (Third Edition)" (2006)
  • Flank pain
  • "Handbook of Signs & Symptoms (Third Edition)" (2006)
  • Jaw pain
  • "Handbook of Signs & Symptoms (Third Edition)" (2006)
  • Leg pain
  • "Handbook of Signs & Symptoms (Third Edition)" (2006)
  • Neck pain
  • "Handbook of Signs & Symptoms (Third Edition)" (2006)
  • Rectal pain
  • "Handbook of Signs & Symptoms (Third Edition)" (2006)
  • Throat pain
  • "Handbook of Signs & Symptoms (Third Edition)" (2006)
  • Back Pain
  • "A Pocket Manual of Differential Diagnosis" (1999)
  • Chest Pain
  • "A Pocket Manual of Differential Diagnosis" (1999)
  • Arm pain
  • "Professional Guide to Signs & Symptoms (Fifth Edition)" (2006)
  • Back pain
  • "Professional Guide to Signs & Symptoms (Fifth Edition)" (2006)
  • Chest pain
  • "Professional Guide to Signs & Symptoms (Fifth Edition)" (2006)
  • Facial pain
  • "Professional Guide to Signs & Symptoms (Fifth Edition)" (2006)
  • Flank pain
  • "Professional Guide to Signs & Symptoms (Fifth Edition)" (2006)
  • Jaw pain
  • "Professional Guide to Signs & Symptoms (Fifth Edition)" (2006)
  • Leg Pain
  • "Professional Guide to Signs & Symptoms (Fifth Edition)" (2006)
  • Neck pain
  • "Professional Guide to Signs & Symptoms (Fifth Edition)" (2006)
  • Rectal pain
  • "Professional Guide to Signs & Symptoms (Fifth Edition)" (2006)
  • Throat pain
  • "Professional Guide to Signs & Symptoms (Fifth Edition)" (2006)
  • Gum swelling
  • "Professional Guide to Signs & Symptoms (Fifth Edition)" (2006)
  • Arthralgia
  • "The 10-Minute Diagnosis Manual: Symptoms and Signs in the Time-Limited Encounter" (2000)
  • Chest Pain, Atypical
  • "The 10-Minute Diagnosis Manual: Symptoms and Signs in the Time-Limited Encounter" (2000)
  • Low Back Pain
  • "The 10-Minute Diagnosis Manual: Symptoms and Signs in the Time-Limited Encounter" (2000)
  • Abdominal Pain
  • "The 10-Minute Diagnosis Manual: Symptoms and Signs in the Time-Limited Encounter" (2000)
  • Calf Pain
  • "The 10-Minute Diagnosis Manual: Symptoms and Signs in the Time-Limited Encounter" (2000)
  • Chronic Pelvic Pain
  • "The 10-Minute Diagnosis Manual: Symptoms and Signs in the Time-Limited Encounter" (2000)
  • Hip Pain
  • "The 10-Minute Diagnosis Manual: Symptoms and Signs in the Time-Limited Encounter" (2000)
  • Knee Pain
  • "The 10-Minute Diagnosis Manual: Symptoms and Signs in the Time-Limited Encounter" (2000)
  • Neck Pain
  • "The 10-Minute Diagnosis Manual: Symptoms and Signs in the Time-Limited Encounter" (2000)
  • Pleuritic Pain
  • "The 10-Minute Diagnosis Manual: Symptoms and Signs in the Time-Limited Encounter" (2000)
  • Shoulder Pain
  • "The 10-Minute Diagnosis Manual: Symptoms and Signs in the Time-Limited Encounter" (2000)
  • Scrotal Pain
  • "The 10-Minute Diagnosis Manual: Symptoms and Signs in the Time-Limited Encounter" (2000)
  • Eye Pain
  • "Field Guide to Bedside Diagnosis" (2007)
  • Abdominal pain
  • "Alarming Signs and Symptoms: Lippincott Manual of Nursing Practice Series" (2007)
