Clinical Trials for Duodenal conditions

Clinical trials are research studies conducted in an effort to improve overall patient health and care. Each trial involves running supervised tests to determine the effectiveness and safety of new drugs, procedures and/or devices with the aim of answering scientific questions about a disease or condition. Risks and side-effects are also evaluated during these trials with results ranging from being unpleasant, with side effects such as headaches, to more serious or even life-threatening risks. A clinical trial may be separated into phases, or steps, with each step designed to answer a separate research question. This maybe reflected in the trial name.

A brief description of each phase:

• Phase I: Usually designed to evaluate safety, determine a safe dosage range, and identify side effects on a small group of patients.
• Phase II: If Phase I is successful, the trial is then repeated with a larger group to further evaluate its effect and safety.
• Phase III: Trials are conducted on an ever larger group and are compared with the best current treatment while gathering more information on effect and safety.
• Phase IV: These studies monitor long-term side effects after the treatment has been marketed.

Clinical Trials data for Duodenal conditions is grouped into the following categories:-

• View by trial name
• View by drugs used in Duodenal conditions clinical trials

Clinical Trials by trial name

The format for each of the following is:

• The name of the trial,
• followed by whether the trial is recruiting patients,
  - The trial may not have started and not yet recruiting, or the trial may have started and do not need any more recruitements, or the trial may be completed.
  - Note**: Please follow the link to determine the current trial status.
• followed by a list of drug/s, if any, used in the trial

ClinicalTrials.gov has listed the following trials for Duodenal conditions:

• Helicobacter Pylori Eradication With a New Sequential Treatment - This study has been completed (Current: 23 Nov 2006) - Sequential therapy
• Celebrex Low Dose ASA Study Examining the Incidence of Gastroduodenal Ulcers in a Healthy Population - This study has been completed (Current: 23 Nov 2006) - Celecoxib,Naproxen,ASA
• Tailored Treatment of H. Pylori Infection Based Polymorphisms of CYP2C19 and 23S rRNA of H. Pylori - This study is currently recruiting patients (Current: 23 Nov 2006) - Lansoprazole,clarithromycin,amoxicillin
• Study to Assess the Efficacy and Safety of Somatostatin in the Treatment of Acute Severe Upper Gastrointestinal Bleeding - This study is no longer recruiting patients (Current: 23 Nov 2006) - Somatostatin UCB (drug)
• Study of the Natural History of Non-NSAID, Non-HP Bleeding Peptic Ulcers - This study is currently recruiting patients (Current: 23 Nov 2006)
• On-Demand Use of Pantoprazole: Determinants for Chronic Use of Acid Suppressive Medication - This study is no longer recruiting patients (Current: 23 Nov 2006) - pantoprazole 20 mg (drug)
• Administration of High-Dose Intravenous Proton Pump Inhibitor for Upper Gastrointestinal Bleeding Prior to Endoscopy - This study has been completed (Current: 23 Nov 2006) - Omeprazole
• Lymphocytic Subsets and Cytokine Production With H. Pylori Infection - This study has been completed (Current: 23 Nov 2006)
