Causes of Coronary heart disease

List of causes of Coronary heart disease

Following is a list of causes or underlying conditions (see also Misdiagnosis of underlying causes of Coronary heart disease) that could possibly cause Coronary heart disease includes:

• Atheroma
• Atherosclerosis

Longer list of causes of Heart symptoms: see full list of causes for Heart symptoms

Coronary heart disease Causes: Book Excerpts

• Causes and incidence - Coronary artery disease
• Causes - Coronary artery disease
• Anomalous Coronary Artery - pathophysiology - Anomalous Coronary Artery

Coronary heart disease as a complication of other conditions:

Other conditions that might have Coronary heart disease as a complication may, potentially, be an underlying cause of Coronary heart disease. Our database lists the following as having Coronary heart disease as a complication of that condition:

• Conn's adenoma
• Conn's syndrome
• Conn-Louis Carcinoma
• Defective apolipoprotein B-100
• Familial Apolipoprotein A-I and C-III Deficiency
• Familial Apolipoprotein A-I, C-III, A-IV Deficiency
• Heterozygous Familial Hypercholesterolemia
• High Cholesterol
• Homozygous Familial Hypercholesterolemia
• Hypercholesterolemia due to arg3500 mutation of Apo B-100
• Hypercholesterolemia due to LDL receptor deficiency
• Hyperlipoproteinemia
• Metabolic Syndrome
• Physical inactivity
• Type I Hyperlipoproteinemia
• Type Ia Hyperlipoproteinemia
• Type Ib Hyperlipoproteinemia
• Type Ic Hyperlipoproteinemia
• Type II Hyperlipoproteinemia
• Type IIa Hyperlipoproteinemia
• Type IIb Hyperlipoproteinemia
• Type III Hyperlipoproteinemia
• Type IV Hyperlipoproteinemia
• Type V Hyperlipoproteinemia

Coronary heart disease as a symptom:

Conditions listing Coronary heart disease as a symptom may also be potential underlying causes of Coronary heart disease. Our database lists the following as having Coronary heart disease as a symptom of that condition:

• Acromegaly
• Coronary artery disease, autosomal dominant 1
• Coronary artery disease, autosomal dominant 2
• Coronary heart disease, susceptibility to, 1
• Coronary heart disease, susceptibility to, 2
• Coronary heart disease, susceptibility to, 3
• Coronary heart disease, susceptibility to, 4
• Coronary heart disease, susceptibility to, 5
• Coronary heart disease, susceptibility to, 6
• Coronary heart disease, susceptibility to, 7
• Coronary heart disease, susceptibility to, 8
• Coronary heart disease, susceptibility to, 9
• Fabry's Disease
• Heterozygous Familial Hypercholesterolemia
• Homozygous Familial Hypercholesterolemia
• Hypercholesterolemia, autosomal dominant
• Niemann-Pick disease

What causes Coronary heart disease?

Causes: Coronary heart disease: Narrower coronary arteries near the heart.
Article excerpts about the causes of Coronary heart disease:

Facts About Heart Disease and Women: NHLBI (Excerpt)

Coronary heart disease, the most common form of heart disease, develops over many years. It can begin as far back as childhood. In a process known as atherosclerosis, fatty substances build up inside the walls of blood vessels. Blood components also stick on the surface inside vessel walls. The vessels narrow and "harden," becoming less flexible. The buildup and narrowing proceed gradually and result in decreasing blood flow and, eventually, the development of symptoms. But the buildup, or "plaque," may break open and suddenly produce a blood clot, limited blood flow, and symptoms. When blood flow to the heart is reduced, chest pain, or angina, can result. If blood flow is nearly or completely blocked, a heart attack can occur and cause muscle cells in the heart to die. Because the cells cannot be replaced, the result is permanent heart damage. (Source: excerpt from Facts About Heart Disease and Women: NHLBI)

NHLBI, coronary heart disease: NHLBI (Excerpt)

Like any muscle, the heart needs a constant supply of oxygen and nutrients that are carried to it by the blood in the coronary arteries. When the coronary arteries become narrowed or clogged and cannot supply enough blood to the heart, the result is CHD. If not enough oxygen-carrying blood reaches the heart, the heart may respond with pain called angina. The pain is usually felt in the chest or sometimes in the left arm and shoulder. (However, the same inadequate blood supply may cause no symptoms, a condition called silent angina.) (Source: excerpt from NHLBI, coronary heart disease: NHLBI)

NHLBI, coronary heart disease: NHLBI (Excerpt)

CHD is caused by a thickening of the inside walls of the coronary arteries. This thickening, called atherosclerosis, narrows the space through which blood can flow, decreasing and sometimes completely cutting off the supply of oxygen and nutrients to the heart.

