Clinical Trials for Death

Clinical trials are research studies conducted in an effort to improve overall patient health and care. Each trial involves running supervised tests to determine the effectiveness and safety of new drugs, procedures and/or devices with the aim of answering scientific questions about a disease or condition. Risks and side-effects are also evaluated during these trials with results ranging from being unpleasant, with side effects such as headaches, to more serious or even life-threatening risks. A clinical trial may be separated into phases, or steps, with each step designed to answer a separate research question. This maybe reflected in the trial name.

A brief description of each phase:

• Phase I: Usually designed to evaluate safety, determine a safe dosage range, and identify side effects on a small group of patients.
• Phase II: If Phase I is successful, the trial is then repeated with a larger group to further evaluate its effect and safety.
• Phase III: Trials are conducted on an ever larger group and are compared with the best current treatment while gathering more information on effect and safety.
• Phase IV: These studies monitor long-term side effects after the treatment has been marketed.

Clinical Trials data for Death is grouped into the following categories:-

• View by trial name
• View by drugs used in Death clinical trials

Clinical Trials by trial name

The format for each of the following is:

• The name of the trial,
• followed by whether the trial is recruiting patients,
  - The trial may not have started and not yet recruiting, or the trial may have started and do not need any more recruitements, or the trial may be completed.
  - Note**: Please follow the link to determine the current trial status.
• followed by a list of drug/s, if any, used in the trial

ClinicalTrials.gov has listed the following trials for Death:

