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B-cell lymphomas is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH). This means that B-cell lymphomas, or a subtype of B-cell lymphomas, affects less than 200,000 people in the US population.
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The cause of non-Hodgkin's lymphoma is unknown, although some theories suggest a viral source. Since the early 1970s, the incidence of these lymphomas has increased more than 80%, with about 53,000 new cases appearing annually in the United States. The reason for the increase is unknown, although it has been partly attributed to acquired immunodeficiency syndrome. Non-Hodgkin's lymphomas are two to three times more common in males than in females and occur in all age-groups. Compared to Hodgkin's disease, they occur about one to three times more often and cause twice as many deaths in children younger than age 15. Incidence rises with age (median age is 50). These lymphomas seem linked to certain races and ethnic groups, with increased incidence in whites and people of Jewish ancestry.
Source: Professional Guide to Diseases (Eighth Edition), 2005
The term 'prevalence' of B-cell lymphomas usually refers to the estimated population of people who are managing B-cell lymphomas at any given time. The term 'incidence' of B-cell lymphomas refers to the annual diagnosis rate, or the number of new cases of B-cell lymphomas diagnosed each year. Hence, these two statistics types can differ: a short-lived disease like flu can have high annual incidence but low prevalence, but a life-long disease like diabetes has a low annual incidence but high prevalence. For more information see about prevalence and incidence statistics.
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