1 per 5,000 - 6,000 newborns are affected by Trisomy 18, Genetics Home Reference website ... see also overview of Edwards Syndrome.
approx 1 in 5,000 or 0.02% or 54,400 people in USA [Source statistic for calcuation: "1 per 5,000 - 6,000 newborns are affected by Trisomy 18, Genetics Home Reference website" -- see also general information about data sources]
Edwards Syndrome is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH). This means that Edwards Syndrome, or a subtype of Edwards Syndrome, affects less than 200,000 people in the US population.
Ophanet, who are a consortium of European partners, currently defines a condition rare when if affects 1 person per 2,000. They list Edwards Syndrome as a "rare disease". More information about Edwards Syndrome is available from Orphanet
1-in-3000 approximately. ... see also overview of Edwards Syndrome.
approx 1 in 3,000 or 0.03% or 90,666 people in USA [Source statistic for calcuation: "1-in-3000 approximately." -- see also general information about data sources]
90,666 per year, 7,555 per month, 1,743 per week, 248 per day, 10 per hour, 0 per minute, 0 per second. [Source statistic for calculation: "1-in-3000 approximately." -- see also general information about data sources]
The following statistics relate to the incidence of Edwards Syndrome:
16 MEDICAL BOOKS ONLINE! Review excerpts from medical books online, free, without registration, for more information about the prevalence and/or incidence of Edwards Syndrome.
Most cases of trisomy 18 syndrome are caused by spontaneous meiotic nondisjunction. The risk of chromosomal abnormalities typically increases with maternal age; however, the mean maternal age for this disorder is 32½. Incidence is 1 in 3,000 neonates, with females three times more likely to be affected than males.
Source: Professional Guide to Diseases (Eighth Edition), 2005
Approximately 75% of all cases of trisomy 13 syndrome are caused by chromosomal nondisjunction. About 20% are due to chromosomal translocation involving a rearrangement of chromosomes 13 and 14. About 5% are estimated to be mosaics; the clinical effects in these cases may be less severe.
Incidence is estimated to be 1 in every 5,000 neonates. The risk of chromosomal abnormalities typically increases with advanced maternal age; however, the mean maternal age for this abnormality is about 31 years.
Source: Professional Guide to Diseases (Eighth Edition), 2005
1/600–1/800 live births, although incidence varies with maternal age:
Source: The 5-Minute Pediatric Consult, 2008
The term 'prevalence' of Edwards Syndrome usually refers to the estimated population of people who are managing Edwards Syndrome at any given time. The term 'incidence' of Edwards Syndrome refers to the annual diagnosis rate, or the number of new cases of Edwards Syndrome diagnosed each year. Hence, these two statistics types can differ: a short-lived disease like flu can have high annual incidence but low prevalence, but a life-long disease like diabetes has a low annual incidence but high prevalence. For more information see about prevalence and incidence statistics.
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