• Assessment of Noninvasive Methods to Identify Patients at Risk of Serious Arrhythmias After a Heart Attack - This study has been completed (Current: 23 Nov 2006)
• CORE: Study to Evaluate the Conducted AF-Response-Algorithm in Patients Suffering From Heart Failure and Atrial Fibrillation - This study is currently recruiting patients (Current: 23 Nov 2006)
• RAMYD Study - Evaluation of Arrhythmic Risk in Myotonic Dystrophy - This study is currently recruiting patients (Current: 23 Nov 2006)
• Influence of Pacifiers on Breastfeeding Duration: a Multicentre, Randomised Controlled Trial - This study is currently recruiting patients (Current: 23 Nov 2006)
• Treatment of Ventricular Tachyarrhythmias Refractory To Shock With Beta Blockers: The SHOCK and BLOCK Trial - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - Metoprolol
• Incidence and Severity of Cardiorespiratory Events in Infants at Increased Epidemiological Risk for Sudden Infant Death Syndrome (SIDS) - This study has been completed (Current: 23 Nov 2006)
• The Effect of Nebulized Albuterol on Donor Oxygenation - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - Albuterol
• Risk Indicators in Patients With Ventricular Fibrillation During Acute Myocardial Infarction - This study is currently recruiting patients (Current: 23 Nov 2006)
• Imaging Techniques for Identifying Factors of Sudden Cardiac Death Risk - This study is currently recruiting patients (Current: 23 Nov 2006)
• DAVID II (Dual Chamber and VVI Implantable Defibrillator (DAVID) Trial II) - This study is no longer recruiting patients (Current: 23 Nov 2006)
• POWER (Pulse Width Optimized Waveform Evaluation Trial) - This study is currently recruiting patients (Current: 23 Nov 2006)
• Long-Term Outcomes of Patients After Coronary Bifurcation Stenting - This study has been completed (Current: 23 Nov 2006)
• Multicenter Unsustained Tachycardia Trial (MUSTT) - This study has been completed (Current: 23 Nov 2006) - anti-arrhythmia agents
• Beta-Blocker Heart Attack Trial (BHAT) - This study has been completed (Current: 23 Nov 2006) - propranolol
• Electrophysiologic Study Versus Electrocardiographic Monitoring (ESVEM) - This study has been completed (Current: 23 Nov 2006) - imipramine,mexiletine,procainamide,quinidine,sotalol
• Diuretics, Hypertension, and Arrhythmias Clinical Trial - This study has been completed (Current: 23 Nov 2006) - hydrochlorothiazide,triamterene,chlorthalidone
• Cardiac Arrhythmia Suppression Trial (CAST) - This study has been completed (Current: 23 Nov 2006) - encainide,flecainide,moricizine
• Antiarrhythmics Versus Implantable Defibrillators (AVID) - This study has been completed (Current: 23 Nov 2006) - amiodarone amiodarone,sotalol
• Coronary Artery Bypass Graft (CABG) Patch Trial - This study has been completed (Current: 23 Nov 2006)
• Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT) - This study has been completed (Current: 23 Nov 2006) - amiodarone
• Public Access Defibrillation (PAD) Community Trial - This study has been completed (Current: 23 Nov 2006)
• Identifying High Risk Patients With Syncope - This study has been completed (Current: 23 Nov 2006)
• Incidence of Diabetes and Cardiovascular Disease in Mexican Americans - This study has been completed (Current: 23 Nov 2006)
• Heart Rate Variability and Sudden Cardiac Death - This study has been completed (Current: 23 Nov 2006)
• Natural History of Coronary Heart Disease - This study has been completed (Current: 23 Nov 2006)
• Novel Hemostatic Cardiac Risk Factors in Framingham - This study has been completed (Current: 23 Nov 2006)
• Thrombogenic Factors and Recurrent Coronary Events - This study has been completed (Current: 23 Nov 2006)
• Epidemiology of Long QTand Asian Sudden Death in Sleep - This study has been completed (Current: 23 Nov 2006)
• Epidemiology of Cardiotoxicity in Children With Cancer - This study has been completed (Current: 23 Nov 2006)
• Anxiety and Vagal Control of the Heart in Coronary Disease - This study has been completed (Current: 23 Nov 2006)
• Minnesota Heart Survey - Mortality and Morbidity - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Prognostic Significance of T Wave Alternans - This study has been completed (Current: 23 Nov 2006)
• Home Use of Automatic External Defibrillators to Treat Sudden Cardiac Arrest - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Genetic Determinants of Sudden Cardiac Death - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Drug-Induced Sudden Death & Ventricular Arrhythmia - This study is no longer recruiting patients (Current: 23 Nov 2006)
• ResQ Trial: Impact of an ITD and Active Compression Decompression CPR on Survival From Out-of-Hospital Cardiac Arrest - This study is currently recruiting patients (Current: 23 Nov 2006)
• Medications and the Risk of Sudden Cardiac Death - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Extracellular Matrix Marker of Arrhythmia Risk (EMMA) - This study is currently recruiting patients (Current: 23 Nov 2006)
• Automatic External Defibrillation Monitoring in Cardiac Arrest - This study is currently recruiting patients (Current: 23 Nov 2006)
