Treatments for Congenital adrenal hyperplasia
Treatments for Congenital adrenal hyperplasia
The list of treatments mentioned in various sources
for Congenital adrenal hyperplasia
includes the following list.
Always seek professional medical advice about any treatment
or change in treatment plans.
Congenital adrenal hyperplasia: Is the Diagnosis Correct?
The first step in getting correct treatment is
to get a correct diagnosis.
Differential diagnosis list for Congenital adrenal hyperplasia may include:
Congenital adrenal hyperplasia: Marketplace Products, Discounts & Offers
Products, offers and promotion categories available for Congenital adrenal hyperplasia:
Congenital adrenal hyperplasia: Research Doctors & Specialists
Research all specialists including ratings, affiliations, and sanctions.
Unlabeled Drugs and Medications to treat Congenital adrenal hyperplasia:
Unlabelled alternative drug treatments for Congenital adrenal hyperplasia include:
- Flutamide - used as part of a combination treatment
- Apo-Flutamide - used as part of a combination treatment
- Euflex - used as part of a combination treatment
- Eulexin - used as part of a combination treatment
- Flutamex - used as part of a combination treatment
Hospital statistics for Congenital adrenal hyperplasia:
These medical statistics relate to hospitals, hospitalization and Congenital adrenal hyperplasia:
- 0.005% (612) of hospital consultant episodes were for adrenogenital disorders in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
- 97% of hospital consultant episodes for adrenogenital disorders required hospital admission in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
- 44% of hospital consultant episodes for adrenogenital disorders were for men in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
- 56% of hospital consultant episodes for adrenogenital disorders were for women in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
- more hospital information...»
Hospitals & Medical Clinics: Congenital adrenal hyperplasia
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More general information, not necessarily in relation to Congenital adrenal hyperplasia,
on hospital and medical facility performance and surgical care quality:
Discussion of treatments for Congenital adrenal hyperplasia:
CAH cannot be cured, but it can be treated by replacing the missing hormones. In particular, it is essential to give more cortisol in times of stress.
(Source: Genes and Disease by the National Center for Biotechnology)
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Book Excerpts: Treatment of Congenital adrenal hyperplasia
Treatments of Congenital adrenal hyperplasia: Online Medical Books
16 MEDICAL BOOKS ONLINE!
Review excerpts from medical books online, free, without registration,
for more information about the treatments of Congenital adrenal hyperplasia.
Hearing Loss – Congenital:
Treatment
(In A Page: Pediatric Signs and Symptoms)
-
Identify children with hearing loss early
-
Treat medically treatable cause, if any
–Syphilis (steroids and penicillin), Lyme disease, toxoplasmosis, hypercholesterolemia
-
Intravenous gancyclovir for congenital CMV
-
Habilitate by age 6 months if possible
–Amplification
–Bone-anchored hearing aids
–Tympanostomy tube placement
–Middle ear reconstruction
–Perilymphatic fistula closure
–Cochlear implant (after age 12 months)
-
Periodic follow-up necessary
–Ensure auditory habilitation is working
–Check for hearing loss progression
>
» READ BOOK EXCERPT ONLINE »
Source: In A Page: Pediatric Signs and Symptoms, 2007
Adrenal crisis:
Treatment (Tx)
(Professional Guide to Diseases (Eighth Edition))
Replacement of corticosteroids, I.V. fluids, potassium, insulin
» READ BOOK EXCERPT ONLINE »
Source: Professional Guide to Diseases (Eighth Edition), 2005
Adrenal hypofunction:
Treatment
(Professional Guide to Diseases (Eighth Edition))
For all patients with primary or secondary adrenal hypofunction, corticosteroid replacement, usually with cortisone or hydrocortisone (both of which also have a mineralocorticoid effect), is the primary treatment and must continue throughout life. Adrenal hypofunction may also necessitate treatment with I.V. desoxycorticosterone, a pure mineralocorticoid, or oral fludrocortisone, a synthetic mineralocorticoid; both prevent dangerous dehydration and hypotension.
Adrenal crisis requires prompt I.V. bolus administration of hydrocortisone. Later, doses are given I.M. or are diluted with dextrose in saline solution and given I.V. until the patient’s condition stabilizes.
With proper treatment, adrenal crisis usually subsides quickly; the patient’s blood pressure should stabilize, and water and sodium levels should return to normal. After the crisis, maintenance doses of hydrocortisone preserve physiologic stability.
» READ BOOK EXCERPT ONLINE »
Source: Professional Guide to Diseases (Eighth Edition), 2005
Adrenogenital syndrome:
Treatment
(Professional Guide to Diseases (Eighth Edition))
Simple virilizing CAH requires correction of the cortisol deficiency and inhibition of excessive pituitary corticotropin production by daily administration of cortisol. Treatment returns androgen production to normal levels. Measurement of urinary 17-KS levels determines the initial dose of cortisone or hydrocortisone; this dose is usually large and is given I.M. Later dosage is modified according to decreasing urinary 17-KS levels. Infants must continue to receive cortisone or hydrocortisone I.M. until age 18 months; after that, they may take it orally.
