Diagnosis of Cholestasis
Cholestasis Diagnosis: Book Excerpts
Diagnostic Tests for Cholestasis: Online Medical Books
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Introduction: Hepatobiliary Disorders:
Comprehensive history essential
(Professional Guide to Diseases (Eighth Edition))
Ask if the patient has ever had jaundice, anemia, or a splenectomy. Ask about occupational or other exposure him to toxins (carbon tetrachloride, beryllium, or vinyl chloride), which may predispose him to hepatic disease.Consider recent travel or contact with persons who have traveled to areas where hepatic disease is endemic.
Make sure to ask about alcohol consumption, a significant factor in suspected hepatic disease. Remember, an alcoholic may deliberately underestimate his alcohol intake, so interview the patient’s family as well. Ask about recent contact with a jaundiced person and about any recent blood or plasma transfusions, blood tests, tattoos, or dental work. Find out if the patient takes any drugs that may cause liver damage, such as sedatives, tranquilizers, analgesics, and diuretics that cause potassium loss. Ask if the onset of symptoms was abrupt or insidious or if it followed abdominal injury that could have damaged the liver. Ask if the patient bruises or bleeds easily. Check the color of stools and urine, and ask about any change in bowel habits. Also ask if the patient’s weight has fluctuated recently.
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Source: Professional Guide to Diseases (Eighth Edition), 2005
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