Prevalence and Incidence of Exfoliative dermatitis
Exfoliative dermatitis Prevalence: Book Excerpts
Prevalence/Incidence of Exfoliative dermatitis: Online Medical Books
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Review excerpts from medical books online, free, without registration,
for more information about the prevalence and/or incidence of Exfoliative dermatitis.
Dermatitis:
Causes and incidence
(Professional Guide to Diseases (Eighth Edition))
The cause of atopic dermatitis is unknown, but a genetic predisposition may be exacerbated by such factors as food allergies, infections, irritating chemicals, temperature and humidity, and emotions. Approximately 10% of childhood cases are due to allergy to certain foods, particularly eggs, peanuts, milk, fish, soy, and wheat. Atopic dermatitis tends to flare up in response to extremes in temperature and humidity. Other causes of flare-ups are sweating and psychological stress.
An important secondary cause of atopic dermatitis is irritation, which seems to change the epidermal structure, allowing immunoglobulin (Ig) E activity to increase. Consequently, chronic skin irritation usually continues even after exposure to the allergen has ended or after the irritation has been systemically controlled.
Atopic dermatitis is most common in infants, usually developing between ages 1 month and 1 year, commonly in those with strong family histories of atopic disease. At least half of those cases clear by age 36 months. These children often acquire other atopic disorders as they grow older. Typically, this form of dermatitis flares and subsides repeatedly before finally resolving during adolescence. However, it can persist into adulthood. In adults, it’s generally chronic or recurring.
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Source: Professional Guide to Diseases (Eighth Edition), 2005
Wilson's disease:
Causes and incidence
(Professional Guide to Diseases (Eighth Edition))
Wilson’s disease is inherited as an autosomal recessive trait only when both parents carry the abnormal gene. There is a 25% chance that carrier parents will transmit Wilson’s disease (and a 50% chance that they will transmit the carrier state) to each of their offspring. The disease usually occurs among eastern Europeans, Sicilians, and other southern Italians.
Wilson’s disease causes excessive intestinal absorption of copper and subsequent decreased excretion of copper in the stool. Copper accumulates first in the liver. As liver cells die, they release copper into the bloodstream, which carries it to other tissues. For example, in the kidneys, excretion of excessive amounts of unbound copper in urine (hypercupriuria) results from ceruloplasmin deficiency, a serum enzyme normally bound to copper. The deposit of copper in the tissue decreases serum copper (hypocupremia).
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Source: Professional Guide to Diseases (Eighth Edition), 2005
Wilson Disease:
Wilson Disease - epidemiology
(The 5-Minute Pediatric Consult)
Children usually present with hepatic manifestations; adolescents and young adults may present with neurologic symptoms.
Wilson Disease - incidence
- Incidence is 15–25 per million.
- Worldwide carrier rate is 1:100.
Wilson Disease - prevalence
- Prevalence is 1:30,000.
- Most cases present between ages 5 and 35.
- Worldwide distribution
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Source: The 5-Minute Pediatric Consult, 2008
About prevalence and incidence statistics:
The term 'prevalence' of Exfoliative dermatitis usually refers to the estimated population
of people who are managing Exfoliative dermatitis at any given time.
The term 'incidence' of Exfoliative dermatitis refers to the annual diagnosis rate,
or the number of new cases of Exfoliative dermatitis diagnosed each year.
Hence, these two statistics types can differ:
a short-lived disease like flu can have high annual incidence but low prevalence,
but a life-long disease like diabetes has a low annual incidence but high prevalence.
For more information see about prevalence and incidence statistics.
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