• A Study to Test Two Treatments for Safety and Prevention of Stomach Side Effects in Subjects With Osteoarthritis Taking Low Dose Aspirin. - This study has been completed (Current: 23 Nov 2006) - Lansoprazole,naproxen,celecoxib
• Study of Irinotecan Administered as a Continuous Infusion and Radiation Therapy for Upper Gastrointestinal Cancers - This study is currently recruiting patients (Current: 23 Nov 2006) - irinotecan
• Second Line Therapy for the Cure of Helicobacter Pylori (H. Pylori) Infection - This study is currently recruiting patients (Current: 23 Nov 2006) - rabeprazole,amoxicillin,clarithromycin,metronidazole
• Cytokine Gene Polymorphisms in Gastric Diseases - This study is currently recruiting patients (Current: 23 Nov 2006)
• NEXIUM in the Treatment of Moderate and Severe Erosive Esophagitis - This study is no longer recruiting patients (Current: 23 Nov 2006) - esomeprazole magnesium (oral medication)
• Risk Factors for Gastric Disease in Pediatric Helicobacter Pylori (H. Pylori) - This study is currently recruiting patients (Current: 23 Nov 2006)
• Esomeprazole for Treatment of GERD in Pediatric Patients - This study is no longer recruiting patients (Current: 23 Nov 2006) - Esomeprazole
• Comparison of Intravenous Omeprazole to Ranitidine on Recurrent Bleeding After Endoscopic Treatment of Bleeding Ulcer. - This study is currently recruiting patients (Current: 23 Nov 2006) - Omeprazole (20 mg), intravenous, 2x /day,Ranitidine (100 mg), intravenous drip infusion, 2x /day
• A Study to Compare the Efficacy and Safety of TAK-390MR and Lansoprazole on Healing of Erosive Esophagitis - This study is currently recruiting patients (Current: 23 Nov 2006) - Tak-390MR oral / Lansoprazole oral
• A Study to Compare the Efficacy and Safety of TAK-390MR and Lansoprazole on Healing of Erosive Esophagitis - This study is currently recruiting patients (Current: 23 Nov 2006) - TAK-390MR oral / Lansoprazole oral
• A Study to Compare the Efficacy and Safety of TAK-390MR and Placebo on the Ability to Maintain Healing in Subjects With Healed Erosive Esophagitis - This study is no longer recruiting patients (Current: 23 Nov 2006) - TAK-390MR oral
• A Study to Compare the Efficacy and Safety of TAK-390MR and Placebo on the Ability to Maintain Healing in Subjects With Healed Erosive Esophagitis - This study is no longer recruiting patients (Current: 23 Nov 2006) - TAK-390MR oral
• Long-Term Pantoprazole Trial in Patients With Symptoms of Chronic Acid Peptic Complaints (BY1023/VMG-708) - This study is no longer recruiting patients (Current: 23 Nov 2006) - Pantoprazole
• Dose-Effect of S-Tenatoprazole-Na(STU-Na) 30 mg, 60 mg, 90 mg and 120 mg in Healthy Volunteers - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - S-Tenatoprazole-Na (STU-Na)
• AGN 201904 Versus Esomeprazole in the Prevention of Aspirin-Induced Stomach or Upper Intestinal Damage in Healthy Volunteers - This study is currently recruiting patients (Current: 23 Nov 2006) - AGN 201904
• A Randomized Trial of Two Surgical Techniques for Pancreaticojejunostomy in Patients Undergoing Pancreaticoduodenectomy - This study is currently recruiting patients (Current: 23 Nov 2006)
• High Versus Standard Dose of Proton Pump Inhibitors (PPIs) in Peptic Ulcer Bleeding - This study is currently recruiting patients (Current: 23 Nov 2006) - omeprazole