Atherosclerosis usually occurs when a person has high levels of cholesterol, a fat-like substance, in the blood. Cholesterol and fat, circulating in the blood, build up on the walls of the arteries. The buildup narrows the arteries and can slow or block the flow of blood. When the level of cholesterol in the blood is high, there is a greater chance that it will be deposited onto the artery walls. This process begins in most people during childhood and the teenage years, and worsens as they get older.

In addition to high blood cholesterol, high blood pressure and smoking also contribute to CHD. On the average, each of these doubles your chance of developing heart disease. Therefore, a person who has all three risk factors is eight times more likely to develop heart disease than someone who has none. Obesity and physical inactivity are other factors that can lead to CHD. Overweight increases the likelihood of developing high blood cholesterol and high blood pressure, and physical inactivity increases the risk of heart attack. Regular exercise, good nutrition, and smoking cessation are key to controlling the risk factors for CHD. (Source: excerpt from NHLBI, coronary heart disease: NHLBI)

Medical news summaries relating to Coronary heart disease:

The following medical news items are relevant to causes of Coronary heart disease:

• Aneurysms cause sudden heart death
• Atkins diet during pregnancy produces offspring who are less prone to coronary heart disease
• Breastfeeding lowers blood pressure
• Certain oils have protective effect against arrhythmias
• Familial hypercholesterolemia
• High blood pressure may be improved by meditation
• Kawasaki disease effects reduced with steroid treatment
• Metabolic syndrome can be treated with a low carbohydrate diet and exercise
• Oral estrogen directly increases the risk of ovarian cancer
• Shortened life expectancy with hypertension
• Wrongful Death suit filed against doctor
• More news »

Cause statistics for Coronary heart disease:

The following are statistics from various sources about the causes of Coronary heart disease:

• About 22% of global cases of CHD is caused by physical inactivity (WHO World Health Report, 2002)
• Cancer was an underlying cause in 3.0% of female deaths from coronary heart disease in Australia 1997-2002 (AIHW National Morbidity Database, Australia’s Health 2004, AIHW)
• Coronary heart disease was an underlying cause in 73.3% of female deaths from coronary heart disease in Australia 1997-2002 (AIHW National Morbidity Database, Australia’s Health 2004, AIHW)
• Endocrine disease was an underlying cause in 22.4% of female deaths from coronary heart disease in Australia 1997-2002 (AIHW National Morbidity Database, Australia’s Health 2004, AIHW)
• Respiratory disease was an underlying cause in 4.6% of female deaths from coronary heart disease in Australia 1997-2002 (AIHW National Morbidity Database, Australia’s Health 2004, AIHW)
• Stroke was an underlying cause in 11.1% of female deaths from coronary heart disease in Australia 1997-2002 (AIHW National Morbidity Database, Australia’s Health 2004, AIHW)
• Cancer was an underlying cause in 4.3% of male deaths from coronary heart disease in Australia 1997-2002 (AIHW National Morbidity Database, Australia’s Health 2004, AIHW)
• Coronary heart disease was an underlying cause in 70.4% of male deaths from coronary heart disease in Australia 1997-2002 (AIHW National Morbidity Database, Australia’s Health 2004, AIHW)
• Endocrine disease was an underlying cause in 23.6% of male deaths from coronary heart disease in Australia 1997-2002 (AIHW National Morbidity Database, Australia’s Health 2004, AIHW)
• Respiratory disease was an underlying cause in 4.2% of male deaths from coronary heart disease in Australia 1997-2002 (AIHW National Morbidity Database, Australia’s Health 2004, AIHW)
• Stroke was an underlying cause in 12.3% of male deaths from coronary heart disease in Australia 1997-2002 (AIHW National Morbidity Database, Australia’s Health 2004, AIHW)
• 152 women per 100,000 people are hospitalised for coronary heart disease associated with diabetes in Australia 1998-99 (Australia’s Health 2004, AIHW)
• 268 men per 100,000 people are hospitalised for coronary heart disease associated with diabetes in Australia 1998-99 (Australia’s Health 2004, AIHW)
• Diabetes was the associated cause of death in 24% of coronary heart disease deaths in Australia, 2002 (Australia’s Health 2004, AIHW)
• 50% of deaths from diabetes also had heart disease as an associated cause of death in Australia, 2002 (Australia’s Health 2004, AIHW)
• more statistics...»

