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Diseases » Cytomegalovirus » Symptoms
 

Symptoms of Cytomegalovirus

Symptoms of Cytomegalovirus

The list of signs and symptoms mentioned in various sources for Cytomegalovirus includes the 20 symptoms listed below:

Research symptoms & diagnosis of Cytomegalovirus:

Cytomegalovirus: Complications

Review medical complications possibly associated with Cytomegalovirus:

Cytomegalovirus Symptoms: Book Excerpts

Diagnostic Testing

Diagnostic testing of medical conditions related to Cytomegalovirus:

Research More About Cytomegalovirus

Do I have Cytomegalovirus?

Cytomegalovirus: Medical Mistakes

Cytomegalovirus: Undiagnosed Conditions

Diseases that may be commonly undiagnosed in related medical areas:

Home Diagnostic Testing

Home medical tests related to Cytomegalovirus:

Wrongly Diagnosed with Cytomegalovirus?

The list of other diseases or medical conditions that may be on the differential diagnosis list of alternative diagnoses for Cytomegalovirus includes:

See the full list of 18 alternative diagnoses for Cytomegalovirus

More about symptoms of Cytomegalovirus:

More information about symptoms of Cytomegalovirus and related conditions:

Other Possible Causes of these Symptoms

Click on any of the symptoms below to see a full list of other causes including diseases, medical conditions, toxins, drug interactions, or drug side effect causes of that symptom.

Medical Books Online about Cytomegalovirus

Medical Books Excerpts Excerpts of published medical book chapters related to Cytomegalovirus are available from published medical books for more detailed information about Cytomegalovirus.

Medical Books Excerpts

Copyright notice for book excerpts: Copyright © 2008 Lippincott Williams & Wilkins. All rights reserved.

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Symptoms of Cytomegalovirus: Online Medical Books

16 MEDICAL BOOKS ONLINE! Review excerpts from medical books online, free, without registration, for more information about the symptoms of Cytomegalovirus.


Genital herpes: Signs and symptoms
(Professional Guide to Diseases (Eighth Edition))

After a 3- to 7-day incubation period, fluid-filled vesicles appear, usually on the cervix (the primary infection site) and possibly on the labia, perianal skin, vulva, or vagina of the female and on the glans penis, foreskin, or penile shaft of the male. Extragenital lesions may appear on the mouth or anus. In both males and females, the vesicles, usually painless at first, will rupture and develop into extensive, shallow, painful ulcers, with redness, marked edema, tender inguinal lymph nodes, and the characteristic yellow, oozing centers.

Other features of initial mucocutaneous infection include fever, malaise, dysuria and, in females, leukorrhea. Rare complications (generally from extragenital lesions) include herpetic keratitis, which may lead to blindness, and potentially fatal herpetic encephalitis.

» READ BOOK EXCERPT ONLINE »

Source: Professional Guide to Diseases (Eighth Edition), 2005

Herpes simplex: Signs and symptoms
(Professional Guide to Diseases (Eighth Edition))

In neonates, HVH symptoms usually appear 1 to 2 weeks after birth. They range from localized skin lesions to a disseminated infection of organs, such as the liver, lungs, or brain. Common complications include seizures, mental retardation, blindness, chorioretinitis, deafness, microcephaly, diabetes insipidus, and spasticity. Up to 90% of infants with disseminated disease die.

Primary infection in childhood may be localized or generalized and occurs after an incubation period of 2 to 12 days. After brief prodromal tingling and itching, localized infection causes typical primary lesions. These erupt as vesicles on an erythematous base, eventually rupture and leave a painful ulcer, followed by a yellowish crust. Vesicles may form on any part of the oral mucosa, especially the tongue, gingiva, and cheeks. Healing begins 7 to 10 days after onset and is complete in 3 weeks.

Generalized infection begins with fever, pharyngitis, erythema, and edema. Vesicles occur with submaxillary lymphadenopathy, increased salivation, halitosis, anorexia, and a fever of up to 105° F (40.6° C). Herpetic stomatitis may lead to severe dehydration in children. A generalized infection usually runs its course in 4 to 10 days. In this form, virus reactivation causes cold sores — a single or group of vesicles in and around the mouth.

Genital herpes usually affects adolescents and young adults. Typically painful, the initial attack produces fluid-filled vesicles that ulcerate and heal in 1 to 3 weeks. Fever, regional lymphadenopathy, and dysuria may also occur.

