Prevalence and Incidence of Crohn's disease

Prevalence/Incidence of Crohn's disease: Online Medical Books

16 MEDICAL BOOKS ONLINE! Review excerpts from medical books online, free, without registration, for more information about the prevalence and/or incidence of Crohn's disease.

Crohn's disease: Causes and incidence
(Professional Guide to Diseases (Eighth Edition))

In Crohn’s disease, lacteal blockage in the intestinal wall leads to edema and, eventually, inflammation, ulceration, and stenosis. Abscesses and fistulas may also occur.

Although the exact cause of Crohn’s disease is unknown, autoimmune and genetic factors are thought to play a role. Up to 5% of those with the disease have one or more affected relatives; Jewish ancestry is also a risk factor. However, a pattern of Mendelian inheritance hasn’t been identified.

The incidence of Crohn’s disease has risen steadily over the past 50 years; it now affects 7 out of every 100,000 people. Crohn’s disease is most prevalent in adults ages 20 to 40. It’s two to three times more common in those of Jewish ancestry and least common in blacks.

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Source: Professional Guide to Diseases (Eighth Edition), 2005

Crohn Disease: Crohn Disease - epidemiology
(The 5-Minute Pediatric Consult)

• More than 1/3 of patients 1st present in childhood or adolescence.
• Family history is present in 30% of patients <30 years old.
• In adulthood, Male = Female; in childhood, Male > Female (1.6:1)

Crohn Disease - incidence

• The incidence rate in children is 4.56/100,000 in North America.
• Highest incidence in the white population

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Source: The 5-Minute Pediatric Consult, 2008

About prevalence and incidence statistics:

The term 'prevalence' of Crohn's disease usually refers to the estimated population of people who are managing Crohn's disease at any given time. The term 'incidence' of Crohn's disease refers to the annual diagnosis rate, or the number of new cases of Crohn's disease diagnosed each year. Hence, these two statistics types can differ: a short-lived disease like flu can have high annual incidence but low prevalence, but a life-long disease like diabetes has a low annual incidence but high prevalence. For more information see about prevalence and incidence statistics.

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