  • Back pain
  • "Alarming Signs and Symptoms: Lippincott Manual of Nursing Practice Series" (2007)
  • Chest pain
  • "Alarming Signs and Symptoms: Lippincott Manual of Nursing Practice Series" (2007)
  • Eye pain
  • "Alarming Signs and Symptoms: Lippincott Manual of Nursing Practice Series" (2007)
  • Flank pain
  • "Alarming Signs and Symptoms: Lippincott Manual of Nursing Practice Series" (2007)
  • Jaw pain
  • "Alarming Signs and Symptoms: Lippincott Manual of Nursing Practice Series" (2007)
  • Neck pain
  • "Alarming Signs and Symptoms: Lippincott Manual of Nursing Practice Series" (2007)
  • Scrotal swelling
  • "Alarming Signs and Symptoms: Lippincott Manual of Nursing Practice Series" (2007)
  • Arm pain
  • "Signs & Symptoms: A 2-in-1 Reference for Nurses" (2007)
  • Back pain
  • "Signs & Symptoms: A 2-in-1 Reference for Nurses" (2007)
  • Breast pain
  • "Signs & Symptoms: A 2-in-1 Reference for Nurses" (2007)
  • Chest pain
  • "Signs & Symptoms: A 2-in-1 Reference for Nurses" (2007)
  • Eye pain
  • "Signs & Symptoms: A 2-in-1 Reference for Nurses" (2007)
  • Facial pain
  • "Signs & Symptoms: A 2-in-1 Reference for Nurses" (2007)
  • Flank pain
  • "Signs & Symptoms: A 2-in-1 Reference for Nurses" (2007)
  • Jaw pain
  • "Signs & Symptoms: A 2-in-1 Reference for Nurses" (2007)
  • Leg pain
  • "Signs & Symptoms: A 2-in-1 Reference for Nurses" (2007)
  • Neck pain
  • "Signs & Symptoms: A 2-in-1 Reference for Nurses" (2007)
  • Rectal pain
  • "Signs & Symptoms: A 2-in-1 Reference for Nurses" (2007)
  • Throat pain
  • "Signs & Symptoms: A 2-in-1 Reference for Nurses" (2007)
  • Abdominal Pain
  • "The Diagnostic Approach to Symptoms and Signs in Pediatrics" (2006)
  • Back Pain
  • "The Diagnostic Approach to Symptoms and Signs in Pediatrics" (2006)
  • Chest Pain
  • "The Diagnostic Approach to Symptoms and Signs in Pediatrics" (2006)
  • Arm pain
  • "Nursing: Interpreting Signs and Symptoms" (2007)
  • Back pain
  • "Nursing: Interpreting Signs and Symptoms" (2007)
  • Chest pain
  • "Nursing: Interpreting Signs and Symptoms" (2007)
  • Flank pain
  • "Nursing: Interpreting Signs and Symptoms" (2007)
  • Jaw pain
  • "Nursing: Interpreting Signs and Symptoms" (2007)
  • Leg pain
  • "Nursing: Interpreting Signs and Symptoms" (2007)
  • Neck pain
  • "Nursing: Interpreting Signs and Symptoms" (2007)
  • ARM PAIN
  • "Differential Diagnosis in Primary Care" (2007)
  • EYE PAIN
  • "Differential Diagnosis in Primary Care" (2007)
  • HIP PAIN
  • "Differential Diagnosis in Primary Care" (2007)
 

Copyright notice for book excerpts: Copyright © 2008 Lippincott Williams & Wilkins. All rights reserved.




More About This Book:
Title: In A Page: Pediatric Signs and Symptoms
Authors: Jonathan E. Teitelbaum, Kathleen O. Deantonis, Scott Kahan
Publisher: Lippincott Williams & Wilkins
Copyright: 2007
ISBN: 1-4051-0427-9

 » Next page: Arthritis – Multiple Joints (In A Page: Pediatric Signs and Symptoms)

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