Usually, herpetic keratoconjunctivitis is unilateral and causes only local signs and symptoms: conjunctivitis, regional adenopathy, blepharitis, and vesicles on the lid. Other ocular effects may include excessive lacrimation, edema, chemosis, photophobia, and purulent exudate.

Both types of HVH can cause acute sporadic encephalitis with altered level of consciousness, personality changes, and seizures. Other effects may include smell and taste hallucinations and neurologic abnormalities such as aphasia.

Herpetic whitlow, an HVH finger infection, affects many nurses. First the finger tingles and then it becomes red, swollen, and painful. Vesicles with a red halo erupt and may ulcerate or coalesce. Other effects may include satellite vesicles, fever, chills, malaise, and a red streak up the arm.

» READ BOOK EXCERPT ONLINE »

Source: Professional Guide to Diseases (Eighth Edition), 2005

Cytomegalovirus infection: Signs and symptoms
(Professional Guide to Diseases (Eighth Edition))

CMV probably spreads through the body in lymphocytes or mononuclear cells to the lungs, liver, GI tract, eyes, and central nervous system, where it commonly produces inflammatory reactions.

Most patients with CMV infection have mild, nonspecific complaints or none at all, even though antibody titers indicate infection. In these patients, the disease usually runs a self-limiting course. However, immunodeficient patients and those receiving immunosuppressants may develop pneumonia or other secondary infections. In patients with acquired immunodeficiency syndrome, disseminated CMV infection may cause chorioretinitis (resulting in blindness), colitis, encephalitis, abdominal pain, diarrhea, or weight loss. Infected infants ages 3 to 6 months usually appear asymptomatic but may develop hepatic dysfunction, hepatosplenomegaly, spider angiomas, pneumonitis, and lymphadenopathy.

Congenital CMV infection is seldom apparent at birth, although the neonate’s urine contains the virus. CMV can cause brain damage that may not show up for months after birth. It also can produce a rapidly fatal neonatal illness characterized by jaundice, petechial rash, hepatosplenomegaly, thrombocytopenia, hemolytic anemia, microcephaly, psychomotor retardation, mental deficiency, and hearing loss. Occasionally, this form is rapidly fatal.

In some adults, CMV may cause cytomegalovirus mononucleosis, with 3 weeks or more of irregular, high fever. Other findings may include a normal or elevated white blood cell (WBC) count, lymphocytosis, and increased atypical lymphocytes.

» READ BOOK EXCERPT ONLINE »

Source: Professional Guide to Diseases (Eighth Edition), 2005

Herpes simplex: Signs and symptoms
(Handbook of Diseases)

Primary infection in childhood may be generalized or localized.

In neonates, HVH symptoms usually appear 1 to 2 weeks after birth. They range from localized skin lesions to a disseminated infection of such organs as the liver, lungs, and brain. Common complications include seizures, mental retardation, blindness, chorioretinitis, deafness, microcephaly, diabetes insipidus, and spasticity. Neonates with disseminated disease have a high mortality.

Generalized infection

After an incubation period of 2 to 12 days, onset of generalized infection begins with fever, pharyngitis, erythema, and edema. After brief prodromal tingling and itching, typical primary lesions erupt as vesicles on an erythematous base, eventually rupturing and leaving a painful ulcer, followed by a yellowish crust. Healing begins 7 to 10 days after onset and is complete in 3 weeks.

Vesicles may form on any part of the oral mucosa, especially the tongue, gingiva, and cheeks. In generalized infection, vesicles occur with submaxillary lymphadenopathy, increased salivation, halitosis, anorexia, and a temperature as high as 105° F (40.6° C). Herpetic stomatitis may lead to severe dehydration in children.

A generalized infection usually runs its course in 4 to 10 days. In this form, virus reactivation causes cold sores — single or grouped vesicles in and around the mouth.

Localized infection

Genital herpes usually affects adolescents and young adults. Typically painful, the initial attack produces fluid-filled vesicles that ulcerate and heal in 1 to 3 weeks. Fever, regional lymphadenopathy, and dysuria may also occur.

Usually, herpetic keratoconjunctivitis is unilateral and causes only local symptoms, including conjunctivitis, regional adenopathy, blepharitis, and vesicles on the lid. Other ocular symptoms may be excessive lacrimation, edema, chemosis, photophobia, and purulent exudate.

