DIZZINESS
DIZZINESS: Excerpt from Differential Diagnosis in Primary Care
Dizziness may mean true vertigo, which is a hallucination of movement
of the patient or his environment, or lightheadedness, which is a feeling
that one is going to faint (and sometimes does). The causes of
lightheadedness are developed under the section on syncope .
The diagnostic approach to dizziness or true vertigo uses anatomy,
beginning with the external ear and working inwards toward the middle ear,
labyrinth, auditory artery and nerve, and vesticular nuclei in the
brainstem. Impacted wax or other foreign bodies in the external ear
may cause vertigo. Otitis media, especially when it invades the mastoid or
petrous bone, is the most important cause of vertigo in the middle ear. One
should not forget serous otitis media from allergies or upper respiratory
infections (URIs). If the drum is perforated, however, or if there is
a perforation into the perilymph system, vertigo will occur, especially when
water enters the ear.
The inner ear is the site of two important causes of vertigo, acute
labyrinthitis and Ménière disease. Acute labyrinthitis is more often
toxic than infectious (viral) in nature. Drugs such as streptomycin and
gentomycin are common causes, but aspirin and quinidine should be considered
with a host of other drugs. This can be determined by a good history without
looking up the long list of drugs. Perhaps more common and more important
from a legal standpoint is traumatic labyrinthitis from head injuries. The
cause of Ménière disease is not known, but swelling of the
endolymphatic ducts is probably the major pathophysiologic mechanism. If the
internal auditory artery is obstructed by spasm (as occurs in
migraine), basilar artery insufficiency, or thrombosis, vertigo will result.
Rarely, an aneurysm of this artery or the basilar artery at its branching
may compress or hemorrhage into the vestibular nerve and cause vertigo.
Additional neurologic causes of vertigo are acoustic neuromas and other
brainstem tumors, petrositis, and vestibular neuronitis, which may involve
the vestibular nerve or nucleus. Finally, central vertigo may result from
multiple sclerosis, concussion, epilepsy, and cerebral tumors.
Approach to the Diagnosis
The first step is to determine if the patient has true vertigo. True
vertigo is the experience of subjective or objective rotation with respect
to the environment. In other words, either the patient or his or her
environment is turning. One other form of true vertigo is lateral pulsion.
This is the feeling that one is moving sideways when that is not the case.
The patient who does not experience true vertigo should have a syncope
workup . Narrowing the
differential diagnosis of true vertigo depends on the presence or absence of
other symptoms and signs. If there are other cranial nerve or long tract
signs on neurologic examination, the patient may have a space-occupying
lesion of the brain or brainstem or a hemorrhage, thrombosis, or embolism in
the vertebral–basilar artery distribution. A neurology consult should be
obtained.
If there is true vertigo, tinnitis, and deafness, one would consider inner
ear pathology such as Ménière disease, syphilis, petrositis,
mastoiditis, and acoustic neuroma. If there is vertigo without tinnitus,
deafness, or focal neurologic signs, the clinician should suspect acute
labyrinthitis, vestibular neuronitis, benign positional vertigo, and drug
toxicity. If there are rapid respirations during the attack of vertigo, one
would consider hyperventilation syndrome. If there are significant findings
on otoscopic examination, a diagnosis of otitis media, cholesteatoma, or
mastoiditis should be considered.
The workup will depend on whether the patient has objective findings on
otoscopic or neurologic examination. If local pathology is suspected,
perhaps a tympanogram, x-ray of the mastoids and petrous bones, audiogram,
or referral to an otolaryngologist are required. If there are neurologic
findings, perhaps a CT scan or MRI of the brain and auditory canal is
indicated along with a referral to a neurologist. It is wise to have a
specialist on board before ordering an expensive workup.
Other Useful Tests
-
Thyroid profile (vertigo from thyroid disease)
- Electronystagmogram (Ménière disease)
- Brainstem evoked potentials (multiple sclerosis)
- Caloric testing (Ménière disease)
- Drug screen (drug abuse)
- Hallpike maneuvers (benign positional vertigo)
- VDRL or Fluorescent Treponemal Antibody Absorption (FTA-ABS) test (neurosyphilis)
Pictures
Book Source Details
- Book Title: Differential Diagnosis in Primary Care
- Author(s): R. Douglas Collins MD, FACP
- Year of Publication: 2007
- Copyright Details: Differential Diagnosis in Primary Care, Copyright © 2007 Lippincott Williams & Wilkins.
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Copyright notice for book excerpts: Copyright © 2008 Lippincott Williams & Wilkins. All rights reserved.
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