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Diseases » Congenital glaucoma » Treatments
 

Treatments for Congenital glaucoma

Treatments for Congenital glaucoma

The list of treatments mentioned in various sources for Congenital glaucoma includes the following list. Always seek professional medical advice about any treatment or change in treatment plans.

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Book Excerpts: Treatment of Congenital glaucoma

Treatments of Congenital glaucoma: Online Medical Books

16 MEDICAL BOOKS ONLINE! Review excerpts from medical books online, free, without registration, for more information about the treatments of Congenital glaucoma.

Glaucoma: Treatment
(Professional Guide to Diseases (Eighth Edition))

For chronic open-angle glaucoma, treatment initially decreases IOP through the use of an alpha antagonist, brimonidine tartrate (Alphagan), and then beta blockers, such as timolol (contraindicated for asthmatics or patients with bradycardia) or betaxolol (Betoptic) to reduce aqueous humor production. A topical anhydrase inhibitor is used in preference to a systemic anhydrase inhibitor such as acetazolamide. A tubo-plast or tube shunt or valve may also be used. Miotic eyedrops such as pilocarpine facilitate the outflow of aqueous humor.

Patients who are unresponsive to drug therapy may be candidates for argon laser trabeculoplasty (ALT) or a surgical filtering procedure called trabeculectomy, which creates an opening for aqueous outflow. In ALT, an argon laser beam is focused on the trabecular meshwork of an open angle. This produces a thermal burn that changes the surface of the meshwork and increases the outflow of aqueous humor. In trabeculectomy, a flap of sclera is dissected free to expose the trabecular meshwork. Then this discrete tissue block is removed and a peripheral iridectomy is performed. This produces an opening for aqueous outflow under the conjunctiva, creating a filtering bleb. In chronic refractory glaucoma, a tubo-plast or tube shunt or valve is used to keep IOP within normal limits.

Acute angle-closure glaucoma is an ocular emergency requiring immediate treatment to lower the high IOP. Preoperative drug therapy lowers IOP with I.V. acetazolamide, pilocarpine (constricts the pupil, forcing the iris away from the trabeculae, allowing fluid to escape), timolol, and a topical steroid to quiet the inflammatory response, along with I.V. mannitol (20%) or oral glycerin (50%) to force fluid from the eye by making the blood hypertonic. Latanoprost is a topical medication that helps drain the aqueous outflow from the eye and lower the IOP. Oral medication or topical drops may be prescribed separately or in combination. Severe pain may necessitate administration of opioid analgesics. If pressure doesn’t decrease with drug therapy, laser iridotomy or surgical peripheral iridectomy must be performed promptly to save the patient’s vision. Iridectomy relieves pressure by excising part of the iris to reestablish aqueous humor outflow. A prophylactic iridectomy is performed a few days later on the other eye to prevent an acute episode of glaucoma in the normal eye.

» READ BOOK EXCERPT ONLINE »

Source: Professional Guide to Diseases (Eighth Edition), 2005

Glaucoma: Treatment
(Handbook of Diseases)

Drug therapy is the treatment of choice for chronic open-angle glaucoma. If this fails, argon laser trabeculoplasty or trabeculectomy is performed. Acute angle-closure glaucoma is treated with drugs, laser iridotomy, or surgical peripheral iridectomy.

Drug therapy for chronic open-angle glaucoma

For chronic open-angle glaucoma, treatment initially decreases aqueous humor production through beta-adrenergic blockers, such as timolol (contraindicated for patients with asthma or those with bradycardia) and betaxolol (a beta1-receptor antagonist); alpha agonists, such as brimonidine, to lower IOP; and topical carbonic anhydrase inhibitors such as dorzolamide.

Drug treatment also includes miotic eyedrops, such as pilocarpine, to facilitate the outflow of aqueous humor. Patients who are unresponsive to drug therapy may be candidates for iridectomy, a surgical filtering procedure that creates an opening for aqueous outflow.

Clinical tip  The end stage of glaucoma may require a tube shunt or valve to keep IOP down.

Argon laser trabeculoplasty

In argon laser trabeculoplasty, an argon laser beam is focused on the trabecular meshwork of an open angle. This produces a thermal burn that changes the surface of the meshwork and increases the outflow of aqueous humor.

Trabeculectomy

In trabeculectomy, a flap of sclera is dissected free to expose the trabecular meshwork. This discrete tissue block is then removed, and a peripheral iridectomy is performed. This procedure produces an opening for aqueous outflow under the conjunctiva, creating a filtering bleb.

Treatment for ACUTE angle-closure glaucoma

Acute angle-closure glaucoma is an ocular emergency that requires immediate treatment to lower the high IOP. If the pressure doesn’t decrease with drug therapy, laser iridotomy or surgical peripheral iridectomy must be performed promptly to save the patient’s vision.

Iridectomy relieves pressure by excising part of the iris to reestablish aqueous humor outflow. A prophylactic iridectomy is performed a few days later on the patient’s other eye to prevent an acute episode of glaucoma in that eye.

Preoperative drug therapy lowers IOP with I.V. mannitol and steroid drops to quell the inflammation. Acetazolamide is used as well as pilocarpine (which constricts the pupil, forcing the iris away from the trabeculae and allowing fluid to escape) and I.V. mannitol (20%) or oral glycerin (50%) to force fluid from the eye by making the blood hypertonic. Timolol is used to decrease IOP. Severe pain may necessitate narcotic analgesics.

» READ BOOK EXCERPT ONLINE »

Source: Handbook of Diseases, 2003



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