Dupuytren's contracture

Introduction: Dupuytren's contracture

Dupuytren's contracture: A condition where the layer of connective tissue under the skin of the palm of the hand thickens and shrinks which can cause the fingers to bend in to the palms. The bent fingers are usually unable to be fully straightened. More detailed information about the symptoms, causes, and treatments of Dupuytren's contracture is available below.

Symptoms of Dupuytren's contracture

• Hand contracture
• One or both hands affected
• Gradually progression hand contracture
• Nodular thickening of palms
• Dimpling of skin on palms

See full list of 9 symptoms of Dupuytren's contracture

Medical Textbooks Online about Dupuytren's contracture

Book excerpts: Copyright © 2008 Lippincott Williams & Wilkins. All rights reserved.

Wrongly Diagnosed with Dupuytren's contracture?

• Misdiagnosis of Dupuytren's contracture
• Underlying causes of Dupuytren's contracture (possibly wrongly diagnosed)

Causes of Dupuytren's contracture

Read more about causes of Dupuytren's contracture.

More information about causes of Dupuytren's contracture:

• Dupuytren's contracture as a complication caused by other conditions
• Dupuytren's contracture as a symptom

Treatments for Dupuytren's contracture

• Watchful waiting
• Surgery

Read more about treatments for Dupuytren's contracture

Videos for Dupuytren's contracture

Patient Surveys for Dupuytren's contracture

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Reseach about Dupuytren's contracture

Visit our research pages for current research about Dupuytren's contracture treatments.

Clinical Trials for Dupuytren's contracture

The US based website ClinicalTrials.gov lists information on both federally and privately supported clinical trials using human volunteers.

Some of the clinical trials listed on ClinicalTrials.gov for Dupuytren's contracture include:

• Phase II Randomized Study of Collagenase in Patients With Residual Type Dupuytren's Disease - This study is currently recruiting patients (Current: 23 Nov 2006) - collagenase
• Phase III Randomized Study of Collagenase in Patients With Residual Stage Dupuytren's Disease - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - collagenase
• Collagenase in the Treatment of Dupuytrens Disease - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - Collagenase

Read more about Clinical Trials for Dupuytren's contracture

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User Interactive Forums

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Definitions of Dupuytren's contracture:

A fibromatosis of the palmar fascia characterized by thickening and contracture of the fibrous bands on the palmar surfaces of the hand and fingers. It arises most commonly in men between the ages of 30 and 50. - (Source - Diseases Database)

Dupuytren's contracture is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH). This means that Dupuytren's contracture, or a subtype of Dupuytren's contracture, affects less than 200,000 people in the US population.
Source - National Institutes of Health (NIH)