Cure Research for Diabetic neuropathy

Latest Treatments for Diabetic neuropathy

Some of the more recent treatments for Diabetic neuropathy include:

• Tricyclic antidepressants
• Gabapentin
• Pregabalin
• more treatments...»

Cure Research discussion for Diabetic neuropathy:

Diabetic Neuropathy The Nerve Damage of Diabetes: NIDDK (Excerpt)

Researchers are exploring treatment with a compound called myoinositol. Early findings have shown that nerves in diabetic animals and humans have less than normal amounts of this substance. Myoinositol supplements increase the levels of this substance in tissues of diabetic animals, but research is still needed to show any concrete lasting benefits from this treatment.

Another area of research concerns the drug aminoguanidine. In animals, this drug blocks cross-linking of proteins that occurs more quickly than normal in tissues exposed to high levels of glucose. Early clinical tests are under way to determine the effects of aminoguanidine in humans.

One approach that appeared promising involved the use of aldose reductase inhibitors (ARIs). ARIs are a class of drugs that block the formation of the sugar alcohol sorbitol, which is thought to damage nerves. Scientists hoped these drugs would prevent and might even repair nerve damage. But so far, clinical trials have shown that these drugs have major side effects and, consequently, they are not available for clinical use. (Source: excerpt from Diabetic Neuropathy The Nerve Damage of Diabetes: NIDDK)

Diabetes Control and Complications Trial (DCCT): NIDDK (Excerpt)

Participants in the DCCT were examined to detect the development of nerve damage (diabetic neuropathy). Study results showed the risk of nerve damage was reduced by 60 percent in persons on intensive treatment. (Source: excerpt from Diabetes Control and Complications Trial (DCCT): NIDDK)

Medical research for Diabetic neuropathy: medical news summaries:

The following medical news items are relevant to medical research for Diabetic neuropathy:

• Diabetic neuropathic pain alleviated with common nutrient
• New drug approved for treatment of pain associated with diabetic neuropathy
• More news »

Clinical Trials for Diabetic neuropathy

Some of the clinical trials for Diabetic neuropathy include:

• Tolerability of Three Local Anesthetic Formulations in Conjunction With NGX-4010 for the Treatment of Neuropathic Pain - This study is no longer recruiting patients (Current: 23 Nov 2006) - Capsaicin Dermal Patch
• An Open-Label Extension Study of NGX-4010 for the Treatment of Neuropathic Pain - This study has been terminated (Current: 23 Nov 2006) - Capsaicin Dermal Patch
• Dextromethorphan Versus Placebo for Neuropathic Pain - This study has been completed (Current: 23 Nov 2006)
• Randomized Study of Intravenous Immunoglobulin (IVIg) in Patients With Subacute Proximal Diabetic Neuropathy - This study is no longer recruiting patients (Current: 23 Nov 2006) - immune globulin
• Phase III Randomized, Double-Blind, Placebo-Controlled Study of Mexiletine for Painful Diabetic Neuropathy - This study has been completed (Current: 23 Nov 2006) - mexiletine
• more trials...»

Evidence Based Medicine Research for Diabetic neuropathy

Medical research papers related to Diabetic neuropathy include:

• Gabapentin versus tricyclic antidepressants for diabetic neuropathy and post-herpetic neuralgia: discrepancies between direct and indirect meta-analyses of randomized controlled trials
• Epalrestat: an aldose reductase inhibitor for the treatment of diabetic neuropathy
• Review: TCAs, anticonvulsants, opioids, and capsaicin cream are effective for diabetic neuropathy
• Decompressive surgery of lower limbs for symmetrical diabetic peripheral neuropathy
• Navigating the maze of drug therapy for neuropathic pain
• Vitamin B for treating peripheral neuropathy
• Assessment and management of chronic pain.
• Management of Neuropathic Pain Guidelines
• What are the reasons of bitter taste in mouth in a diabetic lady?
• Type 2 diabetes: the management of type 2 diabetes
• Control of pain in adults with cancer
• Vacuum Assisted Closure therapy
• Effects of treatments for symptoms of painful diabetic neuropathy: systematic review
• Effects of treatments for symptoms of painful diabetic neuropathy: systematic review.
• Neuropathic pain
• Skin biopsy diagnosis of peripheral neuropathy
• Antidepressants for neuropathic pain
• Lamotrigine for acute and chronic pain
• Aldose reductase inhibitors for the treatment of diabetic polyneuropathy
• Neuropathy
• A 6-Month, Randomized, Double-Masked, Placebo-Controlled Study Evaluating the Effects of the Protein Kinase Inhibitor Ruboxistaurin on Skin Microvascular Blood Flow and Other Measures of Diabetic Peripheral Neuropathy
• Is there evidence supporting the use of thiamine or benfotiamine to reduce complications in diabetics? If there is what dose would be recommended?
• Venous thromboembolism: reducing the risk of venous thromboembolism (deep vein thrombosis and pulmonary embolism) in inpatients undergoing surgery
• EFNS guidelines on neurostimulation therapy for neuropathic pain.
• Heel pain
• Pregabalin
• Is there any evidence to suggest that the use of chilli (or capsaicin supplementation) will aid blood sugar control in diabetics?
• Augmentation
• Percutaneous Electrical Stimulation (PENS)/Chronic Pain (Breast and Back)
• The hospital have issued my patient with Midodrine tablets. What is this?

Click here to find more evidence-based articles on the TRIP Database

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