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Prevalence and Incidence of Cushing's symphalangism

Cushing's symphalangism: Rare Disease

Cushing's symphalangism is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH). This means that Cushing's symphalangism, or a subtype of Cushing's symphalangism, affects less than 200,000 people in the US population.

Ophanet, who are a consortium of European partners, currently defines a condition rare when if affects 1 person per 2,000. They list Cushing's symphalangism as a "rare disease". More information about Cushing's symphalangism is available from Orphanet

Cushing's symphalangism Prevalence: Book Excerpts

Prevalence/Incidence of Cushing's symphalangism: Online Medical Books

16 MEDICAL BOOKS ONLINE! Review excerpts from medical books online, free, without registration, for more information about the prevalence and/or incidence of Cushing's symphalangism.

Cushing's syndrome: Causes and incidence
(Professional Guide to Diseases (Eighth Edition))

In approximately 70% of patients, Cushing’s syndrome results from excessive production of corticotropin and consequent hyperplasia of the adrenal cortex. Overproduction of corticotropin may stem from pituitary hypersecretion (Cushing’s disease), a corticotropin-producing tumor in another organ (particularly bronchogenic or pancreatic cancer), or excessive administration of exogenous glucocorticoids.

In the remaining 30% of patients, Cushing’s syndrome results from a cortisol-secreting adrenal tumor, which is usually benign. In infants, the usual cause of Cushing’s syndrome is adrenal carcinoma.

Cushing’s syndrome affects 13 of every 1 million people. It’s more common in females than in males and occurs primarily between ages between ages 25 and 40.

» READ BOOK EXCERPT ONLINE »

Source: Professional Guide to Diseases (Eighth Edition), 2005

About prevalence and incidence statistics:

The term 'prevalence' of Cushing's symphalangism usually refers to the estimated population of people who are managing Cushing's symphalangism at any given time. The term 'incidence' of Cushing's symphalangism refers to the annual diagnosis rate, or the number of new cases of Cushing's symphalangism diagnosed each year. Hence, these two statistics types can differ: a short-lived disease like flu can have high annual incidence but low prevalence, but a life-long disease like diabetes has a low annual incidence but high prevalence. For more information see about prevalence and incidence statistics.


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