Drugs used in Clinical Trials for Duodenal conditions

The format for each of the following is:

• The drug,
• followed by the name of the trial,
• followed by whether the trial is recruiting patients,
  - The trial may not have started and not yet recruiting, or the trial may have started and do not need any more recruitements, or the trial may be completed.
  - Note**: Please follow the link to determine the current trial status.

ClinicalTrials.gov has listed the following drugs in trials for Duodenal conditions:

• AGN 201904 - AGN 201904 Versus Esomeprazole in the Prevention of Aspirin-Induced Stomach or Upper Intestinal Damage in Healthy Volunteers - This study is currently recruiting patients (Current: 23 Nov 2006)
• ASA - Celebrex Low Dose ASA Study Examining the Incidence of Gastroduodenal Ulcers in a Healthy Population - This study has been completed (Current: 23 Nov 2006)
• Amoxicillin - Second Line Therapy for the Cure of Helicobacter Pylori (H. Pylori) Infection - This study is currently recruiting patients (Current: 23 Nov 2006)
• Amoxicillin - Tailored Treatment of H. Pylori Infection Based Polymorphisms of CYP2C19 and 23S rRNA of H. Pylori - This study is currently recruiting patients (Current: 23 Nov 2006)
• Celecoxib - A Study to Test Two Treatments for Safety and Prevention of Stomach Side Effects in Subjects With Osteoarthritis Taking Low Dose Aspirin. - This study has been completed (Current: 23 Nov 2006)
• Celecoxib - Celebrex Low Dose ASA Study Examining the Incidence of Gastroduodenal Ulcers in a Healthy Population - This study has been completed (Current: 23 Nov 2006)
• Clarithromycin - Second Line Therapy for the Cure of Helicobacter Pylori (H. Pylori) Infection - This study is currently recruiting patients (Current: 23 Nov 2006)
• Clarithromycin - Tailored Treatment of H. Pylori Infection Based Polymorphisms of CYP2C19 and 23S rRNA of H. Pylori - This study is currently recruiting patients (Current: 23 Nov 2006)
• Esomeprazole Magnesium (Oral Medication) - NEXIUM in the Treatment of Moderate and Severe Erosive Esophagitis - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Esomeprazole - Esomeprazole for Treatment of GERD in Pediatric Patients - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Irinotecan - Study of Irinotecan Administered as a Continuous Infusion and Radiation Therapy for Upper Gastrointestinal Cancers - This study is currently recruiting patients (Current: 23 Nov 2006)
• Lansoprazole - A Study to Test Two Treatments for Safety and Prevention of Stomach Side Effects in Subjects With Osteoarthritis Taking Low Dose Aspirin. - This study has been completed (Current: 23 Nov 2006)
• Lansoprazole - Tailored Treatment of H. Pylori Infection Based Polymorphisms of CYP2C19 and 23S rRNA of H. Pylori - This study is currently recruiting patients (Current: 23 Nov 2006)
• Metronidazole - Second Line Therapy for the Cure of Helicobacter Pylori (H. Pylori) Infection - This study is currently recruiting patients (Current: 23 Nov 2006)
• Naproxen - A Study to Test Two Treatments for Safety and Prevention of Stomach Side Effects in Subjects With Osteoarthritis Taking Low Dose Aspirin. - This study has been completed (Current: 23 Nov 2006)
• Naproxen - Celebrex Low Dose ASA Study Examining the Incidence of Gastroduodenal Ulcers in a Healthy Population - This study has been completed (Current: 23 Nov 2006)
• Omeprazole (20 mg), intravenous, 2x /day - Comparison of Intravenous Omeprazole to Ranitidine on Recurrent Bleeding After Endoscopic Treatment of Bleeding Ulcer. - This study is currently recruiting patients (Current: 23 Nov 2006)
• Omeprazole - Administration of High-Dose Intravenous Proton Pump Inhibitor for Upper Gastrointestinal Bleeding Prior to Endoscopy - This study has been completed (Current: 23 Nov 2006)
• Omeprazole - High Versus Standard Dose of Proton Pump Inhibitors (PPIs) in Peptic Ulcer Bleeding - This study is currently recruiting patients (Current: 23 Nov 2006)
• Pantoprazole 20 Mg (Drug) - On-Demand Use of Pantoprazole: Determinants for Chronic Use of Acid Suppressive Medication - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Pantoprazole - Long-Term Pantoprazole Trial in Patients With Symptoms of Chronic Acid Peptic Complaints (BY1023/VMG-708) - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Rabeprazole - Second Line Therapy for the Cure of Helicobacter Pylori (H. Pylori) Infection - This study is currently recruiting patients (Current: 23 Nov 2006)
• Ranitidine (100 mg), intravenous drip infusion, 2x /day. - Comparison of Intravenous Omeprazole to Ranitidine on Recurrent Bleeding After Endoscopic Treatment of Bleeding Ulcer. - This study is currently recruiting patients (Current: 23 Nov 2006)
• S-Tenatoprazole-Na (STU-Na) - Dose-Effect of S-Tenatoprazole-Na(STU-Na) 30 mg, 60 mg, 90 mg and 120 mg in Healthy Volunteers - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Sequential therapy - Helicobacter Pylori Eradication With a New Sequential Treatment - This study has been completed (Current: 23 Nov 2006)
• Somatostatin UCB (drug) - Study to Assess the Efficacy and Safety of Somatostatin in the Treatment of Acute Severe Upper Gastrointestinal Bleeding - This study is no longer recruiting patients (Current: 23 Nov 2006)
• TAK-390MR oral / Lansoprazole oral - A Study to Compare the Efficacy and Safety of TAK-390MR and Lansoprazole on Healing of Erosive Esophagitis - This study is currently recruiting patients (Current: 23 Nov 2006)
• TAK-390MR oral - A Study to Compare the Efficacy and Safety of TAK-390MR and Placebo on the Ability to Maintain Healing in Subjects With Healed Erosive Esophagitis - This study is no longer recruiting patients (Current: 23 Nov 2006)
• TAK-390MR oral - A Study to Compare the Efficacy and Safety of TAK-390MR and Placebo on the Ability to Maintain Healing in Subjects With Healed Erosive Esophagitis - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Tak-390MR oral / Lansoprazole oral - A Study to Compare the Efficacy and Safety of TAK-390MR and Lansoprazole on Healing of Erosive Esophagitis - This study is currently recruiting patients (Current: 23 Nov 2006)

The trial data on this page has been sourced from

• The U.S. National Library of Medicine (NLM) together with ClinicalTrials.gov

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