• "Death Rattle" A Double Blind, Randomly Controlled, Crossover Trial - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - Atropine Sulphate 1% ophthalmic drops
• Parental Knowledge and Beliefs About Infant Sleep Position - This study has been completed (Current: 23 Nov 2006)
• Thyroxine Replacement in Organ Donors - This study is currently recruiting patients (Current: 23 Nov 2006) - L-thryoxine
• Comparing the Effects of Amiodarone, Sotalol, and Placebo in Maintaining Sinus Rhythm in Patients With Atrial Fibrillation Converted to Sinus Rhythm - This study has been completed (Current: 23 Nov 2006) - Amiodarone,Sotalol
• The Use of Nesiritide in Thoracic Aneurysm Repair to Prevent Acute Renal Failure - This study is currently recruiting patients (Current: 23 Nov 2006) - Nesiritide
• Trial of Aggressive Versus Conservative Phototherapy in Infants < 1000 Grams Birthweight - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Long Term Use of Valganciclovir for Prophylaxis of CMV Disease in Kidney and Pancreas Transplant Patients - This study has been completed (Current: 23 Nov 2006)
• Intervention to Improve Care at Life's End - This study is currently recruiting patients (Current: 23 Nov 2006)
• Protective Ventilatory Strategy in Potential Organ Donors - This study is currently recruiting patients (Current: 23 Nov 2006)
• Protective Effect of EPA on Cardiovascular Events - This study has been completed (Current: 23 Nov 2006) - Eicosapentaenoic acid ethyl ester(EPADEL Capsule 300 TM)
• Intermittent Preventive Treatment of Malaria in HIV-Seropositive Pregnant Women in Zambia - This study has been completed (Current: 23 Nov 2006) - Sulfadoxine-pyrimethamine (Fansidar)
• Exposure to Neurotoxins as Risk Factors for Amyotrophic Lateral Sclerosis - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Environmental and Behavioral Risk Factors for Childhood Drowning - This study is currently recruiting patients (Current: 23 Nov 2006)
• Isoproterenol Challenge to Detect Arrhythmogenic Right Ventricular Cardiomyopathy - This study has been completed (Current: 23 Nov 2006)
• Spirituality, Religiosity, and Immune Functioning - This study has been completed (Current: 23 Nov 2006)
• Trial of an Interactive CD-Program on 6 Months Readmission Rate in Patients With Heart Failure - This study has been completed (Current: 23 Nov 2006)
• Heart and Skeletal Muscle Problems in Neuroacanthocytosis - This study has been completed (Current: 23 Nov 2006)
• Signs and Symptoms Associated With Molecular Defects in Genetically Inherited Heart Disease - This study has been completed (Current: 23 Nov 2006)
• Heart Disease in Sickle Cell Anemia - This study is currently recruiting patients (Current: 23 Nov 2006)
• Second Canadian Trial of Physiologic Pacing (CTOPP II): Pilot Trial - This study is currently recruiting patients (Current: 23 Nov 2006)
• Very Low Protein Diet and Renal Death in CKD - ERIKA Study - This study is currently recruiting patients (Current: 23 Nov 2006)
• Prognostic Measures in Ambulatory Care Settings - This study has been completed (Current: 23 Nov 2006)
• PREPARE - Primary Prevention Parameters Evaluation - This study is no longer recruiting patients (Current: 23 Nov 2006)
• T Wave Alternans in Hemodialysis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Study to Determine if Atorvastatin Reduces Size and Stiffness of Muscle in the Left Ventricle of the Heart - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - Atorvastatin
• Pediatric Lead Extractability and Survival Evaluation (PLEASE) - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• RED-HF Trial Reduction of Events With Darbepoetin Alfa in Heart Failure Trial - This study is currently recruiting patients (Current: 23 Nov 2006) - Darbepoetin alfa
• Cognitive Therapy for Suicidal Older Men in Primary Care Settings - This study is currently recruiting patients (Current: 23 Nov 2006)
• Study of CS-1008 in Patients With Advanced Solid Malignancies and Lymphomas (Without Leukemic Component) - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - CS-1008 (humanized anti-DR5 antibody)
• Death Following Congenital Heart Surgery - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Intravenous n-3 Fatty Acids and Sudden Cardiac Death in Haemodialysis Patients - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - lipid emulsion with a high content of n-3 fatty acids
• Resynchronization/Defibrillation for Advanced Heart Failure Trial - This study is currently recruiting patients (Current: 23 Nov 2006)
• Study to Improve Care for Veterans During Serious Illness - This study is currently recruiting patients (Current: 23 Nov 2006)
• A Randomized Trial of Two Regimens of Misoprostol for Second Trimester Termination for Intrauterine Fetal Death - This study is currently recruiting patients (Current: 23 Nov 2006) - misoprostol Cytotec®
• Determination of Gentamicin Dosing in Neonatal Patients - This study is no longer recruiting patients (Current: 23 Nov 2006) - Gentamicin in Uniject Pre-filled syringe
• Impact of Prenatal Vitamin/Mineral Supplements on Perinatal Mortality - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• PEEP Test and Gas Exchange in ALI/ARDS Patients - This study is currently recruiting patients (Current: 23 Nov 2006)

