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Glossary for Dilated cardiomyopathy

  • $3-methylglutaconic aciduria, type 1$: A recessively inherited metabolic disorder characterized by methylglutaconic acid in the urine.
  • $3-methylglutaconic aciduria, type V$: A rare genetic disorder where the body's cells are unable to make sufficient energy resulting in an accumulation in the body of 3-methylglutaconic acid.
  • ACAD9 deficiency: A metabolic disorder involving a deficiency of an enzyme (acyl-CoA dehydrogenase-9). The symptoms are variable and are usually triggered by a viral infection or ingestion of aspirin which can trigger a Reye-like episode which can cause death.
  • Acute Bronchitis: Respiratory inflammation of the bronchi leading to the lungs
  • Alcohol abuse: Excessive use of alcohol ranging from binge drinking to severe alcoholism
  • Atrial flutter: Heart arrhythmia where atria beat more often than ventricles
  • Barth Syndrome: A rare genetic disorder where the body's cells are unable to make sufficient energy resulting in an accumulation in the body of 3-methylglutaconic acid. Type 2 is characterized by its affects on the heart.
  • Becker Muscular Dystrophy: A muscular dystrophy charaterised by enlargement of muscles
  • Candesartan - Teratogenic Agent: There is strong evidence to indicate that exposure to Candesartan during pregnancy may have a teratogenic effect on the fetus. A teratogen is a substance that can cause birth defects. The likelihood and severity of defects may be affected by the level of exposure and the stage of pregnancy that the exposure occurred at.
  • Captopril - Teratogenic Agent: There is strong evidence to indicate that exposure to Captopril during pregnancy may have a teratogenic effect on the fetus. A teratogen is a substance that can cause birth defects. The likelihood and severity of defects may be affected by the level of exposure and the stage of pregnancy that the exposure occurred at.
  • Cardiomyopathy: Any disease of the heart muscle
  • Cardiomyopathy, dilated, with Woolly hair and keratoderma: A rare syndrome characterized by heart muscle disease involving dilation of the heart ventricles, woolly hair and thickened skin on the palms and soles.
  • Chagas disease: A parasitic infection caused by the protozoa Trypanosoma cruzi and transmitted by insect bites or blood transfusions. The disease primarily involves the heart and gastrointestinal system.
  • Childbirth: Delivery of a fetus by a pregnant woman.
  • Chromosome 1, 1p36 deletion syndrome: A rare chromosomal disorder where deletion of a portion of chromosome 1 causes various abnormalities such as heart problems, mental retardation, developmental delay, facial dysmorphism and short stature. The symptoms are variable depending on the exact location of chromosomal deletion.
  • Cough: The noise produced from the sudden expulsion of air from the lungs
  • Daunorubicin - Teratogenic Agent: There is evidence to indicate that exposure to Daunorubicin (a chemotherapy drug) during pregnancy may have a teratogenic effect on the fetus. A teratogen is a substance that can cause birth defects. The likelihood and severity of defects may be affected by the level of exposure and the stage of pregnancy that the exposure occurred at.
  • Desmin related myopathy: A very rare neuromuscular disorder involving the buildup of a certain protein called desmin in various muscles. The severity and rate of progression of the disorder is variable.
  • Dilated cardiomyopathy: A rare chronic heart muscle condition where one or both heart ventricles are dilated or have impaired contractility.
  • Doxorubicin - Teratogenic Agent: There is evidence to indicate that exposure to Doxorubicin (a chemotherapy drug) during pregnancy may have a teratogenic effect on the fetus. A teratogen is a substance that can cause birth defects. The likelihood and severity of defects may be affected by the level of exposure and the stage of pregnancy that the exposure occurred at.
  • Duchenne Muscular Dystrophy: An inherited degenerative disease of the muscles which progresses rapidly compared to other muscle wasting diseases.
  • Embolism: Blockage of an artery or blood vessel
  • Emery-Dreifuss muscular dystrophy, X-linked: A muscle wasting disorder mainly involving the muscles in the arms, legs, face, neck, spine and heart. Symptoms generally only occur in males but female carriers may have some symptoms.
  • Endocardial fibroelastosis: A rare heart disorder characterized by a thickening of the heart muscle lining causing heart enlargement and heart failure.
  • Enteroviruses: Viruses affecting the digestive tract.
  • Fabry's Disease: Genetic fat storage disorder
  • Fatigue: Excessive tiredness or weakness.
  • Heart conditions: Any condition that affects the heart
  • Heart disease: Any of various heart conditions.
  • Heart failure: Slow failure of the heart (cardiac insufficiency).
  • Hemochromatosis: Excess of iron leading to problems with joints, liver, heart and pancreas.
  • Hyperthyroidism: Too much thyroid hormone production.
  • Idiopathic, hypertrophic, subaortic stenosis: A rare heart disorder where thickening of parts of the heart (wall separating the heart chambers) reduces the size of heart chambers and hinders the flow of blood.
  • Irregular heartbeat: An irregular beat of a persons heart
  • Limb-girdle muscular dystrophy type 1D: An autosomal dominant form of limb-girdle muscular dystrophy where muscle weakness and atrophy is caused by mutations of chromosome 6. Males are more severely affected than females in this form of the disease.
  • Mc Leod neuroacanthocytosis syndrome: A rare syndrome characterized by neuromuscular, blood and central nervous system symptoms. The disease is slowly progressive.
  • Monosomy 1p36: A rare chromosomal disorder where deletion of a portion of chromosome 1 causes various abnormalities such as heart problems, mental retardation, developmental delay, facial dysmorphism and short stature. The range and severity of symptoms is variable with some cases being relatively mild.
  • Muscular dystrophy, Duchenne and Becker type: An inherited l disorder characterized by progressive muscle weakness. The disorder is caused by a genetic anomaly and results in insufficient quantities of or ineffective dystrophin which is needed for normal muscle functioning. The disorder is expressed in males but females can be carriers.
  • Myocarditis: Inflammation of the myocardium (muscle walls of the heart)
  • Myopathy, early-onset with fatal cardiomyopathy: A rare disorder involving muscle disease and early onset heart disease which leads to death.
  • Naxos disease: A very rare syndrome characterized mainly by heart disease and woolly hair.
  • No symptoms: The absence of noticable symptoms.
  • Pericardial effusion: Occurs when there is an abnormal collection of fluid within the pericardial sac
  • Pneumonia: Infection of the lung by bacteria, viruses or fungus.
  • Pregnancy: The condition of supporting a fetus from conception till birth.
  • Restrictive cardiomyopathy: A condition which is characterized by restriction to the function of the walls of the heart
  • Shortness of breath: The feeling of being short of breath
  • Sudden death: The sudden death of an individual
  • Weakness: Symptoms causing weakness of the body
  • Woolly hair - palmoplantar keratoderma - dilated cardiomyopathy: A rare syndrome characterized by heart muscle disease involving dilation of the heart ventricles, woolly hair and thickened skin on the palms and soles.


 » Next page: Clinical Trials for Dilated cardiomyopathy

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