Other signs and symptoms

Both types of HVH can cause acute sporadic encephalitis with an altered level of consciousness, personality changes, and seizures. Other effects include smell and taste hallucinations and neurologic abnormalities such as aphasia.

Herpetic whitlow, an HVH finger infection, commonly affects health care workers. First, the finger tingles and then it becomes red, swollen, and painful. Vesicles with a red halo erupt and may ulcerate or coalesce. Other effects may include satellite vesicles, fever, chills, malaise, and a red streak up the arm.

» READ BOOK EXCERPT ONLINE »

Source: Handbook of Diseases, 2003

Cytomegalovirus infection: Signs and symptoms
(Handbook of Diseases)

CMV probably spreads through the body in lymphocytes or mononuclear cells to the lungs, liver, GI tract, eyes, and central nervous system, where it commonly produces inflammatory reactions.

Most patients with CMV infection have mild, nonspecific complaints, or none at all, even though antibody titers indicate infection. In these patients, the disease usually runs a self-limiting course.

Immunodeficient patients, such as those with acquired immunodeficiency syndrome (AIDS), and those receiving immunosuppressants may develop pneumonia or other secondary infections. AIDS patients may also develop disseminated CMV infection, which may cause chorioretinitis (resulting in blindness), colitis, or encephalitis.

Infected infants ages 3 to 6 months usually appear asymptomatic but may develop hepatic dysfunction, hepatosplenomegaly, spider angiomas, pneumonitis, and lymphadenopathy.

Congenital CMV infection is seldom apparent at birth, although the infant’s urine contains CMV. About 1% of all newborns have CMV.

The virus can cause brain damage that may not show up for months after birth. Occasionally, it produces a rapidly fatal neonatal illness characterized by jaundice, petechial rash, hepatosplenomegaly, thrombocytopenia, hemolytic anemia, microcephaly, psychomotor retardation, mental deficiency, and hearing loss.

In some adults, CMV may cause cytomegalovirus mononucleosis, with 3 weeks or more of irregular, high fever.

Other findings may include a normal or elevated white blood cell (WBC) count, lymphocytosis, and increased atypical lymphocytes.

» READ BOOK EXCERPT ONLINE »

Source: Handbook of Diseases, 2003

Smallpox (Variola Virus): Smallpox - signs & symptoms
(The 5-Minute Pediatric Consult)

  • Ordinary smallpox:
    • Incubation period of 7–17 days is followed by febrile prodrome lasting 1–4 days.
      • The prodrome is characterized by high fever, headache, back pain, chills, abdominal pain, and emesis.
    • Eruptive phase begins with lesions of the mouth, tongue and oropharynx.
    • Then the rash develops:
      • Often starts on face and spreads to rest of body within 24–48 hours.
      • On day 1 the rash is macular.
      • On day 2 the rash becomes papular.
      • On days 4–5 the rash is vesicular.
      • By day 7 the rash has become pustular.
      • By 2–3 weeks the scabs have formed.
      • Scabs fall off and leave scars.
  • Modified smallpox:
    • Milder than ordinary smallpox
    • Accelerated course
    • Lesions are not as deep.
  • Flat smallpox:
    • Characterized by a soft, flat, semiconfluent or confluent rash that does not progress to pustules
    • Can result in significant skin loss
  • Hemorrhagic smallpox:
    • Shorter incubation time.
    • Skin becomes dusky.
    • Bleeding occurs in the skin and mucous membranes.
    • Can be difficult to diagnose unless exposure to variola virus is known
  • Variola Sine Eruptione:
    • May be asymptomatic or cause a febrile influenzalike illness
    • Noncontagious
    • Seen in infants with protective maternal antibodies and in vaccinated individuals
  • If there has not been a release or circulation of smallpox the CDC Protocol for evaluating patients for smallpox can be used to guide the assessment of a suspicious rash illness.
  • CDC protocol for evaluating patients for smallpox:
    • If a patient has an acute, generalized rash on the body, with vesicles or pustules:
      • Use the major and minor criteria to assess the likelihood of smallpox.
    • Major criteria:
      • Febrile prodrome: 1–4 days prior to rash onset including a temperature ≥101°F and 1 or more of the following: Prostration, headache, backache, chills, vomiting or severe abdominal pain
      • Classic smallpox lesions: Deep-seated, firm/hard, round, well-circumscribed vesicles or pustules. Can become umbilicated or confluent as they evolve.
      • On any one part of the body (e.g., the face or arm) all the lesions are in the same stage of development.
    • Minor criteria:
      • Centrifugal distribution: Greatest concentration of lesions on face and extremities
      • 1st lesions appear on the oral mucosa, palate, face, or forearms.
      • Patient appears toxic or moribund.
      • Slow evolution: Lesions evolve from macules to papules to pustules over days (each stage lasts 1–2 days).
      • Lesions on the palms and soles
    • High risk of smallpox:
      • Febrile prodrome and classic smallpox lesions in same stage of development
    • Moderate risk of smallpox:
      • Febrile prodrome and 1 other major smallpox criterion
      • Or febrile prodrome and ≥4 minor smallpox criteria
    • Low risk of smallpox:
      • No febrile prodrome
      • Or febrile prodrome and <4 minor smallpox criteria
  • Online tool for evaluation risk of smallpox is available at http://www.bt.cdc.gov/agent/smallpox/diagnosis/riskalgorithm/
>

