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Radical nephrectomy, with or without regional lymph node dissection, offers the only chance of cure. Because the disease is radiation resistant, radiation is used only if the cancer spreads to the perinephric region or the lymph nodes or if the primary tumor or metastatic sites can't be fully excised. In these cases, high radiation doses are used.
Chemotherapy has been only erratically effective against kidney cancer. Fluorouracil, cyclophosphamide, vinblastine, vincristine, cisplatin, tamoxifen, teniposide, interferons, and hormones such as medroxyprogesterone and testosterone have been used, usually with poor results. Biotherapy (interferon and interleukins), commonly used in advanced disease, has produced few durable remissions.
Source: Professional Guide to Diseases (Eighth Edition), 2005
Radical nephrectomy, with or without regional lymph node dissection, offers the only chance of cure. Because the disease is radiation-resistant, radiation is used only if the cancer spreads to the perinephric region or the lymph nodes or if the primary tumor or metastatic sites can’t be fully excised. In such cases, high doses of radiation are used.
Chemotherapy has been only erratically effective against kidney cancer and includes various drugs. Interferons and hormones, such as medroxyprogesterone and testosterone, have also been used. Biotherapy (lymphokine-activated killer cells with recombinant interleukin-2) shows promise, but causes adverse reactions. Interferon is somewhat effective in advanced disease. Hormone therapy may be tried in advanced cases.
Source: Handbook of Diseases, 2003
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