Cure Research for High Cholesterol

Curable Types of High Cholesterol

Possibly curable or rare types of High Cholesterol include:

• Nephrotic syndrome induced hypercholesterolemia
• Alcohol induced hypercholesterolemia
• Steroid induced hypercholesterolemia
• Anorexia nervosa induced hypercholesterolemia
• Hypothyroidism induced hypercholesterolemia
• more curable types...»

Rare Types of High Cholesterol:

Some rare types of High Cholesterol include:

• Acute pancreatitis induced hypercholesterolemia
• Glycogen storage disease induced hypercholesterolemia
• Anorexia nervosa induced hypercholesterolemia
• more rare types...»

Treatments for High Cholesterol

Treatments to consider for High Cholesterol may include:

• Cholesterol medications
  • Hormone Replacement Therapy - for menopausal women.
  • Statins
    • Lovastatin
    • Simvastatin
• more treatments...»

Medical Research Breakthroughs and High Cholesterol

Dark chocolate and Cholesterol: Eating two CocoaVia dark chocolate bars a day has not only lowered cholesterol, it has also had the unexpected effect of also lowering systolic blood pressure, as found by researchers at University of Illinois. The drop in cholesterol numbers (total cholesterol by 2 percent and LDL or "bad" cholesterol by 5.3 percent) to the plant sterols that have been added to the bar and the drop in blood pressure to the flavanols found in dark chocolate. Eating Plan for Healthy Americans" (formerly the Step 1 diet) two weeks before the study started; then they were divided into two matched groups. Two types of CocoaVia bars were then introduced one with plant sterols and one without. While remaining on the AHA diet, participants ate one CocoaVia formulation twice daily for four weeks, and then switched to the other bar for an additional four weeks. Blood cholesterol levels, blood pressure, body weight, and other cardiovascular measures were tracked throughout the eight-week study. After starting the CocoaVia bars, the research team saw a marked differential effect on blood cholesterol, with the sterol-containing products doing better than those without sterols.

Medical research for High Cholesterol: medical news summaries:

The following medical news items are relevant to medical research for High Cholesterol:

• Alcohol consumption may have a protective effect against metabolic syndrome
• Alternative view of health
• Assessment of rhabdomyolysis risk of various cholesterol drugs
• Atkins diet at its best when used in the short term
• Baycol should have been pulled from the market sooner
• Blood pressure and cholesterol drugs may greatly benefit some dementia sufferers
• Blueberries found to be effective in reducing cholesterol
• Breast cancer drug Femara superior to Tamoxifen
• Cancer risk increased by high blood iron and cholesterol
• Children increasingly face adult diseases
• Cholesterol lowering medication protective against Alzheimer’s disease
• Cinnamon extract benefits diabetics
• Combination therapy causes significant reduction in risk of heart attack
• Complications of pregnancy link to future stroke risk
• COPD improved with cholesterol lowering agent
• CRP may be linked to risk of heart disease
• Dementia more prevalent in black Americans
• Dementia risk factors determined
• Diabetics need to be more aware of benefits of aspirin
• Diet low in cholesterol prescribed for pregnancy
• Early cessation of steroid following liver transplant increases rate of rejection
• Experimental weight-loss drug shows multitude of health benefits
• Fatty liver disease becoming popular
• Fiber may assist statin action in reducing cholesterol
• High cholesterol and blood pressure may be linked to dementia
• High cholesterol in women needs to be given more attention
• High cholesterol reduced by exercising and consuming plant sterols
• Higher cholesterol found with decaffeinated coffee drinkers
• How much is really known about the safety of statins
• Inherited high cholesterol may be subdued by omega-3 fat
• Long term effects of obesity surgery examined
• Long term medications need to be carefully assessed to determine health benefits
• Long-term effects anti-retroviral treatment for AIDS being studied
• MBL protein level linked to heart attack risk in diabetics
• Natural cholesterol lowering drug has now side effects
• New blood pressure drugs overwhelmingly more effective than older drugs
• New research suggests that low birth weight is not linked to increased risk of high cholesterol in adults
• Niacin increases HDL levels thus reducing heart disease risk
• Obesity is associated with an increased risk of many conditions
• Policosanol more effective and safer than statin drugs
• Proposed over the counter cholesterol drug still under doubt
• Researchers examine relationship between prostate cancer and high cholesterol
• Statin drugs carry low risk of muscle damage leading to kidney failure
• Statins may benefit people at low risk of heart disease
• Statins use with cholesterol and cancer
• Study shows oral contraceptives taken before menopause may reduce risk of cancer and heart disease
• Weight loss drug, orlistat, proves itself in trials
• More news »

