Fever of Unknown Origin in the United States*
Fever of Unknown Origin in the United States*: Excerpt from A Pocket Manual of Differential Diagnosis
Infection
Bacterial
Bacterial endocarditis
Sinusitis
Osteomyelitis
Intravascular catheter infections
Bronchiectasis
Relapsing mastoiditis
Upper abdominal sources
Cholangitis
Cholecystitis
Empyema of the gallbladder
Subphrenic, pancreatic, hepatic, and splenic abscesses
Lower abdominal sources
Appendicitis
Appendiceal abscess
Diverticulitis
Pelvic inflammatory disease or abscess
Perirectal abscess
Peritonitis
Septic pelvic thrombophlebitis
Genitourinary sources
Perinephric, intrarenal abscess
Prostatic abscess
Pyelonephritis
Ureteral obstruction
Renal tuberculosis
Acute rheumatic fever
Bacteremia without primary focus, especially
Meningococcemia
Gonococcemia
Salmonellosis
Listeriosis
Brucellosis
Ehrlichiosis
Borreliosis
Yersiniosis
Tularemia
Leptospirosis
Tuberculosis (TB), especially
Mycobacterium tuberculosis,
Mycobacterium avium complex,
Mycobacterium kansasii
Viral, especially Epstein-Barr virus (EBV) (infectious mononucleosis), hepatitis, coxsackie B, cytomegalovirus (CMV), human immunodeficiency virus (HIV), parvovirus B19, dengue
Chlamydial, rickettsial (especially Q fever, psittacosis)
Parasitic, protozoan, especially
Amebiasis
Malaria
Trichinosis
Toxoplasmosis
Pneumocystis carinii
Babesiosis
Fungal, especially
Histoplasmosis
Blastomycosis
Cryptococcosis
Coccidiomycosis
Sporotrichosis
Malignancy
Leukemia, lymphoma, especially Hodgkin's disease
Solid tumor, especially carcinoma of
Kidney
Lung
Pancreas
Liver
Colon
Metastatic carcinoma
Carcinomatosis
Atrial myxoma
Collagen-Vascular Disease
Systemic lupus erythematosus
Rheumatoid arthritis
Rheumatic fever
Polyarteritis nodosa, hypersensitivity vasculitis
Wegener's granulomatosis
Temporal arteritis
Adult Still's disease
Cryoglobulinemia
Churg-Strauss vasculitis
Takayasu's arteritis
Drugs
Antibiotics, especially
Penicillins
Cephalosporins
Sulfonamides
Amphotericin B
Quinolones
TB therapy, especially isoniazid (INH)
Allopurinol
Phenytoin
Barbiturates
Procainamide
Quinidine
Nonsteroidal antiinflammatory therapy
Antineoplastic therapy
Interferon
H
2 blockers
Methyldopa
Other
Pulmonary emboli, multiple
Thrombophlebitis
Sarcoidosis
Hepatitis (alcoholic or granulomatous)
Inflammatory bowel disease
Whipple's disease
Thyroiditis
Thyrotoxicosis
Myelofibrosis
Serum sickness
Hemolytic states
Trauma with hematoma in closed spaces (especially peri-
splenic, perihepatic, perivesicular)
Dissecting aneurysm
Periodic fever (especially familial Mediterranean fever)
Gout
Addison's disease
Adrenal insufficiency
Weber-Christian disease
Cyclic neutropenia
Cat scratch fever
Kikuchi disease
Postpericardotomy syndrome
Factitious fever
Habitual hyperthermia
References
1. Petersdorf RG, Beeson PB: Fever of Unexplained Origin: Report on 100 Cases.
Medicine (Baltimore) 40:1, 1961.
2. Petersdorf RG: Fever of Unknown Origin: an Old Friend Revisited (Editorial).
Arch Intern Med 152:21, 1992.
3. See Bibliography, 1.
4. See Bibliography, 2.
5. See Bibliography, 3.
6. See Bibliography, 8.
*Defined as temperature of >38.3°C daily for 2 to 3 weeks, with cause undiagnosed despite 1 week of intensive studies in hospital.
References
1. Hoeprich, pp. 133–140, 838–840, 936–940, 956–960. See Bibliography, 1.
2. Kelley, pp. 1570–1575, 1584–1585, 1764–1767, 1812–1819, 1968–1973. See Bibliography, 2.
3. Schlossberg, pp. 261–278. See Bibliography, 3.
4. Mandell, pp. 2666–2686, 2709–2715, 2717–2732. See Bibliography, 8.
Book Source Details
- Book Title: A Pocket Manual of Differential Diagnosis
- Author(s): Stephen N. Adler, Dianne B. Gasbarra
- Year of Publication: 1999
- Copyright Details: A Pocket Manual of Differential Diagnosis, Copyright © 1999 Lippincott Williams & Wilkins.
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Copyright notice for book excerpts: Copyright © 2008 Lippincott Williams & Wilkins. All rights reserved.
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