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Glossary for Diabetic Ketoacidosis

  • Abdominal Pain: A condition which is characterized by the sensation of pain that is located in the abdomen
  • Acidemia, propionic: An inherited genetic disorder where the body is incapable of processing some proteins and fats resulting in the accumulation of certain substances in the body which causes the symptoms of the condition. The condition can be life threatening.
  • Acidosis: Excess acidic toxins or waste products in the blood
  • Alcohol Withdrawal: Symptoms that occur when alcohol consumption is discontinued or reduced. Symptoms may vary depending on the level of dependence.
  • Alcohol abuse: Excessive use of alcohol ranging from binge drinking to severe alcoholism
  • Alcohol use: Use of alcohol (as a symptom)
  • Appendicitis/acute appendicitis/chronic appendicitis:
  • Aspirin - Teratogenic Agent: There is strong evidence to indicate that exposure to Aspirin during pregnancy may have a teratogenic effect on the fetus. A teratogen is a substance that can cause birth defects. The likelihood and severity of defects may be affected by the level of exposure and the stage of pregnancy that the exposure occurred at.
  • Biotinidase deficiency: A metabolic disorder where the body lacks the enzyme biotinidase needed to process the vitamin called biotin (vitamin H) into carboxylase enzymes.
  • Breath odor: Unpleasant or excessive breath odor.
  • Breathing difficulties: Various types of breathing difficulty (dyspnea).
  • DEND syndrome: An inherited disorder characterized by developmental delay, epilepsy and diabetes.
  • Dehydration: Loss of fluids in the body
  • Diabetes: Failing or reduced ability of the body to handle sugars.
  • Diabetic Ketoacidosis: Life-threatening complication of high blood sugars and diabetes.
  • Ethanol - Teratogenic Agent: There is evidence to indicate that exposure to Ethanol during pregnancy may have a teratogenic effect on the fetus. A teratogen is a substance that can cause birth defects. The likelihood and severity of defects may be affected by the level of exposure and the stage of pregnancy that the exposure occurred at.
  • Forbes disease: A rare inherited glycogen storage disease caused by a deficiency of the enzyme amylo-1,6-glucosidase resulting in a build up of glycogen in the liver and muscles.
  • Glycogen storage disease type 6: A rare, generally mild form of inherited glycogen storage disease where a deficiency of phosphorylase b kinase leads to hypoglycemia and accumulation of glycogen in the liver.
  • Glycogen storage disease type 6A, due to phosphorylase kinase deficiency: A rare, generally mild form of inherited glycogen storage disease where a deficiency of phosphorylase kinase leads to hypoglycemia and accumulation of glycogen in the liver. Phosphorylase kinase deficiency can cause glycogen storage disease type VIa and/or IX.
  • Hyperglycemic Hyperosmolar Nonketotic Syndrome: Life-threatening complication of high blood sugars and diabetes.
  • Hyperkalaemia: Increased concentration of potassium in the blood.
  • Hyperphosphataemia: An increased level of phosphate in the circulation above that which is considered normal
  • Hypoglycemia: Low blood sugar level
  • Hypokalaemia: Decreased concentration of potassium in the blood
  • Hyponatraemia: Hyponatraemia means there is a lower than normal concentration of sodium in the blood.
  • Iron poisoning: Excessive ingestion of iron - often occurs when children ingest adult iron tablets.
  • Ketones in urine:
  • Lactic Acidosis: Acidic blood (acidosis) due to buildup of lactate
  • Lipoamide dehydrogenase deficiency: A very rare enzyme deficiency (dihydrolipoamide dehydrogenase) which can cause lactic acidosis. The age of onset and symptoms are variable.
  • Malonic aciduria: A very rare genetic disorder where a deficiency of a particular enzyme (malonyl-CoA decarboxylase) impairs the body's ability to convert fatty acids into energy that can be used by muscles such as the heart muscle. Fatty acids also accumulate in the body as they are not metabolized.
  • Marasmus: A form of malnutrition caused by a severe deficiency of both protein and calories
  • Nausea: The queasy feeling of nausea and often also vomiting.
  • Organic acidemia: High blood levels of organic acids which is caused by abnormal protein metabolism. Maple syrup urine disease and propionic academia are examples of organic acidemias. Deficiency of certain metabolic enzymes one of the main causes of organic academia.
  • Phenylketonuria: A metabolic disorder where there is a deficiency of the enzyme phenylalanine hydroxylase which leads to a harmful buildup of the phenylalanine in the body. Normally the phenylalanine is converted into tyrosine. The severity of the symptoms can range from severe enough to cause mental retardation to mild enough not to require treatment. Severity is determined by the level of impairment of enzyme activity of phenylalanine hydroxylase.
  • Pyruvate carboxylase deficiency, Group C: A rare inherited disorder characterized by a deficiency of pyruvate carboxylase which leads to accumulation of lactic acid and other compounds which can have a toxic effect on the nervous system and body organs. Type C is a mild form of the condition.
  • Salicylate poisoning: Excessive ingestion of salicylate drugs.
  • Type 1 diabetes: Severe insulin-treated diabetes typically occurring in young people.
  • Type 2 diabetes: Most common diabetes in adults, usually progressing slowly, mostly treated without insulin at diagnosis.
  • Uremia: Excessive urea and waste products in the blood
  • Valproic Acid - Teratogenic Agent: There is evidence to indicate that exposure to Valproic Acid during pregnancy may have a teratogenic effect on the fetus. A teratogen is a substance that can cause birth defects. The likelihood and severity of defects may be affected by the level of exposure and the stage of pregnancy that the exposure occurred at.
  • Vomiting: Vomiting or retching symptoms.


 » Next page: Clinical Trials for Diabetic Ketoacidosis

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