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Diseases » Chickenpox » Prevalence
 

Prevalence and Incidence of Chickenpox

Chickenpox Prevalence: Book Excerpts

Incidence (annual) of Chickenpox:

120,624 annually (1995); 46,016 annual cases notified in USA 1999 (MMWR 1999); 199.14 per 100,000 in Canada 20001 ... see also overview of Chickenpox.

Incidence Rate:

approx 1 in 2,254 or 0.04% or 120,624 people in USA [Source statistic for calcuation: "120,624 annually (1995); 46,016 annual cases notified in USA 1999 (MMWR 1999); 199.14 per 100,000 in Canada 20001" -- see also general information about data sources]

Incidence extrapolations for USA for Chickenpox:

120,624 per year, 10,052 per month, 2,319 per week, 330 per day, 13 per hour, 0 per minute, 0 per second. [Source statistic for calculation: "120,624 annually (1995); 46,016 annual cases notified in USA 1999 (MMWR 1999); 199.14 per 100,000 in Canada 20001" -- see also general information about data sources]

Incidence of types of Chickenpox:

For details see incidence of types of Chickenpox analysis; summary of available incidence by type data:

Prevalance of Chickenpox:

Almost everyone gets chickenpox by adulthood (more than 95% of Americans). Chickenpox is highly contagious. CDC estimates that 4 million cases occur each year. (Source: excerpt from Facts About Chickenpox (Varicella): CDC-OC)

More Statistics about Chickenpox:

  • Deaths and related statistics
  • Hospitalization statistics
  • All statistics for Chickenpox

    Prevalence/Incidence of Chickenpox: Online Medical Books

    16 MEDICAL BOOKS ONLINE! Review excerpts from medical books online, free, without registration, for more information about the prevalence and/or incidence of Chickenpox.

    Herpes zoster: Causes and incidence
    (Professional Guide to Diseases (Eighth Edition))

    Herpes zoster results from reactivation of varicella virus that has lain dormant in the cerebral ganglia (extramedullary ganglia of the cranial nerves) or the ganglia of posterior nerve roots since a previous episode of chickenpox. Exactly how or why this reactivation occurs isn’t clear. Some believe that the virus multiplies as it's reactivated and that antibodies remaining from the initial infection neutralize it. However, if effective antibodies aren't present, the virus continues to multiply in the ganglia, destroy the host neuron, and spread down the sensory nerves to the skin.

    Herpes zoster occurs primarily in adults, especially those older than age 50. It seldom recurs. It's also seen in patients with human immunodeficiency virus and other immunodeficiency disorders.

    » READ BOOK EXCERPT ONLINE »

    Source: Professional Guide to Diseases (Eighth Edition), 2005

    Varicella: Causes and incidence
    (Professional Guide to Diseases (Eighth Edition))

    Chickenpox can occur at any age, but it's most common in children ages 2 to 8. Congenital varicella may affect infants whose mothers had acute infections in their first or early second trimester. Neonatal infection is rare, probably because of transient maternal immunity. However, neonates born to mothers who develop varicella 5 days before delivery or up to 2 days after delivery are at risk for developing severe generalized varicella. Second attacks are also rare. This infection is transmitted by direct contact (primarily with respiratory secretions; less commonly, with skin lesions) and indirect contact (airborne). The incubation period usually lasts 14 to 17 days but can be as short as 10 days and as long as 20 days. (See Incubation and duration of common rash-producing infections, page 232.) Chickenpox is probably communicable from 1 day before lesions erupt to 6 days after vesicles form (it's most contagious in the early stages of eruption of skin lesions).

    Chickenpox occurs worldwide and is endemic in large cities. Outbreaks occur sporadically, usually in areas with large groups of susceptible children. It affects all races and both sexes equally. Seasonal distribution varies; in temperate areas, incidence is higher during late autumn, winter, and spring.

    Most children recover completely. Potentially fatal complications may affect children on corticosteroids, antimetabolites, or other immunosuppressants and those with leukemia, other neoplasms, or immunodeficiency disorders. Congenital and adult varicella may also have severe effects.

    » READ BOOK EXCERPT ONLINE »

    Source: Professional Guide to Diseases (Eighth Edition), 2005

    Chickenpox (Varicella, Herpes Zoster): Chickenpox - epidemiology
    (The 5-Minute Pediatric Consult)

    • Person-to-person transmission occurs by direct contact with varicella or zoster and respiratory secretions.
    • Varicella is most common during late winter and early spring, but seasonality is now less pronounced.
    • The introduction of an index case of varicella into a home results in transmission of the virus to susceptible persons and secondary cases of disease in 87–98% of susceptible persons:
      • Secondary cases in this situation usually have more severe disease.
      • Most reported cases occur between the ages of 5 and 9 years, although in areas of the US, where many 1–4-year-olds are in daycare, this age group predominates with an increase in complications. Since 2002, regions where vaccine coverage is >80% have experienced increasing numbers of adolescents and adults with varicella secondary to having not been vaccinated and remaining susceptible.
    • Immunity from natural disease is usually lifelong, but symptomatic reinfections do occur; more common are asymptomatic reinfections, with a 4-fold boost in antibody level. The 2nd dose of vaccine boosts titers 12-fold to levels seen after natural disease.
    • Immunocompromised individuals with either primary varicella or zoster are at risk for severe disease.
    • Disease is also more severe in infants >3 months, adolescents, adults, persons on oral and/or IV steroids or long-term aspirin therapy, or persons with pulmonary disorders including asthma.
    • Congenital varicella syndrome risk is about 2% and is greatest from the 12th to the 20th week of gestation.
    • Incubation 10–21 days after contact; cases most contagious 2 days before the rash appears and until 5 days after lesions stop cropping (longer in immunocompromised patients)
    • In varicella-active surveillance sites, breakthrough varicella or reinfection with varicella now represents 62% of all reported varicella cases. These rashes are atypical of varicella, are of shorter duration, usually have fewer lesions, are usually itchy, come in crops, and scab. Individuals with >50 lesions have been shown to transmit disease; however, it is less contagious (30%) than natural VZV (87%). When the diagnosis is in doubt; it may be verified by either polymerase chain reaction (PCR) of the lesion and/or acute and convalescent serum IgG showing a rise in titer. Only wild-type varicella has been identified from these confirmed cases of reinfection (breakthrough) VZV. Using these diagnostic tests, the Centers for Disease Control and Prevention (CDC) Varicella Active Surveillance Project in Philadelphia has demonstrated that 50% of what physicians thought might be a VZV reinfection is not.

    » READ BOOK EXCERPT ONLINE »

    Source: The 5-Minute Pediatric Consult, 2008

    About prevalence and incidence statistics:

    The term 'prevalence' of Chickenpox usually refers to the estimated population of people who are managing Chickenpox at any given time. The term 'incidence' of Chickenpox refers to the annual diagnosis rate, or the number of new cases of Chickenpox diagnosed each year. Hence, these two statistics types can differ: a short-lived disease like flu can have high annual incidence but low prevalence, but a life-long disease like diabetes has a low annual incidence but high prevalence. For more information see about prevalence and incidence statistics.

    Footnotes:
    1. Notifiable Diseases Online, PPHB, Canada, 2000


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