PEDIATRIC TIP The infant with salt-losing CAH in adrenal crisis requires immediate I.V. sodium chloride and glucose infusion to maintain fluid and electrolyte balance and to stabilize vital signs. If saline and glucose infusion doesn’t control symptoms while the diagnosis is being established, desoxycorticosterone I.M. and hydrocortisone I.V. are necessary. Later, maintenance includes mineralocorticoid (desoxycorticosterone, fludrocortisone, or both) and glucocorticoid (cortisone or hydrocortisone) replacement.
Sex chromatin and karyotype studies determine the genetic sex of patients with ambiguous external genitalia. Females with masculine external genitalia require reconstructive surgery, such as correction of the labial fusion and of the urogenital sinus. Surgery is usually scheduled between ages 1 and 3, after the effect of cortisone therapy has been assessed.
» READ BOOK EXCERPT ONLINE »
Source: Professional Guide to Diseases (Eighth Edition), 2005
Adenoid hyperplasia:
Treatment
(Professional Guide to Diseases (Eighth Edition))
Adenoidectomy is the treatment of choice for adenoid hyperplasia and is commonly recommended for the patient with prolonged mouth breathing, nasal speech, adenoid facies, recurrent otitis media, constant nasopharyngitis, and nocturnal respiratory distress. This procedure usually eliminates recurrent nasal infections and ear complications and reverses any secondary hearing loss.
» READ BOOK EXCERPT ONLINE »
Source: Professional Guide to Diseases (Eighth Edition), 2005
Adrenal hypofunction:
Treatment
(Handbook of Diseases)
For all patients with primary or secondary adrenal hypofunction, lifelong corticosteroid replacement, usually with cortisone or hydrocortisone (both of which also have a mineralocorticoid effect) is the primary treatment.
For patients with Addison’s disease, treatment with oral fludrocortisone, a synthetic mineralocorticoid, is necessary to prevent dangerous dehydration, hypotension, and electrolyte disturbances with hyponatremia and hyperkalemia. (See Avoiding adrenal crisis.)
For those with adrenal crisis, prompt I.V. bolus administration of 100 mg of hydrocortisone is key. Later, 50- to 100-mg doses are given I.M. or are diluted with dextrose in saline solution and given I.V. until the patient’s condition stabilizes; up to 300 mg/day of hydrocortisone and 3 to 5 L of I.V. saline solution are required during the acute stage of adrenal crisis.
With proper treatment, adrenal crisis usually subsides quickly; the patient’s blood pressure stabilizes, and water and sodium levels return to normal. After the crisis, maintenance doses of hydrocortisone preserve physiologic stability.
» READ BOOK EXCERPT ONLINE »
Source: Handbook of Diseases, 2003
Congenital Infections:
Management
(Pediatric Infectious Disease)
Patients with congenital CMV infection are at risk for a variety of
disabilities, including developmental delay and hearing loss. Symptomatic
children are considered to have the highest risk for long-term abnormalities,
although recent longitudinal studies have found predicting disability
difficult. It is known that the major disability in asymptomatic congenital CMV
infection is sensorineural hearing loss. This hearing loss may be progressive
in affected infants. After a diagnosis of congenital CMV is made, routine
assessments should be instituted. It has been recommended that a careful
ophthalmology exam be performed at 12 months, 3 years, and at entrance to
preschool. Audiology examinations should be done every 3 months until 3 years
of age and then annually.
No definitive protocols exist for the treatment of congenital CMV infection.
Clinical trials are in progress; a recent randomized clinical trial comparing
outcomes in symptomatic infants given the antiviral agent ganciclovir with
those in patients receiving no treatment suggested that there may be a benefit
from treatment, the greatest benefit in treated children being a reduction in
hearing loss. In early protocols of treatment of CMV, symptomatic infants were
administered intravenous ganciclovir for 6 weeks; later studies extended
treatment of affected infants with intravenous and then oral ganciclovir for up
to 1 year. Currently, it is not recommended that asymptomatic infants found to
be congenitally infected receive ganciclovir. These children should be followed
carefully for the development of sensorineural hearing loss. Neonates with
life-threatening symptomatic disease, including intractable thrombocytopenia,
pneumonia, or hepatic failure, are candidates for antiviral therapy. It is my
experience and the experience of investigators nationally that therapy can be
very beneficial in these cases.
Complications of ganciclovir include difficulties in maintaining intravenous
access and neutropenia. There will likely be continued efforts to identify
precisely and treat those infants likely to have long-term sequelae from
congenital CMV infection and those most likely to benefit from therapy.
» READ BOOK EXCERPT ONLINE »
Source: Pediatric Infectious Disease, 2004
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