Related information on causes of Coronary heart disease:

As with all medical conditions, there may be many causal factors. Further relevant information on causes of Coronary heart disease may be found in:

• Risk factors for Coronary heart disease
• Hidden causes of Coronary heart disease

Causes of Coronary heart disease: Online Medical Books

16 MEDICAL BOOKS ONLINE! Review excerpts from medical books online, free, without registration, for more information about the causes of Coronary heart disease.

Coronary artery disease: Causes and incidence
(Professional Guide to Diseases (Eighth Edition))

Atherosclerosis is the usual cause of CAD. In this form of arteriosclerosis, fatty, fibrous plaques, possibly including calcium deposits, narrow the lumen of the coronary arteries, reduce the volume of blood that can flow through them, and lead to myocardial ischemia. Plaque formation also predisposes to thrombosis, which can provoke myocardial infarction (MI).

Atherosclerosis usually develops in high-flow, high-pressure arteries, such as those in the heart, brain, kidneys, and in the aorta, especially at bifurcation points. It has been linked to many risk factors: family history, male gender, age (risk increased in those aged 65 or older), hypertension, obesity, smoking, diabetes mellitus, stress, sedentary lifestyle, high serum cholesterol (particularly high low-density lipoprotein cholesterol) or triglyceride levels, low high-density lipoprotein cholesterol levels, high blood homocysteine levels, menopause and, possibly, infections producing inflammatory responses in the artery walls.

Uncommon causes of reduced coronary artery blood flow include dissecting aneurysms, infectious vasculitis, syphilis, and congenital defects in the coronary vascular system. Coronary artery spasms may also impede blood flow. (See Coronary artery spasm.)

Coronary artery disease is the leading cause of death in the United States. According to the American Heart Association, someone in the United States suffers a coronary heart event approximately every 29 seconds, and someone dies from such an event approximately every 60 seconds.

» READ BOOK EXCERPT ONLINE »

Source: Professional Guide to Diseases (Eighth Edition), 2005

Coronary artery disease: Causes
(Handbook of Diseases)

Atherosclerosis is the usual cause of CAD. In this form of arteriosclerosis, fatty, fibrous plaques narrow the lumen of the coronary arteries, reduce the volume of blood that can flow through them, and lead to myocardial ischemia. Plaque formation also predisposes to thrombosis, which can provoke myocardial infarction (MI).

Atherosclerosis usually develops in high-flow, high-pressure arteries, such as those in the heart, brain, kidneys, and aorta, especially at bifurcation points. It has been linked to many risk factors: family history, hypertension, obesity, smoking, diabetes mellitus, stress, a sedentary lifestyle, and high serum cholesterol and triglyceride levels.

Uncommon causes of reduced coronary artery blood flow include dissecting aneurysms, infectious vasculitis, syphilis, and congenital defects in the coronary vascular system. Coronary artery spasms may also impede blood flow. (See Coronary artery spasm.)

» READ BOOK EXCERPT ONLINE »

Source: Handbook of Diseases, 2003

Anomalous Coronary Artery: Anomalous Coronary Artery - pathophysiology
(The 5-Minute Pediatric Consult)

• Collateral flow runoff tends to “steal” blood from the myocardial blood vessels into the pulmonary artery, resulting in myocardial ischemia.
• The diastolic BP in the pulmonary artery is typically much lower than the main driving force for myocardial perfusion in patients with normal anatomy, namely, diastolic aortic pressure.
• The fact that the left ventricle may be perfused with desaturated blood plays a less important role than the overall perfusion-related imbalance between myocardial oxygen demand and supply.

Anomalous Coronary Artery - etiology

• Abnormal septation of the conotruncus into aorta and pulmonary artery
• Persistence of the pulmonary buds and involution of the aortic buds that will eventually form the coronary arteries
• As-yet-unspecified genetic predisposition

» READ BOOK EXCERPT ONLINE »

Source: The 5-Minute Pediatric Consult, 2008

 » Next page: Risk Factors for Coronary heart disease

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