Drugs used in Clinical Trials for Death

The format for each of the following is:

• The drug,
• followed by the name of the trial,
• followed by whether the trial is recruiting patients,
  - The trial may not have started and not yet recruiting, or the trial may have started and do not need any more recruitements, or the trial may be completed.
  - Note**: Please follow the link to determine the current trial status.

ClinicalTrials.gov has listed the following drugs in trials for Death:

• Albuterol - The Effect of Nebulized Albuterol on Donor Oxygenation - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Amiodarone Amiodarone - Antiarrhythmics Versus Implantable Defibrillators (AVID) - This study has been completed (Current: 23 Nov 2006)
• Amiodarone - Comparing the Effects of Amiodarone, Sotalol, and Placebo in Maintaining Sinus Rhythm in Patients With Atrial Fibrillation Converted to Sinus Rhythm - This study has been completed (Current: 23 Nov 2006)
• Amiodarone - Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT) - This study has been completed (Current: 23 Nov 2006)
• Anti-Arrhythmia Agents - Multicenter Unsustained Tachycardia Trial (MUSTT) - This study has been completed (Current: 23 Nov 2006)
• Atorvastatin - Study to Determine if Atorvastatin Reduces Size and Stiffness of Muscle in the Left Ventricle of the Heart - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Atropine Sulphate 1% ophthalmic drops - "Death Rattle" A Double Blind, Randomly Controlled, Crossover Trial - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• CS-1008 (humanized anti-DR5 antibody) - Study of CS-1008 in Patients With Advanced Solid Malignancies and Lymphomas (Without Leukemic Component) - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Chlorthalidone - Diuretics, Hypertension, and Arrhythmias Clinical Trial - This study has been completed (Current: 23 Nov 2006)
• Darbepoetin alfa - RED-HF Trial Reduction of Events With Darbepoetin Alfa in Heart Failure Trial - This study is currently recruiting patients (Current: 23 Nov 2006)
• Eicosapentaenoic acid ethyl ester(EPADEL Capsule 300 TM) - Protective Effect of EPA on Cardiovascular Events - This study has been completed (Current: 23 Nov 2006)
• Encainide - Cardiac Arrhythmia Suppression Trial (CAST) - This study has been completed (Current: 23 Nov 2006)
• Flecainide - Cardiac Arrhythmia Suppression Trial (CAST) - This study has been completed (Current: 23 Nov 2006)
• Gentamicin in Uniject Pre-filled syringe - Determination of Gentamicin Dosing in Neonatal Patients - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Hydrochlorothiazide - Diuretics, Hypertension, and Arrhythmias Clinical Trial - This study has been completed (Current: 23 Nov 2006)
• Imipramine - Electrophysiologic Study Versus Electrocardiographic Monitoring (ESVEM) - This study has been completed (Current: 23 Nov 2006)
• L-thryoxine - Thyroxine Replacement in Organ Donors - This study is currently recruiting patients (Current: 23 Nov 2006)
• Lipid Emulsion With A High Content Of N-3 Fatty Acids - Intravenous n-3 Fatty Acids and Sudden Cardiac Death in Haemodialysis Patients - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Metoprolol - Treatment of Ventricular Tachyarrhythmias Refractory To Shock With Beta Blockers: The SHOCK and BLOCK Trial - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Mexiletine - Electrophysiologic Study Versus Electrocardiographic Monitoring (ESVEM) - This study has been completed (Current: 23 Nov 2006)
• Misoprostol Cytotec® - A Randomized Trial of Two Regimens of Misoprostol for Second Trimester Termination for Intrauterine Fetal Death - This study is currently recruiting patients (Current: 23 Nov 2006)
• Moricizine - Cardiac Arrhythmia Suppression Trial (CAST) - This study has been completed (Current: 23 Nov 2006)
• Nesiritide - The Use of Nesiritide in Thoracic Aneurysm Repair to Prevent Acute Renal Failure - This study is currently recruiting patients (Current: 23 Nov 2006)
• Procainamide - Electrophysiologic Study Versus Electrocardiographic Monitoring (ESVEM) - This study has been completed (Current: 23 Nov 2006)
• Propranolol - Beta-Blocker Heart Attack Trial (BHAT) - This study has been completed (Current: 23 Nov 2006)
• Quinidine - Electrophysiologic Study Versus Electrocardiographic Monitoring (ESVEM) - This study has been completed (Current: 23 Nov 2006)
• Sotalol - Antiarrhythmics Versus Implantable Defibrillators (AVID) - This study has been completed (Current: 23 Nov 2006)
• Sotalol - Comparing the Effects of Amiodarone, Sotalol, and Placebo in Maintaining Sinus Rhythm in Patients With Atrial Fibrillation Converted to Sinus Rhythm - This study has been completed (Current: 23 Nov 2006)
• Sotalol - Electrophysiologic Study Versus Electrocardiographic Monitoring (ESVEM) - This study has been completed (Current: 23 Nov 2006)
• Sulfadoxine-pyrimethamine (Fansidar) - Intermittent Preventive Treatment of Malaria in HIV-Seropositive Pregnant Women in Zambia - This study has been completed (Current: 23 Nov 2006)
• Triamterene - Diuretics, Hypertension, and Arrhythmias Clinical Trial - This study has been completed (Current: 23 Nov 2006)

The trial data on this page has been sourced from

• The U.S. National Library of Medicine (NLM) together with ClinicalTrials.gov

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