Endodermal sinus tumor: A form of malignant germ cell tumor that occurs mainly in young children. They can occur in the testis, ovaries, uterus, abdomen, thorax, tailbone region, vagina, liver, retroperitoneum and pineal ventricle of the brain. Symptoms will vary depending on the exact location of the tumor. More detailed information about the symptoms, causes, and treatments of Endodermal sinus tumor is available below.
See full list of 29 symptoms of Endodermal sinus tumor
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Prognosis for Endodermal sinus tumor: patients usually respond well to combination therapy
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The US based website ClinicalTrials.gov lists information on both federally and privately supported clinical trials using human volunteers.
Some of the clinical trials listed on ClinicalTrials.gov for Endodermal sinus tumor include:
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This is the most common malignant germ cell tumor in the pediatric population. Yolk sac tumors arise in the infant testis, ovary, sacrococcygeal region, vagina, uterus, prostate, abdomen, liver, retroperitoneum, thorax and pineal/third ventricle. The tumor mimics the yolk sac of the embryo and produces alpha-fetoprotein (AFP). Treatment includes: surgical resection, radiation and chemotherapy. This tumor is very responsive to chemotherapy regimens that include cisplatinum. - 2002 - (Source - Diseases Database)
Ophanet, a consortium of European partners,
currently defines a condition rare when it affects 1 person per 2,000.
They list Endodermal sinus tumor as a "rare disease".
Source - Orphanet
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