Treatments for Autoimmune Lymphoproliferative Syndrome
Autoimmune Lymphoproliferative Syndrome: Is the Diagnosis Correct?
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Discussion of treatments for Autoimmune Lymphoproliferative Syndrome:
Steroids are
the first line of treatment for autoimmune episodes, like hemolytic anemia
and
ITP. One common steroid is prednisone. It is often given for
a short time, but sometimes it is needed for longer periods. When
prednisone is not enough to treat the episode, other drugs, such as Imuran
and cyclosporin, may also be prescribed. Steroids have saved lives and
have dramatically reduced the complications in some people with ALPS.
However, like all treatments, steroids have some disadvantages, so they
should not be used too much or for too long. (Source: excerpt from
Autoimmune Lymphoproliferative Syndrome (ALPS): NIAID)
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Book Excerpts: Treatment of Autoimmune Lymphoproliferative Syndrome
Treatments of Autoimmune Lymphoproliferative Syndrome: Online Medical Books
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Lymphadenopathy:
Treatment
(In a Page: Signs and Symptoms)
-
Viral infections require supportive therapy in most cases
-
Bacterial, parasitic, and fungal infections are usually treated with appropriate antibiotics, antiparasitics or antifungals, respectively
-
Offending medication should be removed when possible
-
Malignancies must be identified, staged, and treated as appropriate with chemotherapy, radiation, and/or resection as per the established oncology protocol
» READ BOOK EXCERPT ONLINE »
Source: In a Page: Signs and Symptoms, 2004
Lymphadenopathy:
Treatment
(In A Page: Pediatric Signs and Symptoms)
-
Mild adenopathy with associated viral/URI symptoms
–Observation and recheck in 1–2 weeks
–Malignancy-associated adenopathy can sometimes wax
and wane (especially Hodgkin disease) and appear to improve with antibiotics
–TB nodes may be firm, matted, fixed, and nontender
-
Erythematous, warm, tender nodes
–Trial of oral antibiotics for staph/strep
-
Inflamed/fluctuant lesions: Referral for I&D
-
Refer to pediatric hematologist/oncologist
–Nodes that fail to resolve over 6 weeks
–Nodes that increase in size over 2 weeks
–Firm, matted nodes
–Supraclavicular nodes
–Nodes that generalize to two or more noncontiguous
groups or more than two contiguous groups
-
CBC with differential, CXR before biopsy
» READ BOOK EXCERPT ONLINE »
Source: In A Page: Pediatric Signs and Symptoms, 2007
Chronic fatigue and immune dysfunction syndrome:
Treatment
(Handbook of Diseases)
Treatment is aimed at the cause, if one can be found. Supportive therapy includes an anti-inflammatory, an antihistamine, and rest.
Treatment of symptoms may include a tricyclic antidepressant (doxepin), a histamine2-blocker (cimetidine), and an anxiolytic (alprazolam). In some patients, avoidance of environmental irritants and certain foods may help to relieve symptoms.
Experimental treatments include the antiviral acyclovir and selected immunomodulators, such as I.V. gamma globulin, ampligen, and transfer factor.
» READ BOOK EXCERPT ONLINE »
Source: Handbook of Diseases, 2003
Lymphadenopathy:
Patient counseling
(Signs & Symptoms: A 2-in-1 Reference for Nurses)
Explain the importance of avoiding crowds and washing hands properly to prevent infection. Teach the patient the signs and symptoms of infection he needs to report to the health care provider. If isolation is required, explain its purpose and associated interventions to the patient and his family. Encourage the patient to eat a healthy diet and get plenty of rest.
» READ BOOK EXCERPT ONLINE »
Source: Signs & Symptoms: A 2-in-1 Reference for Nurses, 2007
Lymphadenopathy:
Nursing considerations
(Nursing: Interpreting Signs and Symptoms)
▪ If the patient is uncomfortable, provide an antipyretic, tepid sponge bath, or a hypothermia blanket.
▪ Expect to obtain blood for routine blood work, platelet and white blood cell counts, liver and renal function studies, erythrocyte sedimentation rate, and blood cultures.
▪ Prepare the patient for other diagnostic tests, such as chest X-ray, computed tomography, liver and spleen scan, lymph node biopsy, or lymphography, to visualize the lymphatic system.
▪ If tests reveal infection, check your facility's policy regarding infection control and isolation precautions.
Patient teaching
▪ Explain to the patient all diagnostic tests or procedures.
▪ Teach the patient ways to prevent infection.
▪ Explain the signs and symptoms of infection the patient should report.
▪ Explain the reasons for any isolation precautions.
▪ Stress the importance of a healthy diet and rest.
» READ BOOK EXCERPT ONLINE »
Source: Nursing: Interpreting Signs and Symptoms, 2007
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