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Diseases » Diabetic hypoglycemia » Treatments
 

Treatments for Diabetic hypoglycemia

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Discussion of treatments for Diabetic hypoglycemia:

If your blood glucose is at or below 70 mg/dL, have one of these items to get 15 grams of carbohydrate:
  • 1/2 cup (4 oz.) of any fruit juice
  • 1 cup (8 oz.) of milk
  • 1 or 2 teaspoons of sugar or honey
  • 1/2 cup (4 oz.) of regular soda
  • 5 or 6 pieces of hard candy
  • glucose gel or tablets (take the amount noted on the package to add up to 15 grams of carbohydrate)

Test your blood glucose again 15 minutes later. If it is still below 70 mg/dL, then eat another 15 grams of carbohydrate. Then test your blood glucose again in 15 minutes.

If you cannot test your blood glucose right away but you feel symptoms of hypoglycemia, eat one of the items listed above.

If your blood glucose is not low, but you will not eat your next meal for at least an hour, then have a snack with starch and protein. Here are some examples:

  • crackers and peanut butter or cheese
  • half of a ham or turkey sandwich
  • a cup of milk and crackers or cereal
(Source: excerpt from Medicines for People With Diabetes: NIDDK)

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Book Excerpts: Treatment of Diabetic hypoglycemia

Treatments of Diabetic hypoglycemia: Online Medical Books

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Hypoglycemia: Treatment
(In a Page: Signs and Symptoms)

  • Glucose therapy (therapy goal is glucose >100 mg/dL)
    –Alert patients may be repleted with oral glucose (e.g., juice, glucose tablets) or IV D50
    –Patients with altered consciousness require IV D50 solution
    –In children, use bolus of 25% dextrose
    –Frequently recheck blood glucose
  • Glucagon may be used to increase glucose release from the liver if unable to obtain IV access and the patient cannot tolerate oral glucose; less effective in alcoholic and malnourished patients
  • Octreotide may be used in cases of sulfonylurea-induced hypoglycemia to inhibit insulin release
  • Thiamine must be given with glucose in any suspected case of alcohol abuse or nutritional deficiency to avoid Wernicke's encephalopathy
  • Hydrocortisone should be administered if blood glucose remains persistently low to rule out adrenal insufficiency
  • » READ BOOK EXCERPT ONLINE »

    Source: In a Page: Signs and Symptoms, 2004

    Hypoglycemia: Treatment
    (In A Page: Pediatric Signs and Symptoms)

    • If awake and alert, give glucose/feed orally
    • If impaired consciousness, D10 or D25 2-4 cc/kg IV/NG
      • For hyperinsulinism:
        –Glucagon injection acutely
        –Supranormal glucose intake chronically
        –Dietary manipulation (increased feeding frequency, some are protein sensitive)
        –Medical options: Diazoxide, octreotide
        –Surgical option: Subtotal pancreatectomy
    • For defects in fasting adaptation (including defects in glycogenolysis, gluconeogenesis, fatty acid oxidation, and ketogenesis): Frequent or continuous feeding, night-time cornstarch helpful for some
    • For hormone deficiencies: Hormone replacement (i.e., growth hormone and/or hydrocortisone)
    • Goals of therapy: Prevent recurrent hypoglycemia, prevent catabolic state, promote growth and development

    » READ BOOK EXCERPT ONLINE »

    Source: In A Page: Pediatric Signs and Symptoms, 2007

    Hypoglycemia: Treatment
    (Professional Guide to Diseases (Eighth Edition))

    Effective treatment of reactive hypoglycemia requires dietary modification to help delay glucose absorption and gastric emptying. Usually this includes small, frequent meals; ingestion of complex carbohydrates, fiber, and fat; and avoidance of simple sugars, alcohol, and fruit drinks. The patient may also receive anticholinergic drugs to slow gastric emptying and intestinal motility and to inhibit vagal stimulation of insulin release.

    For fasting hypoglycemia, surgery and drug therapy are usually required. In patients with insulinoma, tumor removal is the treatment of choice. Drug therapy may include nondiuretic thiazides such as diazoxide to inhibit insulin secretion; streptozocin; and hormones, such as glucocorticoids and long-acting glycogen.

    Therapy for neonates who have hypoglycemia or who are at risk of developing it includes preventive measures. A hypertonic solution of 10% dextrose, calculated at 5 to 10 ml/kg of body weight administered I.V. over 10 minutes and followed by 4 to 8 mg/kg/minute for maintenance, should correct a severe hypoglycemic state in neonates. To reduce the chance of hypoglycemia in high-risk neonates, they should receive feedings (either breast milk or a solution of 5% to 10% glucose and water) as soon after birth as possible.

    » READ BOOK EXCERPT ONLINE »

    Source: Professional Guide to Diseases (Eighth Edition), 2005

    Hypoglycemia: Treatment
    (Handbook of Diseases)

    Urgent treatment may be provided by glucose tablets, candy, or fluids if the patient is alert. Dextrose 50% solution is given for emergency treatment, followed by a constant infusion in children and adults. Reactive hypoglycemia and fasting hypoglycemia require different treatments.

    Reactive hypoglycemia

    Effective treatment of reactive hypoglycemia requires dietary modification to help delay glucose absorption and gastric emptying. Usually, this includes small, frequent meals; ingestion of complex carbohydrates, fiber, and fat; and avoidance of simple sugars, alcohol, and fruit drinks.

    The patient may also receive anticholinergic drugs to slow gastric emptying and intestinal motility and to inhibit vagal stimulation of insulin release.

    Fasting hypoglycemia

    In fasting hypoglycemia, surgery and drug therapy are usually required. In patients with insulinoma, removal of the tumor is the treatment of choice. Drug therapy may include nondiuretic thiazides, such as diazoxide, to inhibit insulin secretion, streptozocin, and hormones, such as glucocorticoids and long-acting glycogen.

    In neonates

    Therapy for neonates who have hypoglycemia or who are at risk of developing it includes preventive measures. A hypertonic solution of dextrose 10%, calculated at 5 to 10 ml/kg of body weight administered I.V. over 10 minutes and followed by 4 to 8 mg/kg/minute for maintenance, should correct a severe hypoglycemic state in neonates.

    To reduce the chance of hypoglycemia in high-risk neonates, they should receive feedings — either breast milk or a solution of dextrose 5% or 10% in water — as soon after birth as possible.

    » READ BOOK EXCERPT ONLINE »

    Source: Handbook of Diseases, 2003



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