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Diseases » Autism » Causes
 

Causes of Autism

List of causes of Autism

Following is a list of causes or underlying conditions (see also Misdiagnosis of underlying causes of Autism) that could possibly cause Autism includes:

Autism Causes: Book Excerpts

Autism as a symptom:

Conditions listing Autism as a symptom may also be potential underlying causes of Autism. Our database lists the following as having Autism as a symptom of that condition:

What causes Autism?

Causes: Autism: Autism has no single cause. Researchers have identified a number of genes that play a role in the disorder. In some children, environmental factors also may play a role in development of the disorder. Studies of people with autism have found abnormalities in several regions of the brain, including the cerebellum, amygdala, hippocampus, septum, and mamillary bodies. Neurons in these regions appear smaller than normal and have stunted nerve fibers, which may interfere with nerve signaling. These abnormalities suggest that autism results from disruption of normal brain development early in fetal development. Other studies suggest that people with autism have abnormalities of serotonin or other signaling molecules in the brain. While these findings are intriguing, they are preliminary and require further study. The early belief that parental practices are responsible for autism has now been disproved. (Source: excerpt from Autism Fact Sheet: NINDS)
Article excerpts about the causes of Autism:
It is generally accepted that autism is caused by abnormalities in brain structures or functions. Using a variety of new research tools to study human and animal brain growth, scientists are discovering more about normal development and how abnormalities occur.

The brain of a fetus develops throughout pregnancy. Starting out with a few cells, the cells grow and divide until the brain contains billions of specialized cells, called neurons. Research sponsored by NIMH and other components at the National Institutes of Health is playing a key role in showing how cells find their way to a specific area of the brain and take on special functions. Once in place, each neuron sends out long fibers that connect with other neurons. In this way, lines of communication are established between various areas of the brain and between the brain and the rest of the body. As each neuron receives a signal it releases chemicals called neurotransmitters, which pass the signal to the next neuron. By birth, the brain has evolved into a complex organ with several distinct regions and subregions, each with a precise set of functions and responsibilities. (Source: excerpt from Autism: NIMH)

Medical news summaries relating to Autism:

The following medical news items are relevant to causes of Autism:

Related information on causes of Autism:

As with all medical conditions, there may be many causal factors. Further relevant information on causes of Autism may be found in:

Causes of Autism: Online Medical Books

16 MEDICAL BOOKS ONLINE! Review excerpts from medical books online, free, without registration, for more information about the causes of Autism.

Autistic disorder: Causes and incidence
(Professional Guide to Diseases (Eighth Edition))

The causes of autistic disorder remain unclear but are thought to include psychological, physiologic, and sociological factors. Much evidence has accumulated to suggest a biological substrate. The parents of a child who’s autistic may appear distant and unaffectionate. However, because children who are autistic are unresponsive or respond with rigid, screaming resistance to touch and attention, parental remoteness may be merely a frustrated, helpless reaction to this disorder, not its cause.

Some children who are autistic show abnormal but nonspecific EEG findings that suggest brain dysfunction, possibly resulting from trauma, disease, or a structural abnormality. Autistic disorder has also been associated with maternal rubella, untreated phenylketonuria, tuberous sclerosis, anoxia during birth, encephalitis, infantile spasms, and fragile X syndrome. Studies have established a link with abnormalities in neurotransmitters, including (in some cases) increased dopamine and increased serotonin. There appears to be a genetic component as well; between 2% and 4% of siblings of those with autism also had autistic disorders at a rate higher than the general population.

Autistic disorder is rare, affecting 4 to 5 children per 10,000 births. It affects three to four times more boys than girls.

» READ BOOK EXCERPT ONLINE »

Source: Professional Guide to Diseases (Eighth Edition), 2005

Autistic disorder: Causes
(Handbook of Diseases)

Autistic disorder is thought to result from a combination of psychological, physiologic, and sociological factors. The parents of an autistic child may appear distant and unaffectionate. However, because autistic children are unresponsive or respond with rigid, screaming resistance to touch and attention, parental remoteness may be merely a frustrated, helpless reaction to this disorder, not its cause.

Some autistic children show abnormal but nonspecific EEG findings that suggest brain dysfunction, possibly resulting from trauma, disease, or a structural abnormality. Autistic disorder also has been associated with maternal rubella, untreated phenylketonuria, tuberous sclerosis, anoxia during birth, encephalitis, infantile spasms, and fragile syndrome X.

» READ BOOK EXCERPT ONLINE »

Source: Handbook of Diseases, 2003


 » Next page: Risk Factors for Autism

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