TREATMENTS &
RESEARCH

Search the
latest
treatment
information
here.

Dr. Huntley's
Diagnosis
Checklist

Have a symptom?
See what questions
a doctor would ask.

Diseases » Aspergillosis » Clinical Trials

Clinical Trials for Aspergillosis

Clinical trials are research studies conducted in an effort to improve overall patient health and care. Each trial involves running supervised tests to determine the effectiveness and safety of new drugs, procedures and/or devices with the aim of answering scientific questions about a disease or condition. Risks and side-effects are also evaluated during these trials with results ranging from being unpleasant, with side effects such as headaches, to more serious or even life-threatening risks. A clinical trial may be separated into phases, or steps, with each step designed to answer a separate research question. This maybe reflected in the trial name.

A brief description of each phase:

Phase I: Usually designed to evaluate safety, determine a safe dosage range, and identify side effects on a small group of patients.
Phase II: If Phase I is successful, the trial is then repeated with a larger group to further evaluate its effect and safety.
Phase III: Trials are conducted on an ever larger group and are compared with the best current treatment while gathering more information on effect and safety.
Phase IV: These studies monitor long-term side effects after the treatment has been marketed.

Clinical Trials data for Aspergillosis is grouped into the following categories:-

View by trial name

View by drugs used in Aspergillosis clinical trials

Clinical Trials by trial name

The format for each of the following is:

The name of the trial,
followed by whether the trial is recruiting patients,
- The trial may not have started and not yet recruiting, or the trial may have started and do not need any more recruitements, or the trial may be completed.
- Note**: Please follow the link to determine the current trial status.
followed by a list of drug/s, if any, used in the trial

ClinicalTrials.gov has listed the following trials for Aspergillosis:

An Open Label, Non-Comparative, Multicenter, Phase III Trial of the Efficacy, Safety and Toleration of Voriconazole in the Primary or Secondary Treatment of Invasive Fungal Infections - This study has been completed (Current: 23 Nov 2006)
Comparing the Effectiveness of Fluconazole and a New Medicine (FK463) in Preventing Fungal Infections in Bone Marrow Transplant Patients - This study has been completed (Current: 23 Nov 2006)
Voriconazole to Prevent Systemic Fungal Infections in Children - This study has been completed (Current: 23 Nov 2006)
A Safety & Effectiveness Study of Intravenous Anidulafungin With AmBisome for Treatment of Invasive Aspergillosis (IA). - This study is no longer recruiting patients (Current: 23 Nov 2006) - Anidulafungin,VER002
Inhalation of Liposomal Amphotericin B to Prevent Invasive Aspergillosis - This study is currently recruiting patients (Current: 23 Nov 2006) - nebulised liposomal amphotericin B
Acetato de Caspofungin (Cancidas) in the Treatment of Fungal Infection. - This study is currently recruiting patients (Current: 23 Nov 2006) - Caspofungin
MK0991 in Combination With Standard Antifungal Agent(s) for the Treatment of Salvage Invasive Aspergillosis - This study is no longer recruiting patients (Current: 23 Nov 2006) - MK0991, caspofungin acetate,Comparator: amphotericin B,Comparator: lipid formulation of amphotericin B and/or azole
Micafungin Salvage Mono-Therapy in Invasive Aspergillosis - This study is currently recruiting patients (Current: 23 Nov 2006) - FK463,Micafungin
Voriconazole and Bronchopulmonary Aspergillosis - This study is currently recruiting patients (Current: 23 Nov 2006) - Voriconazole
Voriconazole Vs. Amphotericin B in the Treatment of Invasive Aspergillosis - This study has been completed (Current: 23 Nov 2006)
A Multicenter, Prospective, Randomized, Double-Blind Clinical Trial Comparing Itraconazole Oral Solution in Cyclodextrin to Placebo in the Treatment of Aspergilloma - This study has been completed (Current: 23 Nov 2006) - Itraconazole oral solution
Study of FK463 for the Treatment of Invasive Aspergillosis - This study has been completed (Current: 23 Nov 2006) - FK463
Trial of Micafungin (FK463) in Combination With Liposomal Amphotericin B (AmBisome) for Aspergillosis - This study has been terminated (Current: 23 Nov 2006) - Micafungin (FK463),Liposomal Amphotericin B (AmBisome®)
Documented Candida or Aspergillus Infections in Pediatric Patients - This study is currently recruiting patients (Current: 23 Nov 2006) - MK0991,caspofungin acetate/Duration of Treatment - 7-90 days
To Determine Whether Galactomannan Test Will Help to Detect Fungal Infections Early and Hence Start Treatment Early - This study is currently recruiting patients (Current: 23 Nov 2006)
Study Safety/Efficacy of AmBisome Loading Dose Regimen Versus Standard AmBisome Regimen for Initial Treatment - This study has been completed (Current: 23 Nov 2006) - AmBisome
A Multicentre Randomised Controlled Trial Comparing Two Strategies for the Diagnosis of Invasive Aspergillosis in High-Risk Haematology Patients - This study is currently recruiting patients (Current: 23 Nov 2006)
COMBISTRAT: AmBisome in Combination With Caspofungin for the Treatment of Invasive Aspergillosis - This study has been completed (Current: 23 Nov 2006) - Ambisome,caspofungin
Itraconazole for the Prevention of Fungal Infections in Chronic Granulomatous Disease - This study has been completed (Current: 23 Nov 2006)
Phase I Study of the Safety, Tolerance, and Pharmacokinetics of FK463 in Immunocompromised Children With Fever and Neutropenia - This study has been completed (Current: 23 Nov 2006)
Voriconazole to Treat Fungal Infections - This study has been completed (Current: 23 Nov 2006)
Comparison of 2 Antifungal Treatment (Empirical Versus Pre-Empirical) Strategies in Prolonged Neutropenia - This study is currently recruiting patients (Current: 23 Nov 2006) - Amphotericin B
Historical Control Study of Refractory IFI or Patients Intolerant to Standard Antifungal Therapy in Patients With Invasive Fungal Infections (Study P02387)(COMPLETED) - This study has been completed (Current: 23 Nov 2006)
Prophylaxis With Caspofungin in High-Risk Liver Transplantation - This study is currently recruiting patients (Current: 23 Nov 2006) - Caspofungin
Nebulized Liposomal Amphotericin B (Ambisome) for Prophylaxis of Invasive Pulmonary Aspergillosis - This study is currently recruiting patients (Current: 23 Nov 2006) - liposomal Amphotericine B
Open Label Study of Posaconazole in the Treatment of Invasive Fungal Infections (Study P00041)(COMPLETED) - This study has been completed (Current: 23 Nov 2006) - Posaconazole
PK/PD Study of Posaconazole for Empiric Treatment of Invasive Fungal Infections in Neutropenic Patients or Treatment of Refractory Invasive Fungal Infections (Study P01893)(COMPLETED) - This study has been completed (Current: 23 Nov 2006) - Posaconazole oral suspension
Study of Posaconazole in the Treatment of Invasive Fungal Infections (Study P02095) - This study is currently recruiting patients (Current: 23 Nov 2006) - Posaconazole oral suspension

Drugs used in Clinical Trials for Aspergillosis

The format for each of the following is:

The drug,
followed by the name of the trial,
followed by whether the trial is recruiting patients,
- The trial may not have started and not yet recruiting, or the trial may have started and do not need any more recruitements, or the trial may be completed.
- Note**: Please follow the link to determine the current trial status.

ClinicalTrials.gov has listed the following drugs in trials for Aspergillosis: