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Diagnosis of blastomycosis requires:
❑culture of B. dermatitidis from skin lesions, pus, sputum, or pulmonary secretions
❑microscopic examination of tissue specimens from the skin or the lungs or of bronchial washings, sputum, or pus, as the physician finds appropriate
❑immunodiffusion testing, which detects antibodies for the A and B antigen of blastomycosis.
In addition, suspected pulmonary blastomycosis requires a chest X-ray, which may show pulmonary infiltrates. Other abnormal laboratory findings include increased white blood cell count and erythrocyte sedimentation rate, slightly increased serum globulin levels, mild normochromic anemia and, with bone lesions, increased alkaline phosphatase.
Source: Professional Guide to Diseases (Eighth Edition), 2005
Various tests may be ordered to diagnose blastomycosis, including:
❑ culture of B. dermatitidis from skin lesions, pus, sputum, or pulmonary secretions
❑ biopsy of tissue from the skin or lungs or of bronchial washings, sputum or pus as appropriate
❑ immunodiffusion testing. This specific study detects antibodies for the A and B antigen of blastomycosis.
In addition, suspected pulmonary blastomycosis requires a chest X-ray, which may show pulmonary infiltrates. Other abnormal laboratory findings include an increased white blood cell count and erythrocyte sedimentation rate, slightly increased serum globulin levels, mild normochromic anemia and, with bone lesions, an increased alkaline phosphatase level.
Source: Handbook of Diseases, 2003
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