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Article title: Amebiasis: DPD
Conditions: Amebiasis
Source: DPD
Amebiasis is a disease caused by a one-celled parasite called Entamoeba histolytica (ent-a-ME-ba his-to-LI-ti-ka).
Although anyone can have this disease, it is most common in people who live in developing
countries that have poor sanitary conditions. In the United States, amebiasis is most often found
in immigrants from developing countries. It also is found in people who have traveled to
developing countries and in people who live in institutions that have poor sanitary conditions.
Men who have sex with men can become infected and can get sick from the infection, but they
often do not have symptoms.
On average, about one in 10 people who are infected with
E. histolytica becomes sick from the infection. The symptoms often are quite mild and can include loose stools, stomach pain, and
stomach cramping. Amebic dysentery is a severe form of amebiasis associated with stomach
pain, bloody stools, and fever. Rarely, E. histolytica invades the liver and forms an abscess.
Even less commonly, it spreads to other parts of the body, such as the lungs or brain.
Usually 1 to 4 weeks later but sometimes more quickly or more slowly.
See your health care provider.
Your health care provider will ask you to submit stool samples. Because
E. histolytica is not always found in every stool sample, you may be asked to submit several stool samples from
several different days.
Diagnosis of amebiasis can be very difficult. One problem is that other parasites and cells can
look very similar to E. histolytica when seen under a microscope. Therefore, sometimes people
are told that they are infected with E. histolytica even though they are not.
Entamoeba histolytica and another amoeba, Entamoeba dispar, which is about 10 times more common, look the same when seen under a microscope. Unlike infection with
E. histolytica, which sometimes makes people sick, infection with E. dispar never makes people sick and therefore does not need
to be treated.
If you have been told that you are infected with E. histolytica but you are feeling fine, you might
be infected with E. dispar instead. Unfortunately, most laboratories do not yet have the tests that
can tell whether a person is infected with E. histolytica or with E. dispar. Until these tests become more widely available, it usually is best to assume that the parasite is
E. histolytica.
A blood test is also available. However, the test is recommended only when your health care
provider thinks that your infection has invaded the wall of the intestine (gut) or some other
organ of your body, such as the liver. One problem is that the blood test may still be positive if
you had amebiasis in the past, even if you are no longer infected now.
Several antibiotics are available to treat amebiasis. Treatment must be prescribed by a physician. You will be treated with only one antibiotic if your E. histolytica infection has not made you sick. You probably will be treated with two antibiotics (first one and then the other) if your infection has made you sick.
Yes. However, the risk of spreading infection is low if the infected person is treated with
antibiotics and practices good personal hygiene. This includes thorough hand washing with soap
and water after using the toilet, after changing diapers, and before handling food.
Ravdin JI. Amebiasis.
Clin Infect Dis 1995;20:1453-66.
This fact sheet is for information only and is not meant to be used for self-diagnosis or as a substitute for consultation with a health care provider. If you have any questions about the disease described above or think that you may have a parasitic infection, consult a health care provider.
» Next page: Amyloidosis and Kidney Disease: NIDDK
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