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Diseases » Dermatomyositis » Clinical Trials

Clinical Trials for Dermatomyositis

Clinical trials are research studies conducted in an effort to improve overall patient health and care. Each trial involves running supervised tests to determine the effectiveness and safety of new drugs, procedures and/or devices with the aim of answering scientific questions about a disease or condition. Risks and side-effects are also evaluated during these trials with results ranging from being unpleasant, with side effects such as headaches, to more serious or even life-threatening risks. A clinical trial may be separated into phases, or steps, with each step designed to answer a separate research question. This maybe reflected in the trial name.

A brief description of each phase:

Phase I: Usually designed to evaluate safety, determine a safe dosage range, and identify side effects on a small group of patients.
Phase II: If Phase I is successful, the trial is then repeated with a larger group to further evaluate its effect and safety.
Phase III: Trials are conducted on an ever larger group and are compared with the best current treatment while gathering more information on effect and safety.
Phase IV: These studies monitor long-term side effects after the treatment has been marketed.

Clinical Trials data for Dermatomyositis is grouped into the following categories:-

View by trial name

View by drugs used in Dermatomyositis clinical trials

Clinical Trials by trial name

The format for each of the following is:

The name of the trial,
followed by whether the trial is recruiting patients,
- The trial may not have started and not yet recruiting, or the trial may have started and do not need any more recruitements, or the trial may be completed.
- Note**: Please follow the link to determine the current trial status.
followed by a list of drug/s, if any, used in the trial

ClinicalTrials.gov has listed the following trials for Dermatomyositis:

