Maldigestion and Malabsorption Syndromes
Maldigestion and Malabsorption Syndromes: Excerpt from A Pocket Manual of Differential Diagnosis
Maldigestion Syndromes
Pancreatic disorders
Chronic pancreatitis
Pancreatic resection
Pancreatic carcinoma
Cystic fibrosis
Nonbeta islet cell tumors
Severe protein malnutrition
Effect of vagotomy on pancreatic secretion
Hepatobiliary disease
Extrahepatic biliary obstruction
Chronic intrahepatic cholestasis (e.g., primary biliary
cirrhosis)
Severe hepatocellular injury
Impaired enzyme or bile salt function owing to
Inadequate mixing (e.g., after gastric/small bowel surgery)
Low pH in small bowel (e.g., Zollinger-Ellison
syndrome)
Ileal resection
Severe diffuse ileal disease (e.g., Crohn's disease)
Malabsorption Syndromes
Mucosal disease
Celiac sprue (gluten enteropathy)
Collagenous sprue
Tropical sprue
Disaccharidase diseases and carbohydrate malabsorption
Congenital enterokinase deficiencies
Congenital glucose-galactose malabsorption
Congenital fructose malabsorption
Lactase deficiency
Sucrase-isomaltase deficiency
Trehalase deficiency
Short bowel syndrome
Massive resection
Enteroenteric fistulas
Jejunoileal bypass surgery
Gastroileal anastomosis (inadvertent)
Neoplasms
Intestinal lymphoma
Extraintestinal lymphoma
Retroperitoneal malignancy
Carcinoid syndrome
Adenocarcinoma
Extraintestinal carcinoma
Cardiovascular disorders
Congestive heart failure
Constrictive pericarditis
Chronic mesenteric vascular insufficiency
Endocrine disorders
Diabetes mellitus
Hypoparathyroidism
Hyperthyroidism
Adrenal insufficiency
Systemic disorders
Amyloidosis
Protein malnutrition
Collagen-vascular disease
Systemic lupus erythematosus
Scleroderma
Rheumatoid arthritis
Vasculitis
Polyarteritis nodosa
Dermatitis herpetiformis
Psoriasis
Kohler-Dager syndrome
Dysgammaglobulinemia, heavy-chain
Mastocytosis
Food allergy
Genetic disorders
Congenital disaccharidase deficiencies and carbohydrate malabsorption (see Disaccharidase Diseases and Carbohydrate Malabsorption section)
Abetalipoproteinemia (fat malabsorption)
Chloridorrhea, congenital or acquired
Magnesium deficiency
Vitamin D–deficient rickets
Selective vitamin B
12 malabsorption
Hartnup disease
Cystinuria (amino acid malabsorption)
Inflammation/infection
Crohn's disease
Behçet's disease
Eosinophilic gastroenteritis
Radiation enteritis
Graft-versus-host disease
Infectious enteritis
Bacterial
Bacterial overgrowth
Surgical blind loop
Stricture, fistula
Crohn's disease
Small-bowel diverticula
Hypomotility states
Intestinal diabetic neuropathy
Scleroderma
Intestinal pseudo-obstruction
Whipple's disease
Mycobacterial (
Mycobacterium tuberculosis,
M. avium complex)
Parasitic (
Giardia,
Cryptosporidia,
I. belli)
Viral (CMV, HIV)
Drugs (partial list)
Cholestyramine
Colchicine
Broad-spectrum antibiotics (e.g., neomycin)
Cytotoxic drugs
Phenindione
Methotrexate
Mefenamic acid
Alcohol
NSAIDs
Iron salts
Laxatives
Biguanides
Paraaminosalicylic acid
Other causes
Intestinal lymphangiectasia
Pernicious anemia
Iron deficiency
Protein-losing gastroenteropathy
Idiopathic steatorrhea
Paneth cell deficiency
Congenital malrotation of the intestine
Immunodeficiency
Immunoproliferative small intestinal disease
References
1. Riley SA, Marsh MN: Maldigestion and Malabsorption, pp. 1501–1522. See Bibliography, 1.
2. Kalser MH: Malabsorption Syndromes, p. 996. See Bibliography, 2.
Book Source Details
- Book Title: A Pocket Manual of Differential Diagnosis
- Author(s): Stephen N. Adler, Dianne B. Gasbarra
- Year of Publication: 1999
- Copyright Details: A Pocket Manual of Differential Diagnosis, Copyright © 1999 Lippincott Williams & Wilkins.
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