» READ BOOK EXCERPT ONLINE »

Source: The 5-Minute Pediatric Consult, 2008

Article Excerpts About Symptoms of Cytomegalovirus:

NINDS Cytomegalic Inclusion Body Disease (CIBD) Information Page: NINDS (Excerpt)

Many children and adults who acquire the infection show no symptoms of the disease. But some, especially those who are immune compromised, may show serious symptoms, including fever, hepatitis, pneumonitis, retinitis, and/or a mononucleosis-like illness. In immune-compromised individuals, particularly those with AIDS, CMV infection can cause encephalitis. CMV is also a concern in organ-transplant populations-for example, those who receive kidney, heart, or lung transplants. Fetuses and newborn babies may acquire CMV before or during birth from a mother with an active infection. In these cases, the virus can be lethal to the fetus or newborn baby or cause serious systemic problems, including pneumonitis, bleeding, anemia, liver damage, or brain damage. (Source: excerpt from NINDS Cytomegalic Inclusion Body Disease (CIBD) Information Page: NINDS)

Other Important STDS, NIAID Fact Sheet: NIAID (Excerpt)

In healthy adults, CMV usually produces no symptoms of infection. Occasionally, however, mild symptoms of swollen lymph glands, fever, and fatigue may occur. These symptoms may be similar to those of infectious mononucleosis. (Source: excerpt from Other Important STDS, NIAID Fact Sheet: NIAID)

Cytomegalovirus (CMV) Infection: DVRD (Excerpt)

For most healthy persons who acquire CMV after birth there are few symptoms and no long-term health consequences. Some persons with symptoms experience a mononucleosis-like syndrome with prolonged fever, and a mild hepatitis. Once a person becomes infected, the virus remains alive, but usually dormant within that person's body for life. Recurrent disease rarely occurs unless the person's immune system is suppressed due to therapeutic drugs or disease. Therefore, for the vast majority of people, CMV infection is not a serious problem. (Source: excerpt from Cytomegalovirus (CMV) Infection: DVRD)

Cytomegalovirus as a Cause of Symptoms or Medical Conditions

When considering symptoms of Cytomegalovirus, it is also important to consider Cytomegalovirus as a possible cause of other medical conditions. The Disease Database lists the following medical conditions that Cytomegalovirus may cause:

- (Source - Diseases Database)

Medical articles and books on symptoms:

These general reference articles may be of interest in relation to medical signs and symptoms of disease in general:

Full list of premium articles on symptoms and diagnosis

About signs and symptoms of Cytomegalovirus:

The symptom information on this page attempts to provide a list of some possible signs and symptoms of Cytomegalovirus. This signs and symptoms information for Cytomegalovirus has been gathered from various sources, may not be fully accurate, and may not be the full list of Cytomegalovirus signs or Cytomegalovirus symptoms. Furthermore, signs and symptoms of Cytomegalovirus may vary on an individual basis for each patient. Only your doctor can provide adequate diagnosis of any signs or symptoms and whether they are indeed Cytomegalovirus symptoms.


 » Next page: Diagnostic Tests for Cytomegalovirus

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