Diagnosis of Diphtheria
Diphtheria Diagnosis: Book Excerpts
Diagnostic Tests for Diphtheria: Online Medical Books
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Diphtheria:
Diagnosis
(Professional Guide to Diseases (Eighth Edition))
CONFIRMING DIAGNOSIS Examination showing the characteristic membrane and a throat culture, or culture of other suspect lesions growing C. diphtheriae, confirm this diagnosis.
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Source: Professional Guide to Diseases (Eighth Edition), 2005
Diphtheria:
Diphtheria - DIAGNOSIS
(The 5-Minute Pediatric Consult)
- Respiratory tract diphtheria:
- Nasal diphtheria starts with mild rhinorrhea that gradually becomes serosanguineous, then mucopurulent and often malodorous; occurs most often in infants.
- Tonsillar and pharyngeal diphtheria begin with anorexia, malaise, low-grade fever, and pharyngitis. A membrane appears within 1–2 days. Cervical lymphadenitis and edema of the cervical soft tissues may be severe. Disease course varies with extent of toxin elaboration and membrane production. Respiratory and cardiovascular collapse may occur.
- Laryngeal diphtheria most often represents extension of a pharyngeal infection and clinically presents as typical croup. Acute airway obstruction may occur, and in severe cases, the membrane may invade the entire tracheobronchial tree.
- Cutaneous diphtheria occurs in warmer tropical regions. It is characterized by chronic nonhealing ulcers with gray membrane and may serve as a reservoir in endemic and epidemic areas of respiratory diphtheria.
- Other sites: Rarely vulvovaginal, conjunctival, or aural forms occur.
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Source: The 5-Minute Pediatric Consult, 2008
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