Myositis in Children - This study is currently recruiting patients (Current: 23 Nov 2006)
Efficacy and Safety Study of GB-0998 for Treatment of Steroid-Resistant Polymyositis and Dermatomyositis (PM/DM) - This study is currently recruiting patients (Current: 23 Nov 2006) - High-dose intravenous immunoglobulin (Venoglobulin-IH)
Study and Treatment of Inflammatory Muscle Diseases - This study is currently recruiting patients (Current: 23 Nov 2006)
Methimazole to Treat Polymyositis and Dermatomyositis - This study has been completed (Current: 23 Nov 2006)
Safety and Effectiveness of h5G1.1-mAb for Dermatomyositis - This study has been completed (Current: 23 Nov 2006) - h5G1.1-mAb
Pilot Study of Total Body Irradiation in Combination With Cyclophosphamide, Anti-Thymocyte Globulin, and Autologous CD34-Selected Peripheral Blood Stem Cell Transplantation in Children With Refractory Autoimmune Disorders - This study is currently recruiting patients (Current: 23 Nov 2006) - anti-thymocyte globulin,cyclophosphamide,filgrastim
Infliximab (Remicade (Registered Trademark)) to Treat Dermatomyositis and Polymyositis - This study is currently recruiting patients (Current: 23 Nov 2006) - Infliximab
Study of Families With Twins or Siblings Discordant for Rheumatic Disorders - This study is currently recruiting patients (Current: 23 Nov 2006)
Rituximab for the Treatment of Refractory Adult and Juvenile Dermatomyositis (DM) and Adult Polymyositis (PM) - This study is currently recruiting patients (Current: 23 Nov 2006) - Rituximab
A Pilot Study of Etanercept in Dermatomyositis - This study is currently recruiting patients (Current: 23 Nov 2006) - Etanercept
A Pilot Study of Etanercept in Dermatomyositis - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - etanercept
Understanding the Pathogenesis and Treatment of Childhood Onset Dermatomyositis - This study has been terminated (Current: 23 Nov 2006) - Prednisone,Methotrexate,Etanercept
Intravenousimmunoglobulin (IVIg) for the Treatment of Inflammatory Myopathies - This study has been completed (Current: 23 Nov 2006) - Gamma Globulin
Five-Year Actively Controlled Clinical Trial in New Onset Juvenile Dermatomyositis - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - prednisone - cyclosporine – methotrexate
Genetic and Family Studies of Inherited Muscle Diseases - This study has been completed (Current: 23 Nov 2006)
Absorption of Corticosteroids in Children With Juvenile Dermatomyositis - This study is currently recruiting patients (Current: 23 Nov 2006) - Methylprednisolone,Prednisolone
myoARRAY and TcLandscape Analysis for the Diagnosis of Inflammatory Myopathies - This study is currently recruiting patients (Current: 23 Nov 2006)
Rituximab to Treat Dermatomyositis and Polymyositis - This study is currently recruiting patients (Current: 23 Nov 2006) - Rituximab
Studies of the Natural History and Pathogenesis of Autoimmune/Connective Tissue Diseases - This study is no longer recruiting patients (Current: 23 Nov 2006)
Studies on Abnormal Bone From Patients With Polyostotic Fibrous Dysplasia and McCune Albright Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006)
Alendronate Osteoporosis Study - This study is no longer recruiting patients (Current: 23 Nov 2006) - Alendronate
Myositis in Children - This study is currently recruiting patients (Current: 23 Nov 2006)
Efficacy and Safety Study of GB-0998 for Treatment of Steroid-Resistant Polymyositis and Dermatomyositis (PM/DM) - This study is currently recruiting patients (Current: 23 Nov 2006) - High-dose intravenous immunoglobulin (Venoglobulin-IH)
Ultrasound Evaluation of Tongue Movements in Speech and Swallowing - This study has been completed (Current: 23 Nov 2006)
Study and Treatment of Inflammatory Muscle Diseases - This study is currently recruiting patients (Current: 23 Nov 2006)
Methimazole to Treat Polymyositis and Dermatomyositis - This study has been completed (Current: 23 Nov 2006)
Infliximab (Remicade (Registered Trademark)) to Treat Dermatomyositis and Polymyositis - This study is currently recruiting patients (Current: 23 Nov 2006) - Infliximab
Rituximab for the Treatment of Refractory Adult and Juvenile Dermatomyositis (DM) and Adult Polymyositis (PM) - This study is currently recruiting patients (Current: 23 Nov 2006) - Rituximab
Intravenousimmunoglobulin (IVIg) for the Treatment of Inflammatory Myopathies - This study has been completed (Current: 23 Nov 2006) - Gamma Globulin
Genetic and Family Studies of Inherited Muscle Diseases - This study has been completed (Current: 23 Nov 2006)
Prevention of Glucocorticoid-Induced Osteoporosis in Rheumatic Diseases: Alendronate Versus Alfacalcidol. - This study has been completed (Current: 23 Nov 2006) - Alendronate versus alfacalcidol (1-alpha OH vitamin D)
myoARRAY and TcLandscape Analysis for the Diagnosis of Inflammatory Myopathies - This study is currently recruiting patients (Current: 23 Nov 2006)
Rituximab to Treat Dermatomyositis and Polymyositis - This study is currently recruiting patients (Current: 23 Nov 2006) - Rituximab
Absorption of Corticosteroids in Children With Juvenile Dermatomyositis - This study is currently recruiting patients (Current: 23 Nov 2006) - Methylprednisolone,Prednisolone
Safety and Effectiveness of h5G1.1-mAb for Dermatomyositis - This study has been completed (Current: 23 Nov 2006) - h5G1.1-mAb
Pilot Study of Total Body Irradiation in Combination With Cyclophosphamide, Anti-Thymocyte Globulin, and Autologous CD34-Selected Peripheral Blood Stem Cell Transplantation in Children With Refractory Autoimmune Disorders - This study is currently recruiting patients (Current: 23 Nov 2006) - anti-thymocyte globulin,cyclophosphamide,filgrastim
Understanding the Pathogenesis and Treatment of Childhood Onset Dermatomyositis - This study has been terminated (Current: 23 Nov 2006) - Prednisone,Methotrexate,Etanercept
Study of Families With Twins or Siblings Discordant for Rheumatic Disorders - This study is currently recruiting patients (Current: 23 Nov 2006)
A Pilot Study of Etanercept in Dermatomyositis - This study is currently recruiting patients (Current: 23 Nov 2006) - Etanercept
A Pilot Study of Etanercept in Dermatomyositis - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - etanercept
Five-Year Actively Controlled Clinical Trial in New Onset Juvenile Dermatomyositis - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - prednisone - cyclosporine – methotrexate
Studies of the Natural History and Pathogenesis of Autoimmune/Connective Tissue Diseases - This study is no longer recruiting patients (Current: 23 Nov 2006)

Drugs used in Clinical Trials for Dermatomyositis

The format for each of the following is:

The drug,
followed by the name of the trial,
followed by whether the trial is recruiting patients,
- The trial may not have started and not yet recruiting, or the trial may have started and do not need any more recruitements, or the trial may be completed.
- Note**: Please follow the link to determine the current trial status.

ClinicalTrials.gov has listed the following drugs in trials for Dermatomyositis: