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Erythema

Erythema: Excerpt from Alarming Signs and Symptoms: Lippincott Manual of Nursing Practice Series

Dilated or congested blood vessels produce red skin, or erythema, the most common sign of skin inflammation or irritation. Erythema may be localized or generalized and may occur suddenly or gradually. Skin color can range from bright red in patients with acute conditions to pale violet or brown in those with chronic problems. Erythema must be differentiated from purpura, which causes redness from bleeding into the skin. When pressure is applied directly to the skin, erythema blanches momentarily, but purpura doesn’t.

Erythema usually results from changes in the arteries, veins, and small vessels that lead to increased small-vessel perfusion. Drugs and neurogenic mechanisms can allow extra blood to enter the small vessels. Erythema can also result from trauma and tissue damage and increased visibility of vessels due to changes in supporting tissues.

Act Now: If your patient has sudden progressive erythema with rapid pulse, dyspnea, hoarseness, and agitation, quickly take his vital signs. These may be indications of anaphylactic shock. Provide emergency respiratory support and give epinephrine.

Assessment

History

If erythema isn’t associated with anaphylaxis, obtain a detailed health history. Find out how long the patient has had the erythema and where it first began. Has he had any associated pain or itching? Has he recently had a fever, upper respiratory tract infection, or joint pain? Does he have a history of skin disease or other illness? Does he or anyone in his family have allergies, asthma, or eczema? Find out if he has been exposed to someone who has had a similar rash or who is now ill. Did he have a recent fall or injury in the area of the erythema?

Obtain a complete drug history, including recent immunizations. Ask about food intake and exposure to chemicals.

Physical examination

Begin the physical examination by assessing the extent, distribution, and intensity of erythema. Look for edema and other skin lesions, such as hives, scales, papules, and purpura. Examine the affected area for warmth, and gently palpate it to check for tenderness or crepitus.

Pediatric pointers

Normally, newborn rash (erythema toxicum neonatorum), a pink papular rash, develops during the first 4 days after birth and spontaneously disappears by the 10th day. Neonates and infants can also develop erythema from infections and other disorders. For instance, candidiasis can produce thick white lesions over an erythematous base on the oral mucosa as well as diaper rash with beefy red erythema.

Roseola, rubeola, scarlet fever, granuloma annulare, and cutis marmorata also cause erythema in children.

Geriatric pointers

Elderly patients commonly have well-demarcated purple macules or patches, usually on the back of the hands and on the forearms. Known as actinic purpura, this condition results from blood leaking through fragile capillaries. The lesions disappear spontaneously.

Medical causes

Allergic reactions

Foods, drugs, chemicals, and other allergens can cause an allergic reaction and erythema. A localized allergic reaction also produces hivelike eruptions and edema.

Anaphylaxis, a life-threatening condition, produces relatively sudden erythema in the form of urticaria. It also produces flushing; facial edema; diaphoresis; weakness; sneezing; bronchospasm with dyspnea and tachypnea; shock with hypotension and cool, clammy skin; and possibly airway edema with hoarseness and stridor.

Burns

With thermal burns, erythema and swelling appear first, possibly followed by deep or superficial blisters and other signs of damage that vary with the severity of the burn. Burns from ultraviolet rays, such as sunburn, cause delayed erythema and tenderness on exposed areas of the skin.

Candidiasis

When candidiasis — a fungal infection — affects the skin, it produces erythema and a scaly, papular rash under the breasts and at the axillae, neck, umbilicus, and groin, also known as intertrigo. Small pustules commonly occur at the periphery of the rash (satellite pustulosis).

Cellulitis

Erythema, tenderness, and edema are a result of a bacterial infection of the skin (most commonly streptococcal and staphylococcal) and subcutaneous tissue.

Dermatitis

Erythema commonly occurs in this family of inflammatory disorders. With atopic dermatitis, erythema and intense pruritus precede the development of small papules that may redden, weep, scale, and lichenify. These occur most commonly at skin folds of the extremities, neck, and eyelids.

Contact dermatitis occurs after exposure to an irritant. It quickly produces inflammation, erythema and vesicles, blisters, or ulcerations on exposed skin.

With seborrheic dermatitis, erythema appears with dull red or yellow lesions. Sharply marginated, these lesions are sometimes ring shaped and covered with greasy scales. They usually occur on the scalp, eyebrows, ears, and nasolabial folds, but they may form a butterfly rash on the face or move to the chest or to skin folds on the trunk. This disorder is common in patients infected with the human immunodeficiency virus and in infants (cradle cap).

Dermatomyositis

Dermatomyositis, most common in females older than age 50, produces a dusky lilac rash on the face, neck, upper torso, and nail beds. Other symptoms include fever, malaise, and weakness. Gottron’s papules (violet, flat-topped lesions) may appear on finger joints.

Erythema annulare centrifugum

Small, pink, ring-shaped infiltrated papules appear on the trunk, buttocks, and inner thighs, slowly spreading at the margins and clearing in the center. Itching, scaling, and tissue hardening may occur.

Erythema marginatum rheumaticum

Associated with rheumatic fever, erythema marginatum rheumaticum causes erythematous lesions that are superficial, flat, and slightly hardened. They shift, spread rapidly, and may last for hours or days, recurring after a time.

Erythema multiforme

Erythema multiforme is an acute inflammatory skin disease that develops as a result of drug sensitivity after infection, most commonly herpes simplex and Mycoplasma; allergies; and pregnancy. One-half of the cases are of idiopathic origin.

Erythema multiforme minor has typical urticarial, red-pink, iris-shaped, localized lesions with little or no mucous membrane involvement. Most lesions occur on flexor surfaces of the extremities. Burning or itching may occur before or in conjunction with lesion development. Lesions appear in crops and last 2 to 3 weeks. After 1 week individual lesions become flat or hyperpigmented. Early signs and symptoms may include a mild fever, cough, and sore throat.

Erythema multiforme major usually occurs as a drug reaction; has widespread symmetrical, bullous lesions that may become confluent; and includes erosions of the mucous membranes. Erythema is characteristically preceded by blisters on the lips, tongue, and buccal mucosa and a sore throat. Additional signs and symptoms early in the course of the disease include cough, vomiting, diarrhea, coryza, and epistaxis. Later signs and symptoms include fever, prostration, difficulty with oral intake due to mouth and lip lesions, conjunctivitis due to ulceration, vulvitis, and balanitis.

The maximal variant of this disease is considered by many to be Stevens-Johnson syndrome. This is a multisystem disorder and can occasionally be fatal. In addition to all signs and symptoms mentioned above, patients develop exfoliation of the skin from disruptions of bullae, although less than 10% of the body surface area is affected. These areas resemble second-degree thermal burns and should be cared for as such. Fever may rise to 102° to 104°F (38.9° to 40° C). The patient may also experience tachypnea; weak, rapid pulse; chest pain; malaise; and muscle or joint pain.

Erythema nodosum

Sudden bilateral eruption of tender erythematous nodules characterizes erythema nodosum. These firm, round, tender, protruding lesions usually appear in crops on the shins, knees, and ankles but may occur on the buttocks, arms, calves, and trunk as well. Other effects include mild fever, chills, malaise, muscle and joint pain and, possibly, swollen feet and ankles. Erythema nodosum is associated with various diseases, most notably inflammatory bowel disease, sarcoidosis, tuberculosis, and streptococcal and fungal infections.

Gout

Gout, which generally affects males ages 40 to 60, is characterized by tight and erythematous skin over an inflamed, edematous joint.

Lupus erythematosus

Both discoid and systemic lupus erythematosus (SLE) can produce a characteristic butterfly rash. This erythematous eruption may range from a blush with swelling to a scaly, sharply demarcated, macular rash with plaques that may spread to the forehead, chin, ears, chest, and other sun-exposed parts of the body.

With discoid lupus erythematosus, telangiectasia, hyperpigmentation, ear and nose deformity, and mouth, tongue, and eyelid lesions may occur.

With SLE, acute onset of erythema may also be accompanied by photosensitivity and mucous membrane ulcers, especially in the nose and mouth. Mottled erythema may occur on the hands, with edema around the nails and macular reddish purple lesions on the fingers. Telangiectasia occurs at the base of the nails or eyelids, along with purpura, petechiae, ecchymoses, and urticaria. Joint pain and stiffness are common. Other findings vary according to the body systems affected but typically include low-grade fever, malaise, weakness, headache, arthralgias, arthritis, depression, lymphadenopathy, fatigue, weight loss, anorexia, nausea, vomiting, diarrhea, and constipation.

Psoriasis

Silvery white scales over a thickened erythematous base usually affect the elbows, knees, chest, scalp, and intergluteal folds. The fingernails may become thick and pitted.

Raynaud’s disease

Typically, the skin on the hands and feet blanches and cools after exposure to cold and stress. Later, it becomes warm and purplish red.

Rosacea

Scattered erythema initially develops across the center of the face, followed by superficial telangiectases, papules, pustules, and nodules. Rhinophyma may occur on the lower half of the nose.

Rubella

Typically, flat solitary lesions join to form a blotchy pink erythematous rash that spreads rapidly to the trunk and extremities in rubella. Occasionally, small red lesions (Forschheimer spots) occur on the soft palate. Lesions clear in 4 to 5 days. The rash usually follows fever (up to 102° F [38.9°C]), headache, malaise, sore throat, a gritty eye sensation, lymphadenopathy, pain in the joints, and coryza.

Other causes

Drugs

Many drugs commonly cause erythema. (See Drugs associated with erythema.)

Herbal remedies

Ingestion of the fruit pulp of ginkgo biloba can cause severe erythema and edema of the mouth and rapid formation of vesicles. St. John’s wort can cause heightened sun sensitivity, resulting in erythema or “sunburn.”

Radiation and other treatments

Radiation therapy may produce dull erythema and edema within 24 hours. As the erythema fades, the skin becomes light brown and mildly scaly. Any treatment that causes an allergic reaction can also cause erythema.

Nursing considerations

Because erythema can cause fluid loss, closely monitor and replace fluids and electrolytes, especially in patients with burns or widespread erythema. Be sure to withhold all medications until the cause of the erythema has been identified. Then expect to administer an antibiotic and a topical or systemic corticosteroid.

For the patient with itching skin, expect to give soothing baths or apply open wet dressings containing starch, bran, or sodium bicarbonate; also administer an antihistamine and an analgesic as needed. Advise a patient with leg erythema to keep his legs elevated above heart level. For a burn patient with erythema, immerse the affected area in cold water, or apply a sheet soaked in cold water to reduce pain, edema, and erythema.

Prepare the patient for diagnostic tests, such as skin biopsy to detect cancerous lesions, cultures to identify infectious organisms, and sensitivity studies to confirm allergies.

Patient teaching

Teach the patient with a chronic disease, such as SLE or psoriasis, about the character of typical rashes so they can be alert to any flare-ups of the disease. Also, advise the patient to avoid sun exposure and to use sunblock when appropriate. Discuss measures to relieve itching.

Pictures

Erythema - 4933.png

Book Source Details

  • Book Title: Alarming Signs and Symptoms: Lippincott Manual of Nursing Practice Series
  • Author(s): Springhouse
  • Year of Publication: 2007
  • Copyright Details: Alarming Signs and Symptoms: Lippincott Manual of Nursing Practice Series, Copyright © 2007 Lippincott Williams & Wilkins.

More About Erythema nodosum

More Medical Textbooks Online about Erythema nodosum

Review other book chapters online related to Erythema nodosum:

Medical Books Excerpts
  • Erythema
  • "Handbook of Signs & Symptoms (Third Edition)" (2006)
  • Erythema Multiforme
  • "The 10-Minute Diagnosis Manual: Symptoms and Signs in the Time-Limited Encounter" (2000)
  • Erythema
  • "Alarming Signs and Symptoms: Lippincott Manual of Nursing Practice Series" (2007)
  • Erythema
  • "Signs & Symptoms: A 2-in-1 Reference for Nurses" (2007)
 

Copyright notice for book excerpts: Copyright © 2008 Lippincott Williams & Wilkins. All rights reserved.




More About This Book:
Title: Alarming Signs and Symptoms: Lippincott Manual of Nursing Practice Series
Authors: Springhouse
Publisher: Lippincott Williams & Wilkins
Copyright: 2007
ISBN: 1-58255-624-5

 » Next page: Erythema (Signs & Symptoms: A 2-in-1 Reference for Nurses)

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