Clinical Trials for High Cholesterol

Some of the clinical trials for High Cholesterol include:

• Phase I Study of Ex Vivo Liver-Directed Gene Therapy for Familial Hypercholesterolemia - This study has been completed (Current: 23 Nov 2006)
• PLUTO: Pediatric Lipid-redUction Trial of rOsuvastatin - This study is currently recruiting patients (Current: 23 Nov 2006) - Rosuvastatin
• Effect of TAK-475 or Placebo co-Administered With Current Lipid-Lowering Treatment on Blood Cholesterol Levels in Subjects With Homozygous Familial Hypercholesterolemia. - This study is currently recruiting patients (Current: 23 Nov 2006) - TAK-475
• Efficacy and Safety of Fluvastatin in Children With Heterozygous Familial Hypercholesterolemia - This study has been completed (Current: 23 Nov 2006) - Fluvastatin
• Dose-Escalating Safety Study of ISIS 301012 in Homozygous Familial Hypercholesterolemia Subjects on Lipid Lowering Therapy - This study is currently recruiting patients (Current: 23 Nov 2006) - ISIS 301012
• more trials...»

Evidence Based Medicine Research for High Cholesterol

Medical research papers related to High Cholesterol include:

• I have a patient with no previous CHD but has high cholesterol and is intolerant of statins what is recommended?
• LIPOchip DNA microarray for the detection of familial hypercholesterolaemia
• ACAT inhibition and progression of carotid atherosclerosis in patients with familial hypercholesterolemia: the CAPTIVATE randomized trial.
• Should patients with high cholesterol be advised to reduce the amount of eggs and prawns they eat?
• Identification and management of familial hypercholesterolaemia
• Ezetimibe for the treatment of hypercholesterolaemia: a systematic review and economic evaluation
• Ezetimibe for the treatment of hypercholesterolaemia: a systematic review and economic evaluation
• Colesevelam hydrochloride (Cholestagel) - primary hypercholesterolaemia
• AVE5530 Treatment of hypercholesterolaemia
• Ezetimibe (Ezetrol) Hypercholesterolaemia in adolescents
• Ezetimibe in hypercholesterolaemia: NICE guidance Safety concerns with rimonabant Paediatric cough and cold medicines - no help, some harm
• The cost-effectiveness of the treatment of high risk women with osteoporosis, hypertension and hyperlipidaemia in Sweden
• Efficacy of statins in familial hypercholesterolaemia: a long term cohort study.
• For a 14 year old girl who has hereditary hyperlipidaemia using a statin for treatment, is the desogestrel-only pill a suitable contraceptive option?
• Ezetimibe for the treatment of adult patients with hypercholesterolemia
• Middle aged lady with eGFR 40 and mixed hyperlipidaemia. Cholesterol well controlled but triglycerides 3.2. What are the best triglyceride lowering agents and is it safe in the case to co-prescribe with a statin?
• Simvastatin with or without ezetimibe in familial hypercholesterolemia.
• Efficacy and safety of coadministration of ezetimibe and simvastatin in adolescents with heterozygous familial hypercholesterolemia
• Statins are not associated with a reduced risk of pancreatic cancer at the population level, when taken at low doses for managing hypercholesterolemia: evidence from a meta-analysis of 12 studies
• Comparison of genetic versus clinical diagnosis in familial hypercholesterolemia
• Is there evidence to support use of fenofibrate in a type 2 diabetic who is statin intolerant with hypercholesterolaemia?
• We are following the guidelines re lowering cholesterol where there is a CVD risk of 20%. We have a number of patients who have high cholesterols e.g. TC>7 LDL>4 but no other risk factors, so the CVD is <15%. Should we be treating the high cholesterol?
• In a patient with raised total cholesterol, due to a high level of ?good? cholesterol, should we advise that they have high cholesterol?
• Diagnosis and treatment of childhood hypercholesterolaemia.
• Ezetimibe for the treatment of primary (heterozygous-familial and non-familial) hypercholesterolaemia
• Treatment of hyperlipidaemia: aims and selection.
• Genetic screening for familial hypercholesterolaemia
• Child-parent screening for familial hypercholesterolaemia: screening strategy based on a meta-analysis.
• In a 50 year old lady with HOCM (hypertrophic obstructive cardiomyopathy) and a history of rheumatic fever would it be appropriate to treat raised cholesterol levels with a statin.
• If a patient has a raised cholesterol, but the TC:HDL ratio is within range, do they need treatment with a statin or just dietary advice?

Click here to find more evidence-